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Type : Journal
Icone.pdf
2972Ko
Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : D'Huart E, Vigneron J, Demoré B.
Title : Physical Compatibility of Intravenous Drugs Commonly Used in Intensive Care Units: An Observational Study and Physical Compatibility Laboratory Tests on Anti-Infective Drugs
Reference : Pharmaceutical Technology in Hospital Pharmacy ;4,1:29-40 2019
Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
injectionAmoxicillin sodium Antibiotic
Compatible 20.83 & 83.3 mg/ml + injectionHeparin sodium 208 UI/ml + Sodium chloride 0,9%
Compatible 20.83 & 83.3 mg/ml + injectionInsulin 1 UI/ml + Sodium chloride 0,9%
Incompatible 20.83 mg/ml + injectionMagnesium sulfate 6 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 20.83 mg/ml + injectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 20.83 mg/ml + injectionPyridoxine hydrochloride 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 20.83 mg/ml + injectionThiamine hydrochloride 0.2 mg/ml + Glucose 5%
Incompatible 20.83 mg/ml + injectionVancomycin hydrochloride 31.25 mg/ml + Glucose 5%
injectionAmphotericin B liposomale Antifungal
Incompatible 1.16 mg/ml + injectionVancomycin hydrochloride 10 & 62.5 & 83.3 mg/ml + Glucose 5%
injectionCefazolin sodium Antibiotic
Incompatible 41.6 mg/ml + injectionCo-trimoxazole 3.2/0.64 & 80/16 mg/ml + Glucose 5%
Compatible 41.6 mg/ml + injectionLevetiracetam 5.21 & 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 41.6 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
Incompatible 41.6 mg/ml + injectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 41.6 mg/ml + injectionPantoprazole sodium 4 mg/ml + NaCl 0,9% or Glucose 5%
injectionCefepime dihydrochloride Antibiotic
Compatible 83.3 mg/ml + injectionDaptomycin 21 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + injectionThiamine hydrochloride 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + injectionVoriconazole 8 mg/ml + Glucose 5%
injectionCefotaxime sodium Antibiotic
Compatible 41.6 & 125 mg/ml + injectionHeparin sodium 208 UI/ml + NaCl 0,9% or Glucose 5%
Incompatible 83.3 mg/ml + injectionHydrocortisone sodium succinate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + injectionInsulin 1 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + injectionLevetiracetam 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + injectionOrnidazole 31.25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + injectionThiamine hydrochloride 0.4 mg/ml + Glucose 5%
injectionCo-trimoxazole Antibiotic
Incompatible 3.2/0.64 & 80/16 mg/ml + injectionCefazolin sodium 41.6 mg/ml + Glucose 5%
Incompatible 3.2/0.64 & 80/16 mg/ml + injectionHeparin sodium 208 UI/ml + NaCl 0,9% or Glucose 5%
Incompatible 3.2/0.64 & 80/16 mg/ml + injectionInsulin 1 UI/ml + NaCl 0,9% or Glucose 5%
injectionDaptomycin Antibiotic
Compatible 21 mg/ml + injectionCefepime dihydrochloride 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 21 mg/ml + injectionThiamine hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionThiamine hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
injectionGentamicin sulfate Antibiotic
Compatible 4.17 mg/ml + injectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
injectionHeparin sodium Anticoagulant
Compatible 208 UI/ml + injectionAmoxicillin sodium 20.83 & 83.3 mg/ml + Sodium chloride 0,9%
Compatible 208 UI/ml + injectionCefotaxime sodium 41.6 & 125 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 208 UI/ml + injectionCo-trimoxazole 3.2/0.64 & 80/16 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 208 UI/ml + injectionOrnidazole 31.25 mg/ml + Sodium chloride 0,9%
Compatible 208 UI/ml + injectionSpiramycine adipate 0.0625 MUI/ml + Sodium chloride 0,9%
Compatible 208 UI/ml + injectionVoriconazole 8 mg/ml + NaCl 0,9% or Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 2 mg/ml + injectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
injectionInsulin Glucose-lowering
Compatible 1 UI/ml + injectionAmoxicillin sodium 20.83 & 83.3 mg/ml + Sodium chloride 0,9%
Compatible 1 UI/ml + injectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 1 UI/ml + injectionCo-trimoxazole 3.2/0.64 & 80/16 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 1 UI/ml + injectionLinezolid 2 mg/ml + Sodium chloride 0,9%
Compatible 1 UI/ml + injectionOrnidazole 31.25 mg/ml + Sodium chloride 0,9%
Compatible 1 UI/ml + injectionPiperacillin sodium / tazobactam 166/20.83 mg/ml + NaCl 0,9% or Glucose 5%
injectionLevetiracetam Antiepileptic
Compatible 5.21 & 20.83 mg/ml + injectionCefazolin sodium 41.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 20.83 mg/ml + injectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 20.83 mg/ml + injectionPiperacillin sodium / tazobactam 166/20.83 mg/ml + NaCl 0,9% or Glucose 5%
injectionLevofloxacine Antibiotic
Compatible 5 mg/ml + injectionCefazolin sodium 41.6 mg/ml + Glucose 5%
injectionLinezolid Antibiotic
Compatible 2 mg/ml + injectionInsulin 1 UI/ml + Sodium chloride 0,9%
injectionMagnesium sulfate Electrolyte
Incompatible 6 mg/ml + injectionAmoxicillin sodium 20.83 mg/ml + NaCl 0,9% or Glucose 5%
injectionNefopam Analgesic
Incompatible 0.16 mg/ml + injectionAmoxicillin sodium 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.16 mg/ml + injectionCefazolin sodium 41.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.16 mg/ml + injectionGentamicin sulfate 4.17 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.16 mg/ml + injectionVancomycin hydrochloride 31.25 mg/ml + NaCl 0,9% or Glucose 5%
injectionOrnidazole Antibiotic
Compatible 31.25 mg/ml + injectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 31.25 mg/ml + injectionHeparin sodium 208 UI/ml + Sodium chloride 0,9%
Compatible 31.25 mg/ml + injectionInsulin 1 UI/ml + Sodium chloride 0,9%
injectionPantoprazole sodium Proton pump inhibitor
Compatible 4 mg/ml + injectionCefazolin sodium 41.6 mg/ml + NaCl 0,9% or Glucose 5%
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 166/20.83 mg/ml + injectionInsulin 1 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 166/20.83 mg/ml + injectionLevetiracetam 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 166/20.83 mg/ml + injectionThiamine hydrochloride 0.4 mg/ml + Glucose 5%
injectionPyridoxine hydrochloride Vitamin
Incompatible 0.5 mg/ml + injectionAmoxicillin sodium 20.83 mg/ml + NaCl 0,9% or Glucose 5%
injectionSpiramycine adipate Antibiotic
Compatible 0.0625 MUI/ml + injectionHeparin sodium 208 UI/ml + Sodium chloride 0,9%
injectionThiamine hydrochloride Vitamin
Incompatible 0.2 mg/ml + injectionAmoxicillin sodium 20.83 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefepime dihydrochloride 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.4 mg/ml + injectionCefotaxime sodium 83.3 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionDaptomycin 21 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
Compatible 0.4 mg/ml + injectionPiperacillin sodium / tazobactam 166/20.83 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionVoriconazole 8 mg/ml + NaCl 0,9% or Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Incompatible 31.25 mg/ml + injectionAmoxicillin sodium 20.83 mg/ml + Glucose 5%
Incompatible 10 & 62.5 & 83.3 mg/ml + injectionAmphotericin B liposomale 1.16 mg/ml + Glucose 5%
Compatible 31.25 mg/ml + injectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
injectionVoriconazole Antifungal
Compatible 8 mg/ml + injectionCefepime dihydrochloride 83.3 mg/ml + Glucose 5%
Compatible 8 mg/ml + injectionHeparin sodium 208 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 8 mg/ml + injectionThiamine hydrochloride 0.2 mg/ml + NaCl 0,9% or Glucose 5%
  Mentions Légales