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References   References 4428  
Type : Journal
Web link : https://doi.org/10.5863/1551-6776-9.2.126
Research teams : Memphis - University of Tennessee, College of Pharmacy
Authors : Rashed S.M, Sweatman T.W, Thoma L, Hovinga C.A, Phelps S.J.
Title : Chemical Compatibility of Depacon® with Medications Frequently Administered by Intravenous Y-Site Delivery in Patients with Epilepsy or Head Trauma.
Reference : J Pediatr Pharmacol Ther ; 9, 2: 126-132. 2004
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
injectionAtracurium besylate Curarimimetic
Compatible 0.2 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.64 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionFosphenytoin sodium Antiepileptic
Compatible + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionLorazepam Anxiolytic
Compatible 1 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionMannitol Various
Compatible 150 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Incompatible 2 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionPentobarbital sodium General anesthetic
Compatible 5 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionThiopental sodium General anesthetic
Compatible 25 mg/ml + injectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
injectionValproic acid Antiepileptic
Compatible 2 & 20 mg/ml + injectionAtracurium besylate 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionDexamethasone sodium phosphate 0.64 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 & 20 mg/ml + injectionDiazepam 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionFosphenytoin sodium + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionLorazepam 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionMagnesium sulfate 100 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionMannitol 150 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 & 20 mg/ml + injectionMidazolam hydrochloride 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionPentobarbital sodium 5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 & 20 mg/ml + injectionPhenytoin sodium 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionRanitidine hydrochloride 25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + injectionThiopental sodium 25 mg/ml + NaCl 0,9% or Glucose 5%
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