Last update :
29/10/2024
Anticancer drug   Blinatumomab  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Blincyto Argentina, Australia, Austria, Belgium, Brazil, Chile, Denmark, France, Germany, Great Britain, Hungary, Ireland, Italy, Japan, Luxembourg, Mexico, Norway, Peru, Romania, Slovenia, Spain, Sweden, Switzerland, United States of America
Compatibility   injection   Compatibility : Blinatumomab              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
Parenteral nutrition (binary mixture) 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Alizapride hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 3976
Compatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Amphotericin B liposomale 1 mg/ml
Sodium chloride 0,9% 3976
Compatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Caffeine citrate 25 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Caspofungin acetate 0.20 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Ceftazidime 34.5 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Ceftriaxone disodium 50 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Ciprofloxacin lactate 2 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Clonazepam 0.02 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Cloxacillin sodium 8.6 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Co-trimoxazole 3.2 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Daptomycin 6.1 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Dexamethasone sodium phosphate 0.19 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Furosemide 2.9 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Heparin sodium 192.3 UI/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Human albumin 100 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Human albumin 100 mg/ml
Sodium chloride 0,9% 3976
Compatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Hydrocortisone sodium succinate 0.98 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Hydroxyzine dihydrochloride 0.4 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Imipenem - cilastatin sodium 5 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Meropenem 8.3 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Metronidazole 2.5 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Midazolam hydrochloride 1 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Morphine hydrochloride 1 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Nalbuphine hydrochloride 1 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Naloxone hydrochloride 0.2 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Nefopam 2.5 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Omeprazole sodium 0.4 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Ondansetron hydrochloride 0.2 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Pantoprazole sodium 0.8 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Paracetamol 10 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Phloroglucinol 5 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Potassium chloride 0.3 mEq/l
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Rasburicase 0.15 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Teicoplanine 4 mg/ml
Sodium chloride 0,9% 3976
Unspecified incompatibility Incompatible
injection Blinatumomab
injection Temocilline
2296
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Tranexamic acid 100 mg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
injection Blinatumomab 0.125 & 0.375 µg/ml
injection Vancomycin hydrochloride 2 mg/ml
Sodium chloride 0,9% 3976

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