Last update :
19/11/2024
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Anxiolytic   Lorazepam  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Ativan Great Britain, United States of America
Tavor Italy
Temesta Austria, Belgium, France, Netherlands, Switzerland
Stability in solutions   injection   Stability in solutions : Lorazepam     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
350

Glass Sodium chloride 0,9% 0,167 mg/ml 2-8°C Not specified
1 Day
4248
Level of evidence B+
Glass Sodium chloride 0,9% 0,167 mg/ml 20-25°C Not specified
1 Day
4248
Level of evidence B+
Glass Glucose 5% 1 & 2 mg/ml 22°C Light
28 Hour
765
Level of evidence A
Glass None 2 mg/ml 4°C-10°C Protect from light
210 Day
1424

Polyvinyl chloride Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
350

Polyvinyl chloride Glucose 5% 1 mg/ml 25°C Not specified
24 Hour
935
Level of evidence D
Polyethylene Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
350

Polyolefine NaCl 0,9% or Glucose 5% 0,1 mg/ml -20°C Protect from light
7 Day
175
Level of evidence B
Polyolefine NaCl 0,9% or Glucose 5% 0,1 mg/ml 24°C Protect from light
7 Day
175
Level of evidence B
Polyolefine NaCl 0,9% or Glucose 5% 0,1 mg/ml 37°C Protect from light
3 Day
175
Level of evidence B
Polyolefine NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
7 Day
175
Level of evidence B
Polyolefine Sodium chloride 0,9% 0,91 mg/ml -20°C Protect from light
35 Day
1935
Level of evidence A
Polyolefine Sodium chloride 0,9% 0,91 mg/ml 24°C Not specified
35 Day
1935
Level of evidence A
Polyolefine Sodium chloride 0,9% 0,91 mg/ml 37°C Not specified
5 Day
1935
Level of evidence A
Polyolefine Sodium chloride 0,9% 0,91 mg/ml 4°C Not specified
35 Day
1935
Level of evidence A
Polyolefine Glucose 5% 0,2 mg/ml 25°C Light
24 Hour
2146
Level of evidence B
Polyolefine Ringer’s lactate solution 0,1 mg/ml -20°C Protect from light
7 Day
175
Level of evidence B
Polyolefine Ringer’s lactate solution 0,1 mg/ml 24°C Protect from light
7 Day
175
Level of evidence B
Polyolefine Ringer’s lactate solution 0,1 mg/ml 37°C Protect from light
3 Day
175
Level of evidence B
Polyolefine Ringer’s lactate solution 0,1 mg/ml 4°C Protect from light
7 Day
175
Level of evidence B
Polypropylen Syringe NaCl 0,9% or Glucose 5% 1 mg/ml 22°C Light
28 Hour
765
Level of evidence A
Polypropylen Syringe Sodium chloride 0,9% 0,167 mg/ml 2-8°C Not specified
2 Day
4248
Level of evidence B+
Polypropylen Syringe Sodium chloride 0,9% 0,167 mg/ml 20-25°C Not specified
4 Day
4248
Level of evidence B+
  Mentions Légales