Last update :
03/02/2023
General anesthetic   Pentobarbital sodium  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Nembutal United States of America
Compatibility   Injection   Compatibility : Pentobarbital sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Pentobarbital sodium 2 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Chlorpromazine hydrochloride
3596
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Droperidol
4009
Immediate precipitation Incompatible
Injection Pentobarbital sodium 5 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Immediate instability of the emulsion Incompatible
Injection Pentobarbital sodium 5 mg/ml
Parenteral nutrition (with lipids) 1415
Loss of turbidity Incompatible
Injection Pentobarbital sodium 5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Atracurium besylate
3676
Precipitation after 24 hours Incompatible
Injection Pentobarbital sodium 28.6 mg/ml
Injection Atropine sulfate 0.17 mg/ml
None 1203
Immediate precipitation Incompatible
Injection Pentobarbital sodium 25 mg/ml
Injection Cimetidine hydrochloride 75 mg/ml
None 1203
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Cimetidine hydrochloride
3592
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Clindamycin phosphate
3526
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Erythromycin lactobionate
3674
Immediate precipitation Incompatible
Injection Pentobarbital sodium
Injection Esketamine
4700
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Fentanyl citrate
3503
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Glycopyrronium bromide
3599
Compatible
Injection Pentobarbital sodium 5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Morphine sulfate
3531
Immediate precipitation Incompatible
Injection Pentobarbital sodium 48 mg/ml
Parenteral nutrition (binary mixture) 3379
Immediate precipitation Incompatible
Injection Pentobarbital sodium
Injection Hydroxocobalamin
3932
Immediate precipitation Incompatible
Injection Pentobarbital sodium
Injection Ketamine hydrochloride
3501
Immediate precipitation Incompatible
Injection Pentobarbital sodium 5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Immediate precipitation Incompatible
Injection Pentobarbital sodium 33.33 mg/ml
Injection Midazolam hydrochloride 1.67 mg/ml
None 404
Immediate precipitation Incompatible
Injection Pentobarbital sodium 25 & 50 mg/ml
Injection Nalbuphine hydrochloride 2,5 >> 10 mg/ml
616
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Norepinephrine bitartrate
642
Immediate turbidity Incompatible
Injection Pentobarbital sodium
Injection Pethidine hydrochloride
3525
Instability of the emulsion after 4 hours Incompatible
Injection Pentobarbital sodium 50 mg/ml
Injection Propofol
660
Compatible
Injection Pentobarbital sodium 5 mg/ml
Injection Propofol 10 mg/ml
None 300
Unspecified incompatibility Incompatible
Injection Pentobarbital sodium
Injection Suxamethonium chloride
3631
Immediate precipitation Incompatible
Injection Pentobarbital sodium
Injection Trimebutine
3931
Compatible
Injection Pentobarbital sodium 5 mg/ml
Injection Valproic acid 2 & 20 mg/ml
NaCl 0,9% or Glucose 5% 4428
Compatible
Injection Pentobarbital sodium 0.2 mg/ml
Injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
Injection Pentobarbital sodium 5 mg/ml
Parenteral nutrition (binary mixture) 301

  Mentions Légales