Last update :
18/07/2024
References   References 4389  
Type : Journal

Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Côté K, Correal F, Metras M.E, Friciu M, Forest J.M, Leclair G.
Title : Compatibilité physique des médicaments administrés en Y aux soins intensifs, en particulier la dexmédétomidine, le lévosimendan et la kétamine.
Reference : Pharmactuel ;52,4:206-213 2019

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAcetazolamide Diuretic
Compatible 100 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionAlprostadil Vasodilator
Compatible 500 µg/ml + injectionDexmedetomidine 100 µg/ml
Compatible 500 µg/ml + injectionKetamine hydrochloride 50 mg/ml
Compatible 500 µg/ml + injectionMilrinone lactate 1 mg/ml
injectionAmikacin sulfate Antibiotic
Compatible 250 mg/ml + injectionMeropenem 50 mg/ml
injectionAminophylline Various
Incompatible 25 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionAmpicillin sodium Antibiotic
Compatible 100 mg/ml + injectionPotassium chloride 2 mEq/l
injectionAztreonam Antibiotic
Compatible 100 mg/ml + injectionMeropenem 50 mg/ml
injectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionCaffeine citrate Respiratory stimulant
Compatible 10 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionCefoxitin sodium Antibiotic
Incompatible 100 mg/ml + injectionImipenem - cilastatin sodium 50 mg/ml
injectionCeftazidime Antibiotic
Compatible 100 mg/ml + injectionMeropenem 50 mg/ml
injectionCiclosporin Immunosuppressant
Compatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCloxacillin sodium Antibiotic
Compatible 100 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 4 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDexmedetomidine Sympathomimetic
Compatible 100 µg/ml + injectionAcetazolamide 100 mg/ml
Compatible 100 µg/ml + injectionAlprostadil 500 µg/ml
Compatible 100 µg/ml + injectionBenztropine mesylate 1 mg/ml
Compatible 100 µg/ml + injectionCaffeine citrate 10 mg/ml
Compatible 100 µg/ml + injectionCloxacillin sodium 100 mg/ml
Compatible 100 µg/ml + injectionDimenhydrinate 10 mg/ml
Compatible 100 µg/ml + injectionHuman albumin 250 mg/ml
Compatible 100 µg/ml + injectionHydralazine hydrochloride 20 mg/ml
Compatible 100 µg/ml + injectionKetamine hydrochloride 50 mg/ml
Compatible 100 µg/ml + injectionLevosimendan 2.5 mg/ml
Incompatible 100 µg/ml + injectionMicafungin 20 mg/ml
Compatible 100 µg/ml + injectionMilrinone lactate 1 mg/ml
Compatible 100 µg/ml + injectionN-acetylcysteine 200 mg/ml
Compatible 100 µg/ml + injectionPenicillin G sodium 0,5 MUI/ml
Compatible 100 µg/ml + injectionPhentolamine mesylate 5 mg/ml
Compatible 100 µg/ml + injectionSalbutamol sulfate 1 mg/ml
Compatible 100 µg/ml + injectionThiamine hydrochloride 100 mg/ml
Compatible 100 µg/ml + injectionTranexamic acid 100 mg/ml
Compatible 100 µg/ml + injectionValproic acid 100 mg/ml
injectionDimenhydrinate Antihistamine (H1)
Compatible 10 mg/ml + injectionDexmedetomidine 100 µg/ml
Compatible 10 mg/ml + injectionPotassium chloride 2 mEq/l
injectionDopamine hydrochloride Cardiotonic
Compatible 3,2 mg/ml + injectionFurosemide 10 mg/ml
Compatible 3,2 mg/ml + injectionHeparin sodium 100 UI/ml
Incompatible 3,2 mg/ml + injectionInsulin 100 UI/ml
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + injectionLevosimendan 2,5 mg/ml
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionKetamine hydrochloride 50 mg/ml
Compatible 10 mg/ml + injectionMilrinone lactate 1 mg/ml
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionHeparin sodium 100 UI/ml
Compatible 50 µg/ml + injectionLevosimendan 2,5 mg/ml
injectionFurosemide Diuretic
Compatible 10 mg/ml + injectionDopamine hydrochloride 3,2 mg/ml
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionDopamine hydrochloride 3,2 mg/ml
Compatible 100 UI/ml + injectionFentanyl citrate 50 µg/ml
Compatible 100 UI/ml + injectionLevosimendan 2,5 mg/ml + Glucose 5%
Compatible 100 UI/ml + injectionMidazolam hydrochloride 5 mg/ml
injectionHuman albumin Various
Compatible 250 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionHydralazine hydrochloride Antihypertensive
Compatible 20 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionHydromorphone hydrochloride Analgesic
Compatible 10 mg/ml + injectionLevosimendan 2,5 mg/ml
injectionImipenem - cilastatin sodium Antibiotic
Incompatible 50 mg/ml + injectionCefoxitin sodium 100 mg/ml
injectionInsulin Glucose-lowering
Incompatible 100 UI/ml + injectionDopamine hydrochloride 3,2 mg/ml
injectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0,2 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionKetamine hydrochloride General anesthetic
Compatible 50 mg/ml + injectionAlprostadil 500 µg/ml
Incompatible 50 mg/ml + injectionAminophylline 25 mg/ml
Compatible 50 mg/ml + injectionCiclosporin 50 mg/ml
Incompatible 50 mg/ml + injectionDexamethasone sodium phosphate 4 mg/ml
Compatible 50 mg/ml + injectionDexmedetomidine 100 µg/ml
Compatible 50 mg/ml + injectionEsmolol hydrochloride 10 mg/ml
Compatible 50 mg/ml + injectionIsoprenaline hydrochloride 0,2 mg/ml
Compatible 50 mg/ml + injectionLorazepam 4 mg/ml
Compatible 50 mg/ml + injectionNicardipine hydrochloride 0,2 mg/ml
Incompatible 50 mg/ml + injectionNitroglycerin 5 mg/ml
Compatible 50 mg/ml + injectionNorepinephrine bitartrate 1 mg/ml
Compatible 50 mg/ml + injectionOndansetron hydrochloride 2 mg/ml
Compatible 50 mg/ml + injectionPiperacillin sodium 200 mg/ml
Compatible 50 mg/ml + injectionSalbutamol sulfate 1 mg/ml
Compatible 50 mg/ml + injectionSufentanil citrate 0,05 mg/ml
Compatible 50 mg/ml + injectionVasopressin 20 UI/ml
injectionLevosimendan Various
Compatible 2.5 mg/ml + injectionDexmedetomidine 100 µg/ml
Compatible 2,5 mg/ml + injectionEpinephrine hydrochloride 1000 µg/ml
Compatible 2,5 mg/ml + injectionFentanyl citrate 50 µg/ml
Compatible 2,5 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 2,5 mg/ml + injectionHydromorphone hydrochloride 10 mg/ml
Compatible 2,5 mg/ml + injectionMidazolam hydrochloride 5 mg/ml
Compatible 2,5 mg/ml + injectionMilrinone lactate 1 mg/ml
Compatible 2,5 mg/ml + injectionMorphine sulfate 50 mg/ml
injectionLorazepam Anxiolytic
Compatible 4 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMagnesium sulfate Electrolyte
Incompatible 500 mg/ml + injectionPotassium phosphate 3 mmol/ml
Incompatible 500 mg/ml + injectionSodium Phosphate 3 mmol/ml
injectionMeropenem Antibiotic
Compatible 50 mg/ml + injectionAmikacin sulfate 250 mg/ml
Compatible 50 mg/ml + injectionAztreonam 100 mg/ml
Compatible 50 mg/ml + injectionCeftazidime 100 mg/ml
Compatible 50 mg/ml + injectionTobramycin sulfate 40 mg/ml
injectionMicafungin Antifungal
Incompatible 20 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + injectionHeparin sodium 100 UI/ml
Compatible 5 mg/ml + injectionLevosimendan 2,5 mg/ml
injectionMilrinone lactate Cardiotonic
Compatible 1 mg/ml + injectionAlprostadil 500 µg/ml
Compatible 1 mg/ml + injectionDexmedetomidine 100 µg/ml
Compatible 1 mg/ml + injectionEsmolol hydrochloride 10 mg/ml
Compatible 1 mg/ml + injectionLevosimendan 2,5 mg/ml
injectionMorphine sulfate Analgesic
Compatible 50 mg/ml + injectionLevosimendan 2,5 mg/ml
injectionN-acetylcysteine Antidote
Compatible 200 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionNicardipine hydrochloride Vasodilator
Compatible 0,2 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 1 mg/ml + injectionKetamine hydrochloride 50 mg/ml
Compatible 1 mg/ml + injectionSufentanil citrate 0,05 mg/ml
injectionOndansetron hydrochloride Antiemetic
Compatible 2 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionOxytocin Various
Incompatible 10 UI/ml + injectionRemifentanil hydrochloride 1000 µg/ml
injectionPenicillin G sodium Antibiotic
Compatible 0,5 MUI/ml + injectionDexmedetomidine 100 µg/ml
injectionPhentolamine mesylate Vasodilator
Compatible 5 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionPiperacillin sodium Antibiotic
Compatible 200 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPotassium chloride Electrolyte
Compatible 2 mEq/l + injectionAmpicillin sodium 100 mg/ml
Compatible 2 mEq/l + injectionDimenhydrinate 10 mg/ml
injectionPotassium phosphate Electrolyte
Incompatible 3 mmol/ml + injectionMagnesium sulfate 500 mg/ml
Incompatible 3 mmol/ml + injectionSodium bicarbonate 84 mg/ml
injectionRemifentanil hydrochloride Analgesic
Incompatible 1000 µg/ml + injectionOxytocin 10 UI/ml
injectionSalbutamol sulfate Beta-stimulant
Compatible 1 mg/ml + injectionDexmedetomidine 100 µg/ml
Compatible 1 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionPotassium phosphate 3 mmol/ml
injectionSodium Phosphate Electrolyte
Incompatible 3 mmol/ml + injectionMagnesium sulfate 500 mg/ml
injectionSufentanil citrate Analgesic
Compatible 0,05 mg/ml + injectionKetamine hydrochloride 50 mg/ml
Compatible 0,05 mg/ml + injectionNorepinephrine bitartrate 1 mg/ml
injectionThiamine hydrochloride Vitamin
Compatible 100 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + injectionMeropenem 50 mg/ml
injectionTranexamic acid Anti-bleeding
Compatible 100 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionValproic acid Antiepileptic
Compatible 100 mg/ml + injectionDexmedetomidine 100 µg/ml
injectionVasopressin Hormone
Compatible 20 UI/ml + injectionKetamine hydrochloride 50 mg/ml

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