Last update :
16/06/2024
References   References 4729  
Type : Journal
Web link : https://doi.org/10.3390/ pharmaceutics15010208

Research teams : Bangkok - Mahidol University, Faculty of Pharmacy, Bangkok
Authors : Leanpolchareanchai J, Tangteerakoon P, Supapsophon P, Sukavatcharin S, Simaroj P, Suksiriworapong J.
Title : Extemporaneous Preparation of 20 mg/mL Ganciclovir in Artificial Tears in Comparison with SterileWater for Ophthalmic Administration: Formulation and Stability Study.
Reference : Pharmaceutics ; 15, 208. 2023

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Measurement of osmolality PH measurement 
Comments : 

List of drugs
Eye-dropsGanciclovir Antiviral
Stability in solutions Plastic bottle Commercial Drug product 100 mg
® = La Roche
Water for injection >> 5 mL
2-8°C Protect from light
84 Day
Stability in solutions Plastic bottle Commercial Drug product 100 mg
® = La Roche
Water for injection >> 5 mL
28-32°C Protect from light
56 Day

  Mentions Légales