Monographie - Tramadol hydrochloride

Last update :
08/05/2024

Tramadol hydrochloride

Chemical structure

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acugesic	Malaysia
Adolonta	Spain
Amadol	Egypt
Analgon	Peru
Anangor	Brazil
Autrestol	Mexico
Contramal	Belgium, France, Hungary, Italy, Turkey
Dalarest	Mexico
Dolotramine	Switzerland
Dolzam	Belgium
Eufindol	Chile
Fortradol	Italy
Fraxidol	Italy
Lafedol	Argentina
Liochta	Mexico
Lumidol	Croatia
Mabron	Thailand
Megadol	Chile, Mexico
Nobligan	Denmark, Mexico, Sweden
Paxilfar	Portugal
Poltram	Poland
Prontalgin	Italy
Sylador	Brazil
Tadol	Slovenia
Topalgic	France
Trabilin	Saudi Arabia
Tradolan	Austria, Denmark, Sweden
Tradonal	Belgium, Thailand
Tramabene	Austria
Tramadoc	Germany
Tramadolor	Austria
Tramadura	Germany
Tramagetic	Netherlands
Tramal	Austria, Brazil, Croatia, Finland, Germany, Netherlands, Poland, Portugal, Republic of South Africa, Slovenia, Switzerland, Thailand
Tramastad	Austria
Tramundin	Germany
Zamadol	Great Britain
Zamudol	France
Zydol	Great Britain

References : Tramadol hydrochloride

	Type	Publication
365	Journal	Junfeng Gu, Wengang Qin, Fuchao Chen, Zhongyuan Xia. Long-Term Stability of Tramadol and Ketamine Solutions for Patient-Controlled Analgesia Delivery. Med Sci Monit 2015 ; 21:2528-2534.
1690	Journal	Müller H-J, Berg J. Stabilitätsstudie zu tramadolhydrochlorid im PVC-infusionbeutel. Krankenhauspharmazie 1997 ; 18: 75-79.
1892	Journal	Lebrun J, Hecq JD, Vanbeckbergen D, Jalart J, Galanti LM. Effect of freezing, long-term storage and microwave thawing on the stability of tramadol in 5% dextrose infusion in polyvinyl chloride bags. Int J Pharm Compound 2004 ; 8, 2: 156-159.
1971	Journal	Azuara ML, Sanchez Y, Reyes R, Barcia E. Physical compatibility and in vivo evaluation of drug mixtures forsubcutaneous infusion to cancer patients in palliative care. Support Care Cancer 2001
2002	Journal	Abanmy NO, Zaghloul IY, Radwan MA. Compatibility of tramadol hydrochloride injection with selected drugs and solutions. Am J Health-Syst Pharm 2005 ; 62: 1299-1302.
2024	Journal	Negro S, Martin A, Azuara ML, Sanchez Y, Barcia E. Stability of tramadol and haloperidol for continuous infusion at home. J Pain Symptom Manage 2005 ; 30: 192-199.
2139	Journal	Serrurier C, Chenot ED, Vigneron J, May I, Demor? B. Assessment of injectable drug’s administration in two intensive care units and determination of potential physico-chemical incompatibilities. EJHP Science 2006 ; 12,5: 96-99.
2176	Journal	Barcia E, Martin A, Azuara ML, Sanchez Y, Negro S. Tramadol and hyoscine N-butyl bromide combined in infusion solutions: compatibility and stability. Support Care Cancer 2007 ; 15: 57-62.
2211	Journal	Negro S, Salama A, S?nchez Y, AzuaraM.L, Barcia B. Compatibility and stability of tramadol and dexamethasone in solution and its use in terminally ill patients. J Clin Pharm Ther 2007 ; 32: 441-444.
2231	Journal	de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S. Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection. J Antimicrob Chemother 2008 ; 61, 2: 382-388.
2814	Journal	Lebitasy M, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L. Long-term stability of tramadol hydrochloride and droperidol mixture in 5% dextrose infusion polyolefin bags at 5 +/- 3°C. Ann Pharm Fr 2009 ; 67: 272-277.
3075	Journal	Balayssac D, Badaroux L, Rodier C, Sautou-Miranda V, Bazin JE, Chopineau J. Compatibility and stability of parenteral analgesic admixtures for multimodal analgesia EJHP Science 2009 ; 15, 4: 78-82.
3082	Journal	Athanasopoulos A, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L. Long-term stability of tramadol chlorhydrate and metoclopramide hydrochloride in dextrose 5% polyolefin bag at 4°C. J Oncol Pharm Practice 2009 ; 15: 195-200.
3115	Journal	Athanasopoulos A, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L. Long term stability of the hydrochloride of tramadol and alizapride in dextrose 5% polyolefin bags at 5 +/- 3°C. Ann Pharm Fr 2010 ; 68: 157-162.
3132	Journal	Negro S, Martin A, Azuara L, Sanchez Y, Barcia E. Compatibility and stability of ternary admixtures of tramadol, haloperidol, and hyoscine. J Palliat Med 2010 ; 13, 3: 273-277.
3159	Journal	Lin, T.-F., Lin, F.-S., Chou, W.-H., Yeh, Y.-C., Lin, C.-P., Fan, S.-Z., Sun, W.-Z. Compatibility and stability of binary mixtures of ketorolac tromethamine and tramadol hydrochloride injection concentrate and diluted infusion solution. Acta Anaesthesiol Taiwan 2010 ; 48, 3 : 117-121.
3296	Journal	Salmeron-Garcia A, Navas N, Martin A, Roman E, Cabeza J, Capitan-Vallvey L.F Determination of Tramadol, Metamizole, Ropivacaine, and Bupivacaine in Analgesic Mixture Samples by HPLC with DAD Detection. J Chromatographic Sci 2009 ; 47: 1-7.
3297	Journal	Salmeron-Garcia A, Lopez-Lopez E, Roma E, Cabeza J, Navas N, Capitan-Vallvey L.F. Development of an LC–DAD Method for Analysis of Dexketoprofen, Tramadol, and Haloperidol. Study of the Stability of Mixtures Used for Patient-Controlled Analgesia. Chromatographia 2008 ; 68, 9-10: 767-772.
3372	Journal	Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S. Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine. Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3521	Manufacturer	Tramadol® - Summary of Product Characteristics. Beacon Pharmaceuticals 2012
4034	Journal	Chen F-C, Fang B-X, Li P, Zheng F, Shi X-Y. Compatibility and stability of lornoxicam with morphine, tramadol or fentanyl in infusion solutions. Afr J Pharm Pharmacol 2012 ;27,6:2055-2060
4116	Journal	Chen F, Zhu J, Li B, Yuan F, Wang K. Stability of tramadol with three 5-HT3 receptor antagonists in polyolefin bags for patient-controlled delivery systems. Drug Design Dev Ther 2016 ;10:1869-1875
4521	Journal	Polo C, D’Huart E, Lesperlette G, Vigneron J, Meyer F, Demoré B. Compatibility of injectable posaconazole with drugs commonly used in a hematology care unit. Pharmaceutical Technology in Hospital Pharmacy 2020
4698	Journal	Ayari G, D'Huart E, Vigneron J, Demoré B. Y-site compatibility of intravenous medications commonly used in intensive care units : laboratory tests on 75 mixtures involving nine main drugs. Pharmaceutical Technology in Hospital Pharmacy 2022

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