Type : |
Journal |
|
Research teams : |
Utrecht - Faculty of pharmacy, State university of Utrecht |
Authors : |
Beijnen JH, van Gijn R, Challa EE, Kaijser GP, Underberg WJM. |
Title : |
Chemical stability of two sterile, parenteral formulations of cyclophosphamide (Endoxan) after reconstitution and dilution in commonly used infusion fluids. |
Reference : |
J Parenter Sci Technol ; 46: 111-116. 1992 |
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Level of Evidence : |
|
Physical stability : |
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Chemical stability : |
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Other methods : |
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Comments : |
Degradation products quantified but not identified |
|
List of drugs
Cyclophosphamide
|
![Anticancer drug Anticancer drug](./images/Picto.486.jpg) |
![Factors which affect stability Factors which affect stability](./images/Picto.594.jpg) |
![Temperature Temperature](./images/Picto.679.jpg) |
|
![Induces Induces](./images/Picto.659.gif) |
![Degradation Degradation](./images/Picto.678.gif) |
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Glass Glass](./images/Picto.532.jpg) |
![Water for Injection Water for Injection](./images/Picto.545.gif) |
20 mg/ml |
4°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Glass Glass](./images/Picto.532.jpg) |
![NaCl 0,9% or Glucose 5% NaCl 0,9% or Glucose 5%](./images/Picto.546.gif) |
1 mg/ml |
25°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Glass Glass](./images/Picto.532.jpg) |
![NaCl 0,9% or Glucose 5% NaCl 0,9% or Glucose 5%](./images/Picto.546.gif) |
1 mg/ml |
4°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyvinyl chloride Polyvinyl chloride](./images/Picto.533.gif) |
![Water for Injection Water for Injection](./images/Picto.545.gif) |
20 mg/ml |
4°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyvinyl chloride Polyvinyl chloride](./images/Picto.533.gif) |
![NaCl 0,9% or Glucose 5% NaCl 0,9% or Glucose 5%](./images/Picto.546.gif) |
1 mg/ml |
4°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyvinyl chloride Polyvinyl chloride](./images/Picto.533.gif) |
![Sodium chloride 0,9% Sodium chloride 0,9%](./images/Picto.547.gif) |
1 mg/ml |
25°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyvinyl chloride Polyvinyl chloride](./images/Picto.533.gif) |
![Glucose 5% Glucose 5%](./images/Picto.548.gif) |
1 mg/ml |
25°C |
![Protect from light Protect from light](./images/Picto.526.jpg) |
2 |
![Day Day](./images/Picto.542.gif) |
|
|
|
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