Last update :
19/11/2024
References   References 3976  
Type : Journal
Web link : https://doi.org/10.2146/ajhp170111
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Research teams : Marseille - La Timone University Teaching Hospital, Pharmacy Department
Authors : Du Repaire T, Vigne P, Guedon A, Gauthier-Villano L, Bertault Peres P, Pourroy B.
Title : Visual compatibility of blinatumomab with selected co-administrated drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 74,16 : 1217-1218 2017

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAlizapride hydrochloride Antiemetic
Incompatible 0.5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionAmphotericin B liposomale Antifungal
Compatible 1 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionBlinatumomab Anticancer drug
Incompatible 0.125 & 0.375 µg/ml + injectionAlizapride hydrochloride 0.5 mg/ml + Sodium chloride 0,9%
Compatible 0.125 & 0.375 µg/ml + injectionAmphotericin B liposomale 1 mg/ml + Sodium chloride 0,9%
Compatible 0.125 & 0.375 µg/ml + injectionCaffeine citrate 25 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionCaspofungin acetate 0.20 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionCeftazidime 34.5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionCeftriaxone disodium 50 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionClonazepam 0.02 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionCloxacillin sodium 8.6 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionCo-trimoxazole 3.2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionDaptomycin 6.1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionDexamethasone sodium phosphate 0.19 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionFurosemide 2.9 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionHeparin sodium 192.3 UI/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionHuman albumin 100 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionHuman albumin 100 mg/ml + Sodium chloride 0,9%
Compatible 0.125 & 0.375 µg/ml + injectionHydrocortisone sodium succinate 0.98 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionHydroxyzine dihydrochloride 0.4 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionImipenem - cilastatin sodium 5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionMeropenem 8.3 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionMetronidazole 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionMidazolam hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionMorphine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionNalbuphine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionNaloxone hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionNefopam 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionOmeprazole sodium 0.4 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionOndansetron hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionPantoprazole sodium 0.8 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionParacetamol 10 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionPhloroglucinol 5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionPotassium chloride 0.3 mEq/l + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionRasburicase 0.15 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionTeicoplanine 4 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionTranexamic acid 100 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + injectionVancomycin hydrochloride 2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + Parenteral nutrition (binary mixture)
injectionCaffeine citrate Respiratory stimulant
Compatible 25 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionCaspofungin acetate Antifungal
Incompatible 0.20 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionCeftazidime Antibiotic
Incompatible 34.5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionCeftriaxone disodium Antibiotic
Incompatible 50 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionCiprofloxacin lactate Antibiotic
Incompatible 2 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionClonazepam Antiepileptic
Incompatible 0.02 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionCloxacillin sodium Antibiotic
Incompatible 8.6 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionCo-trimoxazole Antibiotic
Incompatible 3.2 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionDaptomycin Antibiotic
Incompatible 6.1 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 0.19 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Incompatible 2.9 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Incompatible 192.3 UI/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionHuman albumin Various
Incompatible 100 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
Incompatible 100 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 0.98 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionHydroxyzine dihydrochloride Anxiolytic
Incompatible 0.4 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionImipenem - cilastatin sodium Antibiotic
Incompatible 5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionMeropenem Antibiotic
Incompatible 8.3 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionMetronidazole Antiparasitic
Incompatible 2.5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionMidazolam hydrochloride Anxiolytic
Incompatible 1 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionMorphine hydrochloride Analgesic
Incompatible 1 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionNalbuphine hydrochloride Antidote
Incompatible 1 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionNaloxone hydrochloride Antidote
Incompatible 0.2 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionNefopam Analgesic
Incompatible 2.5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionOmeprazole sodium Proton pump inhibitor
Incompatible 0.4 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionOndansetron hydrochloride Antiemetic
Incompatible 0.2 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionPantoprazole sodium Proton pump inhibitor
Incompatible 0.8 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionParacetamol Analgesic
Incompatible 10 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionPhloroglucinol  Antispasmodic
Incompatible 5 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionPotassium chloride Electrolyte
Incompatible 0.3 mEq/l + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionRasburicase Various
Incompatible 0.15 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionTeicoplanine Antibiotic
Incompatible 4 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionTranexamic acid Anti-bleeding
Incompatible 100 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
injectionVancomycin hydrochloride Antibiotic
Incompatible 2 mg/ml + injectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%

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