Last update :
08/11/2024
References   References 78  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/47/9/2043

Research teams : Athens - University of Georgia, College of Pharmacy
Authors : Stewart JT, Warren FW, Johnson SM, Galante LJ.
Title : Stability of ranitidine in intravenous admixtures stored frozen, refrigerated, and at room temperature.
Reference : Am J Hosp Pharm ; 47: 2043-2046. 1990

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionRanitidine hydrochloride Antihistamine (H2)
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 1 & 2 mg/ml -20°C Protect from light
60 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 1 & 2 mg/ml 25°C Light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 1 & 2 mg/ml 4°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride Glucose 10% 0,5 & 1 & 2 mg/ml -20°C Protect from light
60 Day
Stability in solutions Polyvinyl chloride Glucose 10% 0,5 & 1 & 2 mg/ml 25°C Light
7 Day
Stability in solutions Polyvinyl chloride Glucose 10% 0,5 & 1 & 2 mg/ml 4°C Protect from light
30 Day

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