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Type : Journal
Icone.pdf
2972Ko
Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : D'Huart E, Vigneron J, Demoré B.
Title : Physical Compatibility of Intravenous Drugs Commonly Used in Intensive Care Units: An Observational Study and Physical Compatibility Laboratory Tests on Anti-Infective Drugs
Reference : Pharmaceutical Technology in Hospital Pharmacy ;4,1:29-40 2019
Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
InjectionAmoxicillin sodium Antibiotic
Compatible 20.83 & 83.3 mg/ml + InjectionHeparin sodium 208 UI/ml + Sodium chloride 0,9%
Compatible 20.83 & 83.3 mg/ml + InjectionInsulin 1 UI/ml + Sodium chloride 0,9%
Incompatible 20.83 mg/ml + InjectionMagnesium sulfate 6 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 20.83 mg/ml + InjectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 20.83 mg/ml + InjectionPyridoxine hydrochloride 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 20.83 mg/ml + InjectionThiamine hydrochloride 0.2 mg/ml + Glucose 5%
Incompatible 20.83 mg/ml + InjectionVancomycin hydrochloride 31.25 mg/ml + Glucose 5%
InjectionAmphotericin B liposomale Antifungal
Incompatible 1.16 mg/ml + InjectionVancomycin hydrochloride 10 & 62.5 & 83.3 mg/ml + Glucose 5%
InjectionCefazolin sodium Antibiotic
Incompatible 41.6 mg/ml + InjectionCo-trimoxazole 3.2/0.64 & 80/16 mg/ml + Glucose 5%
Compatible 41.6 mg/ml + InjectionLevetiracetam 5.21 & 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 41.6 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
Incompatible 41.6 mg/ml + InjectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 41.6 mg/ml + InjectionPantoprazole sodium 4 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCefepime dihydrochloride Antibiotic
Compatible 83.3 mg/ml + InjectionDaptomycin 21 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + InjectionThiamine hydrochloride 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + InjectionVoriconazole 8 mg/ml + Glucose 5%
InjectionCefotaxime sodium Antibiotic
Compatible 41.6 & 125 mg/ml + InjectionHeparin sodium 208 UI/ml + NaCl 0,9% or Glucose 5%
Incompatible 83.3 mg/ml + InjectionHydrocortisone sodium succinate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + InjectionInsulin 1 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + InjectionLevetiracetam 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + InjectionOrnidazole 31.25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 83.3 mg/ml + InjectionThiamine hydrochloride 0.4 mg/ml + Glucose 5%
InjectionCo-trimoxazole Antibiotic
Incompatible 3.2/0.64 & 80/16 mg/ml + InjectionCefazolin sodium 41.6 mg/ml + Glucose 5%
Incompatible 3.2/0.64 & 80/16 mg/ml + InjectionHeparin sodium 208 UI/ml + NaCl 0,9% or Glucose 5%
Incompatible 3.2/0.64 & 80/16 mg/ml + InjectionInsulin 1 UI/ml + NaCl 0,9% or Glucose 5%
InjectionDaptomycin Antibiotic
Compatible 21 mg/ml + InjectionCefepime dihydrochloride 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 21 mg/ml + InjectionThiamine hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionThiamine hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
InjectionGentamicin sulfate Antibiotic
Compatible 4.17 mg/ml + InjectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
InjectionHeparin sodium Anticoagulant
Compatible 208 UI/ml + InjectionAmoxicillin sodium 20.83 & 83.3 mg/ml + Sodium chloride 0,9%
Compatible 208 UI/ml + InjectionCefotaxime sodium 41.6 & 125 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 208 UI/ml + InjectionCo-trimoxazole 3.2/0.64 & 80/16 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 208 UI/ml + InjectionOrnidazole 31.25 mg/ml + Sodium chloride 0,9%
Compatible 208 UI/ml + InjectionSpiramycine adipate 0.0625 MUI/ml + Sodium chloride 0,9%
Compatible 208 UI/ml + InjectionVoriconazole 8 mg/ml + NaCl 0,9% or Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 2 mg/ml + InjectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
InjectionInsulin Glucose-lowering
Compatible 1 UI/ml + InjectionAmoxicillin sodium 20.83 & 83.3 mg/ml + Sodium chloride 0,9%
Compatible 1 UI/ml + InjectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 1 UI/ml + InjectionCo-trimoxazole 3.2/0.64 & 80/16 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 1 UI/ml + InjectionLinezolid 2 mg/ml + Sodium chloride 0,9%
Compatible 1 UI/ml + InjectionOrnidazole 31.25 mg/ml + Sodium chloride 0,9%
Compatible 1 UI/ml + InjectionPiperacillin sodium / tazobactam 166/20.83 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLevetiracetam Antiepileptic
Compatible 5.21 & 20.83 mg/ml + InjectionCefazolin sodium 41.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 20.83 mg/ml + InjectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 20.83 mg/ml + InjectionPiperacillin sodium / tazobactam 166/20.83 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLevofloxacine Antibiotic
Compatible 5 mg/ml + InjectionCefazolin sodium 41.6 mg/ml + Glucose 5%
InjectionLinezolid Antibiotic
Compatible 2 mg/ml + InjectionInsulin 1 UI/ml + Sodium chloride 0,9%
InjectionMagnesium sulfate Electrolyte
Incompatible 6 mg/ml + InjectionAmoxicillin sodium 20.83 mg/ml + NaCl 0,9% or Glucose 5%
InjectionNefopam Analgesic
Incompatible 0.16 mg/ml + InjectionAmoxicillin sodium 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.16 mg/ml + InjectionCefazolin sodium 41.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.16 mg/ml + InjectionGentamicin sulfate 4.17 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.16 mg/ml + InjectionVancomycin hydrochloride 31.25 mg/ml + NaCl 0,9% or Glucose 5%
InjectionOrnidazole Antibiotic
Compatible 31.25 mg/ml + InjectionCefotaxime sodium 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 31.25 mg/ml + InjectionHeparin sodium 208 UI/ml + Sodium chloride 0,9%
Compatible 31.25 mg/ml + InjectionInsulin 1 UI/ml + Sodium chloride 0,9%
InjectionPantoprazole sodium Proton pump inhibitor
Compatible 4 mg/ml + InjectionCefazolin sodium 41.6 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPiperacillin sodium / tazobactam Antibiotic
Compatible 166/20.83 mg/ml + InjectionInsulin 1 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 166/20.83 mg/ml + InjectionLevetiracetam 20.83 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 166/20.83 mg/ml + InjectionThiamine hydrochloride 0.4 mg/ml + Glucose 5%
InjectionPyridoxine hydrochloride Vitamin
Incompatible 0.5 mg/ml + InjectionAmoxicillin sodium 20.83 mg/ml + NaCl 0,9% or Glucose 5%
InjectionSpiramycine adipate Antibiotic
Compatible 0.0625 MUI/ml + InjectionHeparin sodium 208 UI/ml + Sodium chloride 0,9%
InjectionThiamine hydrochloride Vitamin
Incompatible 0.2 mg/ml + InjectionAmoxicillin sodium 20.83 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefepime dihydrochloride 83.3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.4 mg/ml + InjectionCefotaxime sodium 83.3 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionDaptomycin 21 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
Compatible 0.4 mg/ml + InjectionPiperacillin sodium / tazobactam 166/20.83 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionVoriconazole 8 mg/ml + NaCl 0,9% or Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Incompatible 31.25 mg/ml + InjectionAmoxicillin sodium 20.83 mg/ml + Glucose 5%
Incompatible 10 & 62.5 & 83.3 mg/ml + InjectionAmphotericin B liposomale 1.16 mg/ml + Glucose 5%
Compatible 31.25 mg/ml + InjectionNefopam 0.16 mg/ml + NaCl 0,9% or Glucose 5%
InjectionVoriconazole Antifungal
Compatible 8 mg/ml + InjectionCefepime dihydrochloride 83.3 mg/ml + Glucose 5%
Compatible 8 mg/ml + InjectionHeparin sodium 208 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 8 mg/ml + InjectionThiamine hydrochloride 0.2 mg/ml + NaCl 0,9% or Glucose 5%
  Mentions Légales