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Analgesic   Morphine hydrochloride  
injection
Ointments
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Amidiaz Argentina
Analfin Mexico
Morfin Norway, Sweden
Morfina clorhidrato Chile, Ecuador, Italy, Peru
Morfine Netherlands
Morphin Finland
Morphine Belgium, France
Stellorphine Belgium
Vendal Austria
Stability of mixtures   injection   Stability of mixtures : Morphine hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,2 mg/ml
injection   Morphine hydrochloride   
injection   Bupivacaine hydrochloride 7,5 mg/ml
20°C-25°C
540 Day
Light 1885
Level of evidence A
Glass Sodium chloride 0,9% 0,25 mg/ml
injection   Morphine hydrochloride   
injection   Hydromorphone hydrochloride 0,05 mg/ml
25°C
15 Day
Not specified 4667
Level of evidence D
Glass Sodium chloride 0,9% 0,25 mg/ml
injection   Morphine hydrochloride   
injection   Hydromorphone hydrochloride 0,05 mg/ml
37°C
15 Day
Not specified 4667
Level of evidence D
Polyvinyl chloride Not specified 6,66 mg/ml
injection   Morphine hydrochloride   
injection   Bupivacaine hydrochloride 3 mg/ml
injection   Clonidine hydrochloride 0,03 mg/ml
25°C
90 Day
Not specified 346
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 25 mg/ml
injection   Morphine hydrochloride   
injection   Esketamine 20 mg/ml
injection   Metamizol sodium 50 mg/ml
22°C
7 Day
Not specified 4664
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 25 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 50 mg/ml
22°C
7 Day
Not specified 4664
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,25 mg/ml
injection   Morphine hydrochloride   
injection   Hydromorphone hydrochloride 0,05 mg/ml
25°C
15 Day
Not specified 4667
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0.2 >> 18 mg/ml
injection   Morphine hydrochloride   
injection   Haloperidol lactate 0.02 >> 0.2 mg/ml
37°C
7 Day
Not specified 2362
Polyvinyl chloride Sodium chloride 0,9% 0,25 mg/ml
injection   Morphine hydrochloride   
injection   Hydromorphone hydrochloride 0,05 mg/ml
37°C
15 Day
Not specified 4667
Level of evidence D
Polyethylene Sodium chloride 0,9% 0,25 mg/ml
injection   Morphine hydrochloride   
injection   Hydromorphone hydrochloride 0,05 mg/ml
25°C
15 Day
Not specified 4667
Level of evidence D
Polyethylene Sodium chloride 0,9% 0,25 mg/ml
injection   Morphine hydrochloride   
injection   Hydromorphone hydrochloride 0,05 mg/ml
37°C
15 Day
Not specified 4667
Level of evidence D
Polypropylene Sodium chloride 0,9% 1 mg/ml
injection   Morphine hydrochloride   
injection   Baclofen 0.08 mg/ml
2-8°C
7 Day
Protect from light 4051
Level of evidence A
Polypropylene Sodium chloride 0,9% 10 mg/ml
injection   Morphine hydrochloride   
injection   Baclofen 1.6 mg/ml
2-8°C
7 Day
Protect from light 4051
Level of evidence A
Polypropylene Sodium chloride 0,9% 10 mg/ml
injection   Morphine hydrochloride   
injection   Baclofen 1.6 mg/ml
23-27°C
7 Day
Protect from light 4051
Level of evidence A
Polypropylene Sodium chloride 0,9% 1 mg/ml
injection   Morphine hydrochloride   
injection   Baclofen 0.08 mg/ml
23-27°C
7 Day
Protect from light 4051
Level of evidence A
Polypropylene Sodium chloride 0,9% 1,67>> 10 mg/ml
injection   Morphine hydrochloride   
injection   Scopolamine N-butyl bromide 5 & 6,67 mg/ml
injection   Haloperidol lactate 0,42 & 0,62 mg/ml
25°C
15 Day
Protect from light 2055
Level of evidence B+
Polypropylene Sodium chloride 0,9% 1,67>> 10 mg/ml
injection   Morphine hydrochloride   
injection   Scopolamine N-butyl bromide 3,33>>6,67 mg/ml
25°C
15 Day
Protect from light 1966
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,67>> 10 mg/ml
injection   Morphine hydrochloride   
injection   Scopolamine N-butyl bromide 3,33>>6,67 mg/ml
4°C
15 Day
Protect from light 1966
Level of evidence C+
Ethylene vinyl acetate Sodium chloride 0,9% 0.2 >> 18 mg/ml
injection   Morphine hydrochloride   
injection   Haloperidol lactate 0.02 >> 0.2 mg/ml
2-8°C
14 Day
Protect from light 2362
Ethylene vinyl acetate Sodium chloride 0,9% 0.2 >> 18 mg/ml
injection   Morphine hydrochloride   
injection   Haloperidol lactate 0.02 >> 0.2 mg/ml
37°C
7 Day
Not specified 2362
Ethylene vinyl acetate None 2,5 >> 5 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 250 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 2,5 >> 5 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 200 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 10 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 100 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 10 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 200 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 10 >> 20 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 66,67 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 35 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 43 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 35 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 58 mg/ml
2-8°C
21 Day
Not specified 2363
Ethylene vinyl acetate None 2,5 >> 5 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 200  mg/ml
37°C
3 Day
Not specified 2363
Ethylene vinyl acetate None 2,5 >> 5 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 250 mg/ml
37°C
3 Day
Not specified 2363
Ethylene vinyl acetate None 10 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 200 mg/ml
37°C
3 Day
Not specified 2363
Ethylene vinyl acetate None 10 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 100 mg/ml
37°C
3 Day
Not specified 2363
Ethylene vinyl acetate None 10 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 100 mg/ml
37°C
3 Day
Not specified 2363
Ethylene vinyl acetate None 10 >> 20 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 66,67 mg/ml
37°C
4 Day
Not specified 2363
Ethylene vinyl acetate None 35 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 58 mg/ml
37°C
7 Day
Not specified 2363
Ethylene vinyl acetate None 35 mg/ml
injection   Morphine hydrochloride   
injection   Metamizol sodium 43 mg/ml
37°C
7 Day
Not specified 2363
Polypropylen Syringe Sodium chloride 0,9% 0,417 mg/ml
injection   Morphine hydrochloride 4,3  
injection   Clonidine hydrochloride 0,003 mg/ml
2-8°C
30 Day
Not specified 4643
Level of evidence A+
Polypropylen Syringe Sodium chloride 0,9% 4,3 mg/ml
injection   Morphine hydrochloride 4,3  
injection   Clonidine hydrochloride 0,032 mg/ml
2-8°C
30 Day
Not specified 4643
Level of evidence A+
  Mentions Légales