Dernière mise à jour :
19/11/2024
Anesthésique général   Ketamine hydrochloride  
injectable
Solution buvable
Stabilité des solutions Stabilité en mélange Facteur influençant la stabilité Compatibilités Voie d’administration Bibliographie pdf
   Structure chimique  

Noms commerciaux   Noms commerciaux     

Les noms commerciaux sont donnés à titre indicatif et la composition en excipients peut être différente selon les pays et selon les laboratoires

Aescoket Italie
Anesket Colombie, Mexique
Calypsol Hongrie, Malaisie, Pologne, Roumanie, Thaïlande
Inducmina Argentine, Pérou
Kanox Malaisie
Keiram Egypte, Vénézuela
Keta Allemagne, Inde
Keta Hameln Pérou
Ketafast Inde
Ketajet Inde
Ketalar Australie, Belgique, Brésil, Canada, Chili, Colombie, Danemark, Emirats Arabes Unis , Etats Unis d’Amérique, Finlande, Grande Bretagne, Irlande, Luxembourg, Norvège, Nouvelle Zélande, Pays bas, Portugal, Suède, Turquie
Ketalin Mexique
Ketamar Egypte
Ketamax Inde, Vénézuela
Ketamin Allemagne
Ketamina Argentine, Chili, Colombie, Pérou, Vénézuela
Ketamine Canada, Egypte, Etats Unis d’Amérique, France, Irlande, Italie, Malaisie, Nouvelle Zélande, Roumanie, Tunisie
Ketanest Pologne
Ketanir Colombie, Equateur, Pérou
Ketashort Colombie
Ketava Malaisie
Ketmin Inde
Ketolar Espagne
Ketsia Inde
Kmin Inde
Tekam Arabie Saoudite, Emirats Arabes Unis
Bibliographie   injectable   Bibliographie : Ketamine hydrochloride  
Type Source
181 Revue Fuchao Chen, Hui Xiong, Jinguo Yang, Baoxia Fang, Jun Zhu, Benhong Zhou.
Butorphanol and Ketamine Combined in Infusion Solutions for Patient-Controlled Analgesia Administration: A Long-Term Stability Study.
Med Sci Monit 2015 ; 21:1138-1145.
300 Revue Trissel LA, Gilbert DL, Martinez JF.
Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 1287-1292.
321 Revue Ambados F.
Compatibility of ketamine hydrochloride and meperidine hydrochloride.
Am J Health-Syst Pharm 1997 ; 54: 205.
365 Revue Junfeng Gu, Wengang Qin, Fuchao Chen, Zhongyuan Xia.
Long-Term Stability of Tramadol and Ketamine Solutions for Patient-Controlled Analgesia Delivery.
Med Sci Monit 2015 ; 21:2528-2534.
660 Revue Michaels MR, Stauffer GL, Haas DP.
Propofol compatibility with other intravenous drug products - Two new methods of evaluating IV emulsion compatibility.
Ann Pharmacotherapy 1996 ; 30: 228-232.
980 Revue Ambados F.
Compatibility of morphine and ketamine for subcutaneous infusion.
Aust J Hosp Pharm 1995 ; 25: 352.
1714 Revue Gupta VD.
Stability of ketamine hydrochloride injection after reconstitution in water for injection and storage in 1-ml tuberculin polypropylene syringes for pediatric use.
Int J Pharm Compound 2002 ; 6: 316-317.
1759 Revue Servais H, Tulkens PM.
Stability and compatibility of ceftazidime administered by continuous infusion to intensive care patients.
Antimicrob Agents Chemother 2001 ; 45: 2643-2647.
1864 Revue Lau MH, Hackman C, Morgan DJ.
Compatibility of ketamine and morphin injections.
Pain 1998 ; 75: 389-390.
1934 Revue Ambados F, Brealey J.
Compatibility of ketamine hydrochloride and fentanyl citrate in polypropylene syringes.
Am J Health-Syst Pharm 2004 ; 61: 1438-1445.
1993 Revue Lee DKT, Wang DP, Harsono R, Wong CY.
Compatibility of fentanyl citrate, ketamine hydrochloride, and droperidol in 0.9% sodium chloride injection stored in polyvinyl chloride bags.
Am J Health-Syst Pharm 2005 ; 62: 1190-1192.
2022 Revue Watson DG, Lin M, Morton A, Cable CG, McArthur DA.
Compatibility and stability of dexamethasone sodium phosphate and ketamine hydrochloride subcutaneous infusions in polypropylene syringes.
J Pain Symptom Manage 2005 ; 30: 80-86.
2109 Revue Pelletier E, Forest JM, Hildgen P.
Compatibilité de la kétamine injectable lors de l’administration en dérivé avec d’autres médicaments usuels.
Pharmactuel 2006 ; 39: 71-75.
2141 Revue Barinian N, Chanteux H, Viaene E, Servais H, Tulkens PM.
Stability and compatibility study of cefepime in comparaison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory treatment of cystic fibrosis patients and to administration in intensive care units.
J Antimicrob Chemother 2003 ; 51: 651-658.
2231 Revue de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S.
Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.
J Antimicrob Chemother 2008 ; 61, 2: 382-388.
2287 Revue Stucki MC, Leury-Souverain S, Sautter AM, Sadeghipour F, Bonnabry P.
Development of ready-to-use ketamine hydrochloride syringes for safe use in post-operative pain.
EJHP Science 2008 ; 14, 1: 14-18.
2322 Revue Donnelly R.F.
Physical Compatibility and Chemical Stability of Ketamine–Morphine Mixtures in Polypropylene Syringes.
Can J Hosp Pharm 2009 ; 62, 1
2329 Revue Donnely R.F, Willman E, Andolfatto G.
Stability of Ketamine-Propofol mixtures for procedural sedation and analgesia in the emergency department.
Can J Hosp Pharm 2008 ; 61, 6: 426-430.
2336 Revue Ensom M.H.H, Decarie D, Leung K, MontgomeryC
Stability of Hydromorphone–Ketamine Solutions in Glass Bottles, Plastic Syringes, and IV Bags for Pediatric Use
Can J Hosp Pharm 2009 ; 62, 2: 112-118.
2350 Revue Roy J.J, Hildgen P.
Stability of morphine-ketamine in 0.9% sodium chloride injection packaged in syringes, plastic bags and MEDICATION CASSETTE Reservoirs.
Int J Pharm Compound 2000 ; 4, 3: 225-228.
2900 Revue Hines S, Pleasance S.
Compatibility of an injectable high strength oxycodone formulation with typical diluents, syringes, tubings,infusion bags and drugs for potential co-administration.
EJHP 2009 ; 15, 5: 32-38.
3012 Revue Sullivan T, Forrest J.M, Leclair G.
Compatibility of Cloxacillin Sodium with Selected Intravenous Drugs During Simulated Y-Site Administration
Hosp Pharm 2015 ; 50, 3: 214-220.
3372 Revue Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S.
Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine.
Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3385 Revue Raverdi V, Ampe E, Hecq JD, Tulkens PM.
Stability and compatibility of vancomycin for administration by continuous infusion.
J Antimicrob Chemother 2013 ; 68: 1179-1182.
3408 Revue Tollec S, Touzin K, Pelletier E, Forest J.M.
Evaluation visuelle de la compatibilité physique de la naloxone avec d’autres médicaments intraveineux usuels.
Pharmactuel 2013 ; 46, 1 : 16-21.
3435 Revue Donnelly R.F.
Stability of Diluted Ketamine Packaged in Glass Vials.
Can J Hosp Pharm 2013 ; 66, 3 : 198.
3501 Laboratoire Ketamine hydrochloride (Ketalar®) - Summary of Product Characteristics
Pfizer 2011
3705 Revue Knudsen L, Eisend S, Haake N, Kunze T.
Physicochemical compatibility of commonly used analgesics and sedatives in the intensive care medicine.
EJHP 2014 ;21:161-166
3824 Revue Boudi S, Roy H, Forest JM, Leclair G.
Compatibilité physique de l'association amoxicilline-acide clavulanique en injection avec plusieurs autres médicaments lors d'une administration en Y.
Pharmactuel 2023 2023;56,3:91-98
3859 Revue Foy G, Poinsignon V, Mercier L, Laurent S, Paci A.
Microbiological and Physico-Chemical Stability of Ketamine Solution for Patient-Controlled Analgesia Systems.
RRJHCP 2016 ; 1, 3: 31-37.
3874 Revue Huvelle S, Godet M, Hecq J.D, Gillet P, Bihin B, Jamart J, Galanti L.
Long-term stability of ketamine hydrochloride 50 mg/ml injection in 3 ml syringes
Ann Pharm Fr 2016 ; 74: 283-287.
3911 Revue Closset M, Hecq J D, Gonzalez E, Bihin B, Jamart J, L Galanti L.
Does an interaction exist between ketamine hydrochloride and Becton Dickinson syringes?
EJHP 2017 ; 24: 230-234.
3932 Laboratoire Hydroxocobalamine (Cyanokit®) - Résumé des caractéristiques du produit
Serb Laboratoire 2015
3964 Revue Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G.
Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments.
Pharmactuel 2017 ; 50,1 : 27-33.
4011 Revue Gersonde F, Eisend S, Haake N, Kunze T.
Physicochemical compatibility and emulsion stability of propofol with commonly used analgesics and sedatives in an intensive care unit.
EJHP 2016 2016;0:1-11
4115 Revue Fang B, Wang L, Gu J, Chen F, Shi X.
Physicochemical stability of ternary admixtures of butorphanol, ketamine, and droperidol in polyolefin bags for patient-controlled analgesia use.
Drug Design Dev Ther 2016 ;10:3873-3878
4143 Revue Daouphars M, Hervou?t C.H, Bohn P, Martin D, Rouvet J, Basuyau F, Varin R.
Physicochemical stability of oxycodone-ketamine solutions in polypropylene syringe and polyvinyl chloride bag for patient-controlled analgesia use.
EJHP 2016 ; 25, 4
4157 Revue Izgi M, Basara B, Muderrisoglu A, Yilbas A.A, Uluer M.S, Celebioglu B.
Evaluation of the stability and stratification of propofol and ketamine mixtures for pediatric anesthesia.
Pediatric Anesthesia 2018
4303 Revue Anderson C, MacKay M.
Stability of Fentanyl Citrate, Hydromorphone Hydrochloride, Ketamine Hydrochloride, Midazolam, Morphine Sulfate, and Pentobarbital Sodium in Polypropylene Syringes.
Pharmacy 2015 3, 379-385.
4319 Revue Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G.
Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs.
Hosp Pharm 2020 ; 55, 5: 332-337.
4350 Revue Beiler B, Barraud D, Vigneron J, Demor? B.
Physicochemical stability of an admixture of lidocaine and ketamine in polypropylene syringe used in opioid-free anaesthesia.
EJHP 2019 ;0:1-5
4389 Revue Côté K, Correal F, Metras M.E, Friciu M, Forest J.M, Leclair G.
Compatibilité physique des médicaments administrés en Y aux soins intensifs, en particulier la dexmédétomidine, le lévosimendan et la kétamine.
Pharmactuel 2019 ;52,4:206-213
4435 Revue Hanifah S, Nugroho B.H, Chabib L.
Compatibility of acetaminophen with central nervous system medications during simulated Y-site injection.
Anaesthesiol Intensive Ther 2020 ; 52, 1: 23-27.
4436 Revue Hanifah S, Kennedy R.A; Ball P.A.
Extended compatibility of fentanyl and ketamine in dextrose 5%.
Anaesthesiol Intensive Ther 2018 ; 50, 3: 221-225.
4491 Revue De Basagoiti A, Katsumiti A, Abascal S, Bustinza A, López-Giménez L.R, Pilar P, De Miguel M, Campino A.
Physical compatibility of alprostadil with selected drugs commonly used in the neonatal intensive care units.
Eur J Pedia 2020
4507 Revue Ross E, Salinas A, Petty K, Her C, Carpenter J.
Compatibility of medications with intravenous lipid emulsions: Effects of simulated Y-site mixing.
Am J Health-Syst Pharm 2020 ;77,23:1980-1985
4603 Revue Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G.
Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration.
Hosp Pharm 2021 ; 56, 4: 228-234.
4651 Revue De Basagoiti A, Katsumiti A, Abascal S, Bustinza A, López-Giménez L.R, Pascual P, De Miguel M, Campino A.
Physical compatibility of alprostadil with selected drugs commonly used in the neonatal intensive care units.
Eur J Pedia 2021 ;180,1169–1176.
4742 Revue Macoviciuc M, Nguyen C, Forest J-M, Leclair G.
Compatibilité physique de l’acétaminophène injectable avec 102 autres médicaments lors d’une administration en Y.
Pharmactuel 2022 ; 55, 4: 247-255.
4842 Revue Souha H Y, Alka G, Yunmei S, Nicole E W, Sanjay G.
Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors
Drug Design Dev Ther 2024 Drug Design, Development

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