Last update :
06/05/2025
Antiemetic   Metoclopramide hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Afipran Iceland, Norway
Aristopramida Brazil
Cerucal Hungary
Clopan Ecuador
Clopram Tunisia, United Arab Emirates
Disgradon Argentina
Doperan Tunisia
Maxolon Australia, Great Britain, Ireland
Meclomid Mexico
Meclonir Colombia, Ecuador
Meclop Egypt, Mexico
Meclopram Egypt
Metoclox Ecuador
Metogastron Austria
Metoplon Turkey
Metpamid Turkey
Paspertin Austria, Switzerland
Plasil Brazil, Colombia, Italy
Plemazol Egypt
Pramadin Venezuela
Pramotil Mexico
Primperan Belgium, Colombia, Denmark, Ecuador, Egypt, Finland, France, Greece, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, Peru, Portugal, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates, Venezuela
Primsel Turkey
Reglan Slovenia, United States of America
Stability of mixtures   injection   Stability of mixtures : Metoclopramide hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
42 Day
Protect from light 1495
Level of evidence B
Glass Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
189 Day
Protect from light 1495
Level of evidence B
Glass Glucose 5% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
14 Day
Protect from light 1495
Level of evidence B
Glass Glucose 5% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
35 Day
Protect from light 1495
Level of evidence B
Glass None 25 mg/ml
injection   Metoclopramide hydrochloride   
injection   Palonosetron hydrochloride 25 µg/ml
25°C
4 Hour
Not specified 2179
Level of evidence A+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0.15 mg/ml
injection   Metoclopramide hydrochloride   
injection   Pethidine hydrochloride 7.35 mg/ml
32°C
48 Hour
Not specified 930
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
42 Day
Protect from light 1495
Level of evidence B
Polyvinyl chloride Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
189 Day
Protect from light 1495
Level of evidence B
Polyethylene Glucose 5% 0,1 mg/ml
injection   Metoclopramide hydrochloride   
injection   Tramadol hydrochloride 1 mg/ml
4°C
32 Day
Protect from light 3082
Level of evidence A+
Polypropylen Syringe Water for Injection 0,7 mg/ml
injection   Metoclopramide hydrochloride   
injection   Midazolam hydrochloride 0,6 mg/ml
injection   Fentanyl citrate 40 µg/ml
32°C
10 Day
Protect from light 1405
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
22°C
42 Day
Protect from light 1495
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 2,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Ondansetron hydrochloride 1 mg/ml
23°C
24 Hour
Light 815
Level of evidence C+
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Haloperidol lactate 0,5 mg/ml
injection   Hydromorphone hydrochloride 10 mg/ml
25°C
96 Hour
Not specified 2166
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Famotidine 0,4 mg/ml
suppository   Ketoprofene   
injection   Hydromorphone hydrochloride 10 mg/ml
25°C
96 Hour
Not specified 2166
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Morphine sulfate 1 mg/ml
4°C
189 Day
Protect from light 1495
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 2,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Ondansetron hydrochloride 1 mg/ml
4°C
24 Hour
Protect from light 815
Level of evidence C+
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml
injection   Metoclopramide hydrochloride   
injection   Famotidine 0,4 mg/ml
injection   Ketorolac tromethamine 1,5 mg/ml
injection   Hydromorphone hydrochloride 10 mg/ml
4°C
96 Hour
Not specified 2166
Not specified NaCl 0,9% or Glucose 5% 0,86 mg/ml
injection   Metoclopramide hydrochloride   
injection   Topotecan 0,028 mg/ml
20°C-23°C
4 Hour
Light 1026
Level of evidence C
Not specified Sodium chloride 0,9% 1,6 mg/ml
injection   Metoclopramide hydrochloride   
injection   Diphenhydramine hydrochloride 2 mg/ml
injection   Dexamethasone sodium phosphate 0,16 mg/ml
25°C
48 Hour
Light 3779
Level of evidence D

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