Last update :
18/07/2024
References   References 2146  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/63/23/2379

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Xu QA, Baker M.
Title : Drug compatibility with new polyolefin infusion solution containers.
Reference : Am J Health-Syst Pharm ; 63: 2379-2382. 2006

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Search of DEHP 
Comments : 
No comments for the degradation products

List of drugs
injectionAmiodarone hydrochloride Anti-arrhythmic
Stability in solutions Polyolefine Glucose 5% 0,9 mg/ml 25°C Light
24 Hour
injectionCarmustine Anticancer drug
Stability in solutions Polyolefine Glucose 5% 1 mg/ml 23°C Light
6 Hour
injectionLorazepam Anxiolytic
Stability in solutions Polyolefine Glucose 5% 0,2 mg/ml 25°C Light
24 Hour
injectionNitroglycerin Vasodilator
Stability in solutions Polyolefine Glucose 5% 0,42 mg/ml 25°C Light
24 Hour
injectionSufentanil citrate Analgesic
Stability in solutions Polyolefine Glucose 5% 0.005 mg/ml 25°C Light
24 Hour
injectionThiopental sodium General anesthetic
Stability in solutions Polyolefine Glucose 5% 9 mg/ml 25°C Light
24 Hour

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