Last update :
19/11/2024
Analgesic   Ziconotide acetate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Prialt Austria, Denmark, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Ireland, Italy, Japan, Luxembourg, Netherlands, Norway, Poland, Romania, Spain, Sweden, Switzerland, United States of America
Stability of mixtures   injection   Stability of mixtures : Ziconotide acetate     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Polyolefine Sodium chloride 0,9% 0,2 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 2 mg/ml
injection   Ropivacain hydrochloride 6 mg/ml
18-24°C
14 Day
Not specified 3998
Level of evidence D
Polypropylen Syringe Sodium chloride 0,9% 1 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 3,5 mg/ml
injection   Ropivacain hydrochloride 7.5 mg/ml
2-8°C
3 Day
Not specified 3998
Level of evidence D
Polypropylen Syringe Sodium chloride 0,9% 0,2 >> 3 µg/ml
injection   Ziconotide acetate   
injection   Sufentanil citrate 0,003 >>0,045 mg/ml
2-8°C
7 Day
Not specified 4496
Level of evidence D
Polypropylen Syringe Sodium chloride 0,9% 0,2 >> 3 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 0,5 >> 30 mg/ml
2-8°C
7 Day
Not specified 4496
Level of evidence D
Synchromed® Sodium chloride 0,9% 0,5 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 0,5 mg/ml
injection   Ropivacain hydrochloride 0,5 mg/ml
37°C
14 Day
Protect from light 4669
Level of evidence B+
Synchromed® Sodium chloride 0,9% 0,5 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 6 mg/ml
injection   Ropivacain hydrochloride 8,5 mg/ml
37°C
21 Day
Protect from light 4669
Level of evidence B+
Synchromed® Sodium chloride 0,9% 0,5 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 0,5 mg/ml
injection   Ropivacain hydrochloride 8,5 mg/ml
37°C
60 Day
Protect from light 4669
Level of evidence B+
Synchromed® Sodium chloride 0,9% 2 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 0,5 mg/ml
injection   Ropivacain hydrochloride 0,5 mg/ml
37°C
60 Day
Protect from light 4669
Level of evidence B+
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 35 mg/ml
37°C
8 Day
Protect from light 2251
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Baclofen 1,5 mg/ml
37°C
12 Day
Protect from light 2249
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 20 mg/ml
37°C
19 Day
Protect from light 2298
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Hydromorphone hydrochloride 35 mg/ml
37°C
19 Day
Protect from light 2251
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Fentanyl citrate 1 µg/ml
37°C
26 Day
Protect from light 2280
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Sufentanil citrate 1 mg/ml
37°C
33 Day
Protect from light 2280
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 10 mg/ml
37°C
34 Day
Protect from light 2298
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Clonidine hydrochloride 2 mg/ml
37°C
60 Day
Protect from light 2248
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 20 mg/ml
5°C
28 Day
Protect from light 2298
Level of evidence D
Not specified Sodium chloride 0,9% 25 µg/ml
injection   Ziconotide acetate   
injection   Morphine sulfate 10 mg/ml
5°C
60 Day
Protect from light 2298
Level of evidence D
Not specified None 25 µg/ml
injection   Ziconotide acetate   
injection   Bupivacaine hydrochloride 5 mg/ml
37°C
22 Day
Protect from light 2252
Level of evidence B

  Mentions Légales