Ultimo aggiornamento :
19/11/2024
Antibiotico   Meropenem  
Iniezione
Stabilità in soluzione Stabilità in miscela Fattori che influenzano la stabilità Compatibilità metodo di iniezione Bibliografia pdf
   Struttura chimica  

Nome commerciale   Nome commerciale     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acus Chile
Amplium Messico
Anfletec Argentina
Bapentor Messico
Biomerem Venezuela
Klopenem Argentina
Mectinex Chile
Meprim Chile
Merinfec Austria
Merobac Colombia, Ecuador, Perù
Meromax Chile
Meronem Africa del Sud, Arabia Saudita, Belgio, Chile, Colombia, Croazia, Danimarca, Ecuador, Emirati Arabi Uniti, Finlandia, Germania, Gran Bretagna, Grecia, Irlanda, Islanda, Lussemburgo, Norvegia, Paesi Bassi, Perù, Polonia, Portogallo, Romania, Slovenia, Spagna, Svezia, Svizzera, Tailandia, Turchia, Ungheria
Meropen Giappone
Merozan Grecia
Merozem Argentina
Merpem Argentina
Merrem Canada, Francia, Italia
Optinem Austria
Bibliografia   Iniezione   Bibliografia : Meropenem  
tipo pubblicazione
10 Rivista Patel PR, Cook SE.
Stability of meropenem in intravenous solutions.
Am J Health-Syst Pharm 1997 ; 54: 412-421.
266 Rivista Patel PR.
Compatibility of meropenem with commonly used injectable drugs.
Am J Health-Syst Pharm 1996 ; 53: 2853-2855.
1275 Rivista Walker SE, Varrin S, Yannicelli D, Law S.
Stability of meropenem in saline and dextrose solutions and compatibility with potassium chloride.
Can J Hosp Pharm 1998 ; 51: 156-168.
1415 Rivista Trissel L.A, Gilbert D.L, Martinez J.F, Baker M.B, Walter W.V, Mirtallo J.M.
Compatibility of medications with 3-in-1 parenteral nutrition admixtures.
JPEN 1999 ; 23: 67-74.
1454 Rivista Grant EM, Zhong MK, Ambrose PG, Nicolau DP, Nightingale CH, Quiniliani R.
Stability of meropenem in a portable infusion device in a cold pouch.
Am J Health-Syst Pharm 2000 ; 57: 992-995.
1508 Rivista Voirol P, Berger-Gryllaki M, Pannatier A, Eggimann P, Sadeghipour F.
Visual compatibility of insulin aspart with intravenous drugs frequently used in ICU.
EJHP 2015 ;22:123-124.
1639 Rivista Krämer I.
Stability of meropenem in elastomeric portable infusion devices.
Eur Hosp Pharm 1997 ; 3: 168-171.
1754 Rivista Trissel LA, Gilbert DL, Wolkin AC.
Compatibility of docetaxel with selected drugs during simulated Y-site administration.
Int J Pharm Compound 1999 ; 3: 241-244.
1925 Rivista Trissel LA , Williams KY, Gilbert DL.
Compatibility screening of linezolid injection during simulated Y-site administration with other drugs and infusion solutions.
J Am Pharm Assoc 2000 ; 40: 515-519.
1942 Rivista Smith DL, Bauer SM, Nicolau DP.
Stability of meropenem in polyvinyl chloride bags and an elastomeric infusion device.
Am J Health-Syst Pharm 2004 ; 61: 1682-1685.
1982 Rivista Trissel LA, Ogundele AB.
Compatibility of anidulafungin with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2005 ; 62: 834-837.
2017 Rivista Barker B, Feddema S, Rusho WJ, Dengg R.
Visual compatibility of vasopressin with other injectable drugs.
Am J Health-Syst Pharm 2005 ; 62: 1969-1976.
2042 Rivista Viaene E, Chanteux H, Servais H, Mingeot-Leclerq MP, Tulkens PM.
Comparative stability studies of antipseudomonal ß-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor-operated syringes (intensive care units).
Antimicrob Agents Chemother 2002 ; 46: 2327-2332.
2090 Rivista Pere H, Chasse V, Forest JM, Hildgen P.
Compatibility of injectable pantoprazole in Y-site administration.
Pharmactuel 2004 ; 37: 193-196.
2109 Rivista Pelletier E, Forest JM, Hildgen P.
Compatibilité de la kétamine injectable lors de l’administration en dérivé avec d’autres médicaments usuels.
Pharmactuel 2006 ; 39: 71-75.
2120 Rivista Mendez A.S.L, Dalomo J, Steppe M; Schapoval E.E.S.
Stability and degradation kinetics of meropenem in powder for injection and reconstituted sample.
J Pharm Biomed Anal 2006 ; 41: 1363-1366.
2231 Rivista de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S.
Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.
J Antimicrob Chemother 2008 ; 61, 2: 382-388.
2233 Rivista Condie C.K, Tyler L.S, Barker B, Canann D.M.
Visual compatibility of caspofungin acetate with commonly used drugs during simulated Y-site delivery
Am J Health-Syst Pharm 2008 ; 65, 5: 454-457.
2247 Rivista Chan P, Heatherly K, Kupiec T.C, Trissel L.A.
Compatibility of caspofungin acetate injection with other drugs during simulated Y-site coadministration.
Int J Pharm Compound 2008 ; 12, 3: 276-278.
2335 Rivista Canann D, Tyler L.S, Barker B, Condie C.
Visual compatibility of i.v. medications routinely used in bone marrow transplant recipients
Am J Health-Syst Pharm 2009 ; 66, 8: 727-729
2793 Rivista Tomasello C, Leggieri A, Cavalli R, Di Perri G, D?Avolio A.
In Vitro Stability Evaluation of Different Pharmaceutical Products Containing Meropenem.
Hosp Pharm 2015 ; 50, 4 : 296-303.
3012 Rivista Sullivan T, Forrest J.M, Leclair G.
Compatibility of Cloxacillin Sodium with Selected Intravenous Drugs During Simulated Y-Site Administration
Hosp Pharm 2015 ; 50, 3: 214-220.
3112 Rivista Berthoin K, Le Duff, CS , Marchand-Brynaert J, Carryn S, Tulkens PM
Stability of meropenem and doripenem solutions for administration by continuous infusion
J Antimicrob Chemother 2010 ; 65: 1073-1075
3152 Rivista Kumar A, Mann HJ.
Visual compatibility of oritavancin diphosphate with selected coadministered drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2010 ; 67: 1640-1644.
3216 Rivista Legris ME, Valiquette ME, Lavoie A, Forest JM, Leclair G.
Compatibilité physique par évaluation visuelle du salbutamol injectable lors de son administration en Y.
Pharmactuel 2011 ; 44, 1 : 14-18
3254 Rivista Housman S.T, Tessier P.R, Nicolau D.P, Kuti J.L.
Physical compatibility of telavancin hydrochloride with select i.v. drugs during simulated Y-site administration
Am J Health-Syst Pharm 2011 ; 68: 2265-2270.
3408 Rivista Tollec S, Touzin K, Pelletier E, Forest J.M.
Evaluation visuelle de la compatibilité physique de la naloxone avec d’autres médicaments intraveineux usuels.
Pharmactuel 2013 ; 46, 1 : 16-21.
3475 Rivista Chen L.Y, Chen J, Waters V, Boodhan S.
Incompatibility of ciprofloxacin and meropenem injections.
Am J Health-Syst Pharm 2013 ;70:1966-1970.
3549 Laboratorio Amikacine B Braun - Résumé des caractéristiques du produit.
B Braun 2012
3595 Laboratorio Aciclovir - Summary of Product Characteristics
Hospira 2009
3674 Laboratorio Erythromycin lactobionate - Summary of Product Characteristics
PanPharma 2016
3767 Rivista Legris M.E, Lavoie A, Forrest J.M, Hildgen P.
Compatibilité par évaluation visuelle du thiopental injectable lors de son administration en Y avec des médicaments usuels.
Pharmactuel 2014 ; 47, 3 : 167-172.
3824 Rivista Boudi S, Roy H, Forest JM, Leclair G.
Compatibilité physique de l'association amoxicilline-acide clavulanique en injection avec plusieurs autres médicaments lors d'une administration en Y.
Pharmactuel 2023 2023;56,3:91-98
3827 poster Ghazi I.M, Hamada Y, Nicolau D.P.
Compatibility of tedizolid phosphate with selected intravenous drugs via simulated Y-site conditions.
ASHP Midyear 2015
3828 poster Thabit A.K, Hamada Y, Nicolau D.P.
Ceftozolane/tazobactam physical compatibility during simulated Y-site administration.
ASHP Midyear 2015
3829 poster So W, Kim L, Thabit A.K, Nicolau D.P, Kuti J.L.
Compatibility of isavunazonium sulfate during simulated Y-site administration.
ASHP Midyear 2015
3837 Rivista Jaruratanasirikul S, Sriwiriyajan S.
Stability of meropenem in normal saline solution after storage at room temperature.
South Asian J Trop Med Pub Health 2003 ; 34: 627-629.
3879 Rivista Foushee Jaime A, Meredith Pmichaele, Fox Laura M, Grace Edward E.
Y-site Physical Compatibility of Beta-blocker Infusions with Intensive Care Unit Admixtures.
Int J Pharm Compound 2016 ; 20, 4 : 328-332.
3922 Rivista Wiesholzer, Winter A, Kussmann M, Zeitlinger M, Pichler P, Burgmann H, Reznicek G,Poepp l W.
Compatibility of meropenem with different commercial dialysis solutions.
Perit Dial Int 2016 doi:10.3747/pdi.2016.0001
3948 Rivista Bouchoud L, Fonzo-Christe C, Klingm?ller M, Bonnabry P .
Compatibility of Intravenous Medications With Parenteral Nutrition - In Vitro Evaluation.
JPEN 2012 ;30. 416?424.
3964 Rivista Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G.
Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments.
Pharmactuel 2017 ; 50,1 : 27-33.
3976 Rivista Du Repaire T, Vigne P, Guedon A, Gauthier-Villano L, Bertault Peres P, Pourroy B.
Visual compatibility of blinatumomab with selected co-administrated drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2017 ; 74,16 : 1217-1218
3997 Rivista Katip W.
Visual compatibility of colistin injection with other antibiotics during simulated Y-site administration.
Am J Health-Syst Pharm 2017 ; 74:14 : 1099-1102
4055 Rivista Monogue M, Almarzoky Abuhussain S, Kuti J, Nicolau D.
Physical compatibility of fosfomycin for injection with select i.v. drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2018 , 75, 1:36-44
4122 Rivista Fawaz S, Barton S, Whitney L, Swinden J, Nabhani-Gebara S.
Stability of Meropenem After Reconstitution for Administration by Prolonged Infusion.
Hosp Pharm 2018 ;54,3:190?196
4145 Rivista Asempa T.E, Avery L.M, Kidd J.M, Kuti J.L, Nicolau D.P.
Physical compatibility of plazomicin with select i.v. drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2018 ;75,14:1048-1056
4147 Rivista Carlier M, Stove V, Verstraete A.G, De Waele J.J.
Stability of generic brands of meropenem reconstituted in isotonic saline.
Minerva Anestesiologica 2014 ;81,3:283-287
4180 Rivista Mendes K, Harmanjeet H, Sedeeq M, Modi A, Wanandy T, Zaidi S, Ming L, Castelino R, Sud K, Peterson G, Patel R.
Stability of meropenem and piperacillin/tazobactam with heparin in various peritoneal dialysis solutions.
Perit Dial Int 2018 ;38,6:430-440
4290 Rivista Venugopalan V, Manigaba K, Borgert S.J, Cope J, Peloquin C.A, Klinker K.P.
Training a Drug to Do New Tricks: Insights on Stability of Meropenem Administered as a Continuous Infusion.
Microbiology Insights 2018 ; 11, 1-6
4319 Rivista Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G.
Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs.
Hosp Pharm 2020 ; 55, 5: 332-337.
4326 Rivista Curti C, Harti Souab K, Lamy E, Mathias F, Bornet C, Guinard B, Fersing C, Primas N, Albanèse J, Vanelle P.
Stability studies of antipyocyanic beta-lactam antibiotics used in continuous infusion.
Pharmazie 2019 ; 74: 357-362.
4380 Laboratorio Posaconazole (Noxafil®) - Summary of Product Characteristics
Merck Sharp & Dohme Limited 2019
4389 Rivista Côté K, Correal F, Metras M.E, Friciu M, Forest J.M, Leclair G.
Compatibilité physique des médicaments administrés en Y aux soins intensifs, en particulier la dexmédétomidine, le lévosimendan et la kétamine.
Pharmactuel 2019 ;52,4:206-213
4403 Rivista De Souza Barbosa F, Capra Pezzi L, Tsao M, Manoela Dias Macedo S, Franco de Oliveira T, Schapoval EES, Mendez ASL.
Stability in clinical use and stress testing of meropenem antibiotic by direct infusion ESI-Q-TOF: Quantitative method and identification of degradation products.
J Pharm Biomed Anal 2020 ; 179: 112973.
4405 Rivista Ezquer-Garin C, Ferriols-Lisart R, Martinez-López LM, Sangrador-Pelluz C, Nicolás-Picó J, Alós-Almiñana M.
Stability of tedizolid phosphate-sodium rifampicin and tedizolid phosphate-meropenem admixtures in intravenous infusion bags stored at different temperatures
Pharmazie 2020 ; 75: 172-176.
4434 Rivista Avery L.M, Chen, I.H, Reyes, S, Nicolau, D.P, Kuti J.L.
Assessment of the Physical Compatibility of Eravacycline and Common Parenteral Drugs During Simulated Y-site Administration.
Clin Ther 2019 ; 41, 10: 2162-2170.
4440 Rivista Omotani S, Aoe M, Esaki S, Nagai K, Hatsuda Y, Mukai J, Teramachi H, Myotoku M.
Compatibility of Intravenous Fat Emulsion with Antibiotics for Secondary Piggyback Infusion.
Ann Nutr Metab 2018 ; 73: 227-233.
4465 Rivista Foushee A, Meredith P, Fox Laura, Wilder A.
Y-site physical compatibility of hydrocortisone continuous infusions with admixtures used in critically ill patients.
Am J Health-Syst Pharm 2020 ;77,14:1144-1148
4470 Rivista Claeysoone K, Basma V, Hens R, Van Bambeke F, de Jongh R, Tulkens P.
Continuous versus intermittent infusion of temocillin in intensive care unit patient.
Critical care 2005 ; 9(Suppl 1) P37
4528 Rivista Lu J, Liu Q, Kupiec T, Vail H, Lunch L, Fam D, Vu N.
Physical Compatibility of Cefiderocol with Selected Intravenous Drugs During Simulated Y-site Administration.
Int J Pharm Compound 2021 ;25,1:52-61
4543 Rivista Senarathna G, Strunk T, Petrovski M, Batty K.
Physical compatibility of pentoxifylline and intravenous medications.
Archives of Disease in Childhood 2018 ;104:292–295.
4572 Rivista Gostynska A, Piwowarczyk L, Nadolna M, Jelinska A, Dettlaff K, Ogrodowczyk M, Popielarz-Brzezinska M, Stawny M.
Toward Safe Pharmacotherapy: The Interplay between Meropenem and Parenteral Nutrition Admixtures.
Antibiotics 2021 ; 10, 217.
4592 Rivista Liebchen U, Rakete S, Vogeser M, Arend F.M, Kinast C, Scharf C, Zoller M, Schönermarck U, Paal M.
The Role of Non-Enzymatic Degradation of Meropenem—Insights from the Bottle to the Body.
Antibiotics 2021 ; 10: 715.
4603 Rivista Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G.
Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration.
Hosp Pharm 2021 ; 56, 4: 228-234.
4634 Rivista Loeuille G, D'Huart E, Vigneron J, Nisse YE, Beiler B, Polo C, Ayari G, Sacrez M, Demoré B, Charmillon A.
Stability studies of 16 Antibiotics for Continuous Infusion in Intensive Care Units and for Performing Outpatient Parenteral Antimicrobial Therapy.
Antibiotics 2022 ;11,4: 458
4654 poster Sicard G, Donnette M, Martin N, Gensollen S, Pourroy B, Fanciullino R.
Compatibilité visuelle du Vyxeos® lors d'administration en Y avec une sélection de médicaments injectables.
Communication personnelle 2021
4742 Rivista Macoviciuc M, Nguyen C, Forest J-M, Leclair G.
Compatibilité physique de l’acétaminophène injectable avec 102 autres médicaments lors d’une administration en Y.
Pharmactuel 2022 ; 55, 4: 247-255.
4801 Rivista Ruiz V, Yuwei Shen Y, Abouelhassan Y, Fouad A, Nicolau D, Kuti J.
Physical compatibility of sulbactam/durlobactam with select intravenous drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2024 ;51,1:
4837 Rivista De Silva, D.T.N Petrovski M, Strunk T, Mukadam N, Page‑Sharp N, Moore B.R, Batty K.T.
Physicochemical compatibility of caffeine citrate and caffeine base injections with parenteral medications used in neonatal intensive care settings.
Eur J Clin Pharmacol 2024 ; 80:1079–1087.

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