Monographie - Ketamine hydrochloride

Last update :
19/11/2024

Ketamine hydrochloride

Chemical structure

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Aescoket	Italy
Anesket	Colombia, Mexico
Calypsol	Hungary, Malaysia, Poland, Romania, Thailand
Inducmina	Argentina, Peru
Kanox	Malaysia
Keiram	Egypt, Venezuela
Keta	Germany, India
Keta Hameln	Peru
Ketafast	India
Ketajet	India
Ketalar	Australia, Belgium, Brazil, Canada, Chile, Colombia, Denmark, Finland, Great Britain, Ireland, Luxembourg, Netherlands, New Zealand, Norway, Portugal, Sweden, Turkey, United Arab Emirates, United States of America
Ketalin	Mexico
Ketamar	Egypt
Ketamax	India, Venezuela
Ketamin	Germany
Ketamina	Argentina, Chile, Colombia, Peru, Venezuela
Ketamine	Canada, Egypt, France, Ireland, Italy, Malaysia, New Zealand, Romania, Tunisia, United States of America
Ketanest	Poland
Ketanir	Colombia, Ecuador, Peru
Ketashort	Colombia
Ketava	Malaysia
Ketmin	India
Ketolar	Spain
Ketsia	India
Kmin	India
Tekam	Saudi Arabia, United Arab Emirates

References : Ketamine hydrochloride

	Type	Publication
181	Journal	Fuchao Chen, Hui Xiong, Jinguo Yang, Baoxia Fang, Jun Zhu, Benhong Zhou. Butorphanol and Ketamine Combined in Infusion Solutions for Patient-Controlled Analgesia Administration: A Long-Term Stability Study. Med Sci Monit 2015 ; 21:1138-1145.
300	Journal	Trissel LA, Gilbert DL, Martinez JF. Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration. Am J Health-Syst Pharm 1997 ; 54: 1287-1292.
321	Journal	Ambados F. Compatibility of ketamine hydrochloride and meperidine hydrochloride. Am J Health-Syst Pharm 1997 ; 54: 205.
365	Journal	Junfeng Gu, Wengang Qin, Fuchao Chen, Zhongyuan Xia. Long-Term Stability of Tramadol and Ketamine Solutions for Patient-Controlled Analgesia Delivery. Med Sci Monit 2015 ; 21:2528-2534.
660	Journal	Michaels MR, Stauffer GL, Haas DP. Propofol compatibility with other intravenous drug products - Two new methods of evaluating IV emulsion compatibility. Ann Pharmacotherapy 1996 ; 30: 228-232.
980	Journal	Ambados F. Compatibility of morphine and ketamine for subcutaneous infusion. Aust J Hosp Pharm 1995 ; 25: 352.
1714	Journal	Gupta VD. Stability of ketamine hydrochloride injection after reconstitution in water for injection and storage in 1-ml tuberculin polypropylene syringes for pediatric use. Int J Pharm Compound 2002 ; 6: 316-317.
1759	Journal	Servais H, Tulkens PM. Stability and compatibility of ceftazidime administered by continuous infusion to intensive care patients. Antimicrob Agents Chemother 2001 ; 45: 2643-2647.
1864	Journal	Lau MH, Hackman C, Morgan DJ. Compatibility of ketamine and morphin injections. Pain 1998 ; 75: 389-390.
1934	Journal	Ambados F, Brealey J. Compatibility of ketamine hydrochloride and fentanyl citrate in polypropylene syringes. Am J Health-Syst Pharm 2004 ; 61: 1438-1445.
1993	Journal	Lee DKT, Wang DP, Harsono R, Wong CY. Compatibility of fentanyl citrate, ketamine hydrochloride, and droperidol in 0.9% sodium chloride injection stored in polyvinyl chloride bags. Am J Health-Syst Pharm 2005 ; 62: 1190-1192.
2022	Journal	Watson DG, Lin M, Morton A, Cable CG, McArthur DA. Compatibility and stability of dexamethasone sodium phosphate and ketamine hydrochloride subcutaneous infusions in polypropylene syringes. J Pain Symptom Manage 2005 ; 30: 80-86.
2109	Journal	Pelletier E, Forest JM, Hildgen P. Compatibilité de la kétamine injectable lors de l’administration en dérivé avec d’autres médicaments usuels. Pharmactuel 2006 ; 39: 71-75.
2141	Journal	Barinian N, Chanteux H, Viaene E, Servais H, Tulkens PM. Stability and compatibility study of cefepime in comparaison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory treatment of cystic fibrosis patients and to administration in intensive care units. J Antimicrob Chemother 2003 ; 51: 651-658.
2231	Journal	de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S. Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection. J Antimicrob Chemother 2008 ; 61, 2: 382-388.
2287	Journal	Stucki MC, Leury-Souverain S, Sautter AM, Sadeghipour F, Bonnabry P. Development of ready-to-use ketamine hydrochloride syringes for safe use in post-operative pain. EJHP Science 2008 ; 14, 1: 14-18.
2322	Journal	Donnelly R.F. Physical Compatibility and Chemical Stability of Ketamine–Morphine Mixtures in Polypropylene Syringes. Can J Hosp Pharm 2009 ; 62, 1
2329	Journal	Donnely R.F, Willman E, Andolfatto G. Stability of Ketamine-Propofol mixtures for procedural sedation and analgesia in the emergency department. Can J Hosp Pharm 2008 ; 61, 6: 426-430.
2336	Journal	Ensom M.H.H, Decarie D, Leung K, MontgomeryC Stability of Hydromorphone–Ketamine Solutions in Glass Bottles, Plastic Syringes, and IV Bags for Pediatric Use Can J Hosp Pharm 2009 ; 62, 2: 112-118.
2350	Journal	Roy J.J, Hildgen P. Stability of morphine-ketamine in 0.9% sodium chloride injection packaged in syringes, plastic bags and MEDICATION CASSETTE Reservoirs. Int J Pharm Compound 2000 ; 4, 3: 225-228.
2900	Journal	Hines S, Pleasance S. Compatibility of an injectable high strength oxycodone formulation with typical diluents, syringes, tubings,infusion bags and drugs for potential co-administration. EJHP 2009 ; 15, 5: 32-38.
3012	Journal	Sullivan T, Forrest J.M, Leclair G. Compatibility of Cloxacillin Sodium with Selected Intravenous Drugs During Simulated Y-Site Administration Hosp Pharm 2015 ; 50, 3: 214-220.
3372	Journal	Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S. Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine. Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3385	Journal	Raverdi V, Ampe E, Hecq JD, Tulkens PM. Stability and compatibility of vancomycin for administration by continuous infusion. J Antimicrob Chemother 2013 ; 68: 1179-1182.
3408	Journal	Tollec S, Touzin K, Pelletier E, Forest J.M. Evaluation visuelle de la compatibilité physique de la naloxone avec d’autres médicaments intraveineux usuels. Pharmactuel 2013 ; 46, 1 : 16-21.
3435	Journal	Donnelly R.F. Stability of Diluted Ketamine Packaged in Glass Vials. Can J Hosp Pharm 2013 ; 66, 3 : 198.
3501	Manufacturer	Ketamine hydrochloride (Ketalar®) - Summary of Product Characteristics Pfizer 2011
3705	Journal	Knudsen L, Eisend S, Haake N, Kunze T. Physicochemical compatibility of commonly used analgesics and sedatives in the intensive care medicine. EJHP 2014 ;21:161-166
3824	Journal	Boudi S, Roy H, Forest JM, Leclair G. Compatibilité physique de l'association amoxicilline-acide clavulanique en injection avec plusieurs autres médicaments lors d'une administration en Y. Pharmactuel 2023 2023;56,3:91-98
3859	Journal	Foy G, Poinsignon V, Mercier L, Laurent S, Paci A. Microbiological and Physico-Chemical Stability of Ketamine Solution for Patient-Controlled Analgesia Systems. RRJHCP 2016 ; 1, 3: 31-37.
3874	Journal	Huvelle S, Godet M, Hecq J.D, Gillet P, Bihin B, Jamart J, Galanti L. Long-term stability of ketamine hydrochloride 50 mg/ml injection in 3 ml syringes Ann Pharm Fr 2016 ; 74: 283-287.
3911	Journal	Closset M, Hecq J D, Gonzalez E, Bihin B, Jamart J, L Galanti L. Does an interaction exist between ketamine hydrochloride and Becton Dickinson syringes? EJHP 2017 ; 24: 230-234.
3932	Manufacturer	Hydroxocobalamine (Cyanokit®) - Résumé des caractéristiques du produit Serb Laboratoire 2015
3964	Journal	Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G. Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments. Pharmactuel 2017 ; 50,1 : 27-33.
4011	Journal	Gersonde F, Eisend S, Haake N, Kunze T. Physicochemical compatibility and emulsion stability of propofol with commonly used analgesics and sedatives in an intensive care unit. EJHP 2016 2016;0:1-11
4115	Journal	Fang B, Wang L, Gu J, Chen F, Shi X. Physicochemical stability of ternary admixtures of butorphanol, ketamine, and droperidol in polyolefin bags for patient-controlled analgesia use. Drug Design Dev Ther 2016 ;10:3873-3878
4143	Journal	Daouphars M, Hervou?t C.H, Bohn P, Martin D, Rouvet J, Basuyau F, Varin R. Physicochemical stability of oxycodone-ketamine solutions in polypropylene syringe and polyvinyl chloride bag for patient-controlled analgesia use. EJHP 2016 ; 25, 4
4157	Journal	Izgi M, Basara B, Muderrisoglu A, Yilbas A.A, Uluer M.S, Celebioglu B. Evaluation of the stability and stratification of propofol and ketamine mixtures for pediatric anesthesia. Pediatric Anesthesia 2018
4303	Journal	Anderson C, MacKay M. Stability of Fentanyl Citrate, Hydromorphone Hydrochloride, Ketamine Hydrochloride, Midazolam, Morphine Sulfate, and Pentobarbital Sodium in Polypropylene Syringes. Pharmacy 2015 3, 379-385.
4319	Journal	Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G. Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs. Hosp Pharm 2020 ; 55, 5: 332-337.
4350	Journal	Beiler B, Barraud D, Vigneron J, Demor? B. Physicochemical stability of an admixture of lidocaine and ketamine in polypropylene syringe used in opioid-free anaesthesia. EJHP 2019 ;0:1-5
4389	Journal	Côté K, Correal F, Metras M.E, Friciu M, Forest J.M, Leclair G. Compatibilité physique des médicaments administrés en Y aux soins intensifs, en particulier la dexmédétomidine, le lévosimendan et la kétamine. Pharmactuel 2019 ;52,4:206-213
4435	Journal	Hanifah S, Nugroho B.H, Chabib L. Compatibility of acetaminophen with central nervous system medications during simulated Y-site injection. Anaesthesiol Intensive Ther 2020 ; 52, 1: 23-27.
4436	Journal	Hanifah S, Kennedy R.A; Ball P.A. Extended compatibility of fentanyl and ketamine in dextrose 5%. Anaesthesiol Intensive Ther 2018 ; 50, 3: 221-225.
4491	Journal	De Basagoiti A, Katsumiti A, Abascal S, Bustinza A, López-Giménez L.R, Pilar P, De Miguel M, Campino A. Physical compatibility of alprostadil with selected drugs commonly used in the neonatal intensive care units. Eur J Pedia 2020
4507	Journal	Ross E, Salinas A, Petty K, Her C, Carpenter J. Compatibility of medications with intravenous lipid emulsions: Effects of simulated Y-site mixing. Am J Health-Syst Pharm 2020 ;77,23:1980-1985
4603	Journal	Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G. Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration. Hosp Pharm 2021 ; 56, 4: 228-234.
4651	Journal	De Basagoiti A, Katsumiti A, Abascal S, Bustinza A, López-Giménez L.R, Pascual P, De Miguel M, Campino A. Physical compatibility of alprostadil with selected drugs commonly used in the neonatal intensive care units. Eur J Pedia 2021 ;180,1169–1176.
4742	Journal	Macoviciuc M, Nguyen C, Forest J-M, Leclair G. Compatibilité physique de l’acétaminophène injectable avec 102 autres médicaments lors d’une administration en Y. Pharmactuel 2022 ; 55, 4: 247-255.
4842	Journal	Souha H Y, Alka G, Yunmei S, Nicole E W, Sanjay G. Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors Drug Design Dev Ther 2024 Drug Design, Development

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