Last update :
27/11/2024
Analgesic   Morphine hydrochloride  
injection
Ointments
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Amidiaz Argentina
Analfin Mexico
Morfin Norway, Sweden
Morfina clorhidrato Chile, Ecuador, Italy, Peru
Morfine Netherlands
Morphin Finland
Morphine Belgium, France
Stellorphine Belgium
Vendal Austria
Compatibility   injection   Compatibility : Morphine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Morphine hydrochloride 2 mg/ml
injection Alprostadil 20 µg/ml
Glucose 5% 4651
Immediate precipitation Incompatible
injection Morphine hydrochloride 0,2 mg/ml
injection Ampicillin sodium 100 mg/ml
Sodium chloride 0,9% 4831
Compatible
injection Morphine hydrochloride 2.5 >> 15 mg/ml
injection Atropine sulfate 0.5 mg/ml
Water for Injection 1757
Immediate precipitation Incompatible
injection Morphine hydrochloride 1 mg/ml
injection Blinatumomab 0.125 & 0.375 µg/ml
Sodium chloride 0,9% 3976
Compatible
injection Morphine hydrochloride 0,2 mg/ml
injection Bupivacaine hydrochloride 7,5 mg/ml
Sodium chloride 0,9% 1885
Compatible
injection Morphine hydrochloride 0.2 mg/ml
injection Caffeine 10 mg/ml
Glucose 5% 4837
Compatible
injection Morphine hydrochloride 0,2 mg/ml
injection Caffeine citrate 20 mg/ml
Glucose 5% 4837
Compatible
injection Morphine hydrochloride 0,2 mg/ml
injection Cefotaxime sodium 40 mg/ml
4832
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Clonidine hydrochloride 0.0075 mg/ml
NaCl 0,9% or Glucose 5% 1506
Immediate precipitation Incompatible
injection Morphine hydrochloride 1 >> 50 mg/ml
injection Dexamethasone sodium phosphate 0.5 >> 20 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1.68 & 5 mg/ml
injection Dexamethasone sodium phosphate 0.44 & 1.33 mg/ml
Sodium chloride 0,9% 1971
Immediate precipitation Incompatible
injection Morphine hydrochloride
injection Diclofenac
Sodium chloride 0,9% 3470
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Dobutamine hydrochloride 8 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Dopamine hydrochloride 8 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Morphine hydrochloride 0,2 mg/ml
injection Dopamine hydrochloride 2 mg/ml
4832
Compatible
injection Morphine hydrochloride 15 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
injection Morphine hydrochloride
injection Eptifibatide
3934
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Esomeprazole sodium 0.32 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Morphine hydrochloride 0,2 mg/ml
injection Flecainide acetate 2 mg/ml
Sodium chloride 0,9% 4831
Compatible
injection Morphine hydrochloride 0,2 mg/ml
injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 4831
Unspecified incompatibility Incompatible
injection Morphine hydrochloride
injection Fluorouracil
3474
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Glycerophosphate disodium
Sodium chloride 0,9% 4332
Compatible
injection Morphine hydrochloride 0.2 >> 18 mg/ml
injection Haloperidol lactate 0.02 >> 0.2 mg/ml
Sodium chloride 0,9% 2362
Immediate precipitation Incompatible
injection Morphine hydrochloride 5 > 50 mg/ml
injection Haloperidol lactate 3 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1 >> 20 mg/ml
injection Haloperidol lactate 1 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1.68 & 5 mg/ml
injection Haloperidol lactate 0.21 & 0.62 mg/ml
Sodium chloride 0,9% 1971
Compatible
injection Morphine hydrochloride 1 >> 3 mg/ml
injection Haloperidol lactate 3 mg/ml
Sodium chloride 0,9% 1866
Immediate precipitation Incompatible
injection Morphine hydrochloride 15 > 50 mg/ml
injection Haloperidol lactate 2 mg/ml
Sodium chloride 0,9% 1866
Immediate precipitation Incompatible
injection Morphine hydrochloride 3 > 50 mg/ml
injection Haloperidol lactate 4 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1 >> 10 mg/ml
injection Haloperidol lactate 2 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Haloperidol lactate 5 mg/ml
Sodium chloride 0,9% 1866
Immediate precipitation Incompatible
injection Morphine hydrochloride 2 > 50 mg/ml
injection Haloperidol lactate 5 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1 & 2 mg/ml
injection Haloperidol lactate 4 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 0,2 mg/ml
Parenteral nutrition (with lipids) 4832
Compatible
injection Morphine hydrochloride 2.5 >> 15 mg/ml
injection Haloperidol lactate 2.5 mg/ml
Water for Injection 1757
Compatible
injection Morphine hydrochloride 2 >> 5 mg/ml
injection Haloperidol lactate 0.25 >> 0.5 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
injection Morphine hydrochloride 1.18 >> 3.53 mg/ml
injection Ketorolac tromethamine 1.76 & 3.53 mg/ml
Sodium chloride 0,9% 3470
Incompatible
injection Morphine hydrochloride 1,3 >> 3 mg/ml
injection Ketorolac tromethamine 3,4 >> 4 mg/ml
3169
Compatible
injection Morphine hydrochloride 4.7 mg/ml
injection Ketorolac tromethamine 1.76 mg/ml
Sodium chloride 0,9% 3470
Compatible
injection Morphine hydrochloride 2 >> 5 mg/ml
injection Levomepromazine 0.625 >> 2.5 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Lorazepam 0.33 mg/ml
Sodium chloride 0,9% 186
Compatible
injection Morphine hydrochloride 0.3 mg/ml
injection Lornoxicam 0.4 mg/ml
Sodium chloride 0,9% 4034
Compatible
injection Morphine hydrochloride <10 mg/ml
injection Methylprednisolone sodium succinate 0.1 >> 9 mg/ml
Sodium chloride 0,9% 1866
Immediate precipitation Incompatible
injection Morphine hydrochloride 10 >> 50 mg/ml
injection Methylprednisolone sodium succinate 0.1 >> 9 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 1.67 >> 10 mg/ml
injection Metoclopramide hydrochloride 3.33 mg/ml
Water for Injection 1757
Compatible
injection Morphine hydrochloride 1.68 & 5 mg/ml
injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Sodium chloride 0,9% 1971
Compatible
injection Morphine hydrochloride 2 >> 5 mg/ml
injection Metoclopramide hydrochloride 3 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Midazolam hydrochloride 5 mg/ml
None 186
Compatible
injection Morphine hydrochloride 10 >> 40 mg/ml
injection Midazolam hydrochloride 1 >> 3 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 0,2 mg/ml
Parenteral nutrition (binary mixture) 4832
Immediate precipitation Incompatible
injection Morphine hydrochloride > 30 mg/ml
injection Midazolam hydrochloride > 4 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 2 >> 5 mg/ml
injection Midazolam hydrochloride 1.2 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
injection Morphine hydrochloride 1.68 & 5 mg/ml
injection Midazolam hydrochloride 0.5 & 1.5 mg/ml
Sodium chloride 0,9% 1971
Immediate precipitation Incompatible
injection Morphine hydrochloride > 40 mg/ml
injection Midazolam hydrochloride 1 >> 3 mg/ml
Sodium chloride 0,9% 1866
Compatible
injection Morphine hydrochloride 2 mg/ml
injection Nafamostat 10 mg/mL
Glucose 5% 4545
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Norepinephrine bitartrate 0.32 mg/ml
NaCl 0,9% or Glucose 5% 1506
Unspecified incompatibility Incompatible
injection Morphine hydrochloride
injection Parecoxib sodium
3504
Immediate precipitation Incompatible
injection Morphine hydrochloride 0,2 mg/ml
injection Penicillin G sodium 0.17 MUI/ml
Sodium chloride 0,9% 4831
Compatible
injection Morphine hydrochloride 0,02 mg/ml
injection Pentoxifyllin 5 mg/ml
Sodium chloride 0,9% 4543
Compatible
injection Morphine hydrochloride 0,08 & 0,2 mg/ml
injection Pentoxifyllin 5 mg/ml
Glucose 5% 4538
Compatible
injection Morphine hydrochloride 10 mg/ml
injection Phloroglucinol 2,5 mg/ml
3791
Compatible
injection Morphine hydrochloride 15 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Morphine hydrochloride 15 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Compatible
injection Morphine hydrochloride 1 mg/ml
injection Quinupristine/dalfopristine 2 mg/ml
Glucose 5% 1513
Compatible
injection Morphine hydrochloride 1.67 >> 10 mg/ml
injection Ranitidine hydrochloride 16.67 mg/ml
Water for Injection 1757
Compatible
injection Morphine hydrochloride 10 mg/ml
injection Remdesivir 1 mg/ml
Sodium chloride 0,9% 4768
Compatible
injection Morphine hydrochloride 1.67 >> 10 mg/ml
injection Scopolamine N-butyl bromide 3.33 >> 6.67 mg/ml
Sodium chloride 0,9% 1966
Compatible
injection Morphine hydrochloride 2 >> 5 mg/ml
injection Scopolamine N-butyl bromide 3-7 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
injection Morphine hydrochloride 2.5 >> 15 mg/ml
injection Scopolamine N-butyl bromide 10 mg/ml
Water for Injection 1757
Compatible
injection Morphine hydrochloride 1.68 & 5 mg/ml
injection Scopolamine N-butyl bromide 1.68 & 5 mg/ml
Sodium chloride 0,9% 1971
Unspecified incompatibility Incompatible
injection Morphine hydrochloride
injection Thiopental sodium
3675
Compatible
injection Morphine hydrochloride
injection Tigecycline
Sodium chloride 0,9% 3332

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