Last update :
27/11/2024
References   References 1490  
Type : Journal

Research teams : Bronx - Bronx VA Medical Center, Surgical Intensive Care Unit
Authors : Halpern NA, Colucci RD, Alicea M, Greenstein R.
Title : The compatibility of nicardipine hydrochloride injection with various ICU medications during simulated Y-site injection.
Reference : Int J Pharm Clin Pharmacol Ther Tox ; 27: 250-254. 1989

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmikacin sulfate Antibiotic
Compatible 2 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionAminophylline Various
Compatible 1 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionAmpicillin sodium Antibiotic
Incompatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Incompatible 15 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionAztreonam Antibiotic
Compatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionButorphanol tartrate Analgesic
Compatible 0.4 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCalcium gluconate Electrolyte
Compatible 19.8 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCefoperazone sodium Antibiotic
Incompatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCeftazidime Antibiotic
Compatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCeftizoxime sodium Antibiotic
Compatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionChloramphenicol sodium succinate Antibiotic
Compatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 3 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionClindamycin phosphate Antibiotic
Compatible 9 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionCo-trimoxazole Antibiotic
Compatible 0.8/1.6 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 1.6 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionEnalaprilate Antihypertensive
Compatible 0.5 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 0.2 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 2 µg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 0.8 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionHeparin sodium Anticoagulant
Compatible 40 UI/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionHetastarch Various
Compatible 60 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 2 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionLabetalol hydrochloride Beta-blocker
Compatible 1 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionLidocaine hydrochloride Local anesthetic
Compatible 4 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionMagnesium sulfate Electrolyte
Compatible 600 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 0.8 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 0.2 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionNafcillin sodium Antibiotic
Compatible 10 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionNicardipine hydrochloride Vasodilator
Compatible 0.1 mg/ml + injectionAmikacin sulfate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionAminophylline 1 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.1 mg/ml + injectionAmpicillin sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.1 mg/ml + injectionAmpicillin sodium - sulbactam sodium 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionAztreonam 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionButorphanol tartrate 0.4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionCalcium gluconate 19.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionCefazolin sodium 20 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.1 mg/ml + injectionCefoperazone sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionCeftazidime 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionCeftizoxime sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionChloramphenicol sodium succinate 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionCimetidine hydrochloride 3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionClindamycin phosphate 9 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionCo-trimoxazole 0.8/1.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionDobutamine hydrochloride 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionDopamine hydrochloride 1.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionEnalaprilate 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionErythromycin lactobionate 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionFamotidine 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionFentanyl citrate 2 µg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionGentamicin sulfate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionHeparin sodium 40 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionHetastarch 60 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionHydrocortisone sodium succinate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionLabetalol hydrochloride 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionLidocaine hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionMagnesium sulfate 600 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionMethylprednisolone sodium succinate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionMetronidazole 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionMorphine sulfate 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionNafcillin sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionNitroprusside sodium 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionPenicillin G potassium 0.05 MUI/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionPiperacillin sodium 12 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionPotassium chloride 400 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionPotassium phosphate 0.44 mmol/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionRanitidine hydrochloride 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionTobramycin sulfate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + injectionVancomycin hydrochloride 5 mg/ml + NaCl 0,9% or Glucose 5%
injectionNitroprusside sodium Vasodilator
Compatible 0.2 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionPenicillin G potassium Antibiotic
Compatible 0.05 MUI/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionPiperacillin sodium Antibiotic
Compatible 12 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 400 mEq/l + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionPotassium phosphate Electrolyte
Compatible 0.44 mmol/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0.5 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 0.8 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + injectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%

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