Son güncelleme :
13/05/2025
Analjezik   Tramadol hydrochloride  
Enjeksiyon
Oral solüsyon / oral çözelti
Çözeltilerin stabilitesi Karışımlardaki stabilitesi Stabiliteyi etkileyen faktörler Uyumluluk Uygulama yöntemi Kaynaklar pdf
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Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acugesic Malezya
Adolonta İspanya
Amadol Mısır
Analgon Peru
Contramal Belçika, Fransa, İtalya, Macaristan, Türkiye
Eufindol Şili
Fortradol İtalya
Lafedol Arjantin
Liochta Meksika
Mabron İspanya, Malezya, Romanya
Megadol Kolombiya, Şili
Nobligan Danimarka
Paxilfar Portekiz
Poltram Polonya
Prontalgin İtalya
Sylador Suudi Arabistan
Tadol Slovenya
Topalgic Fransa
Trabilin Malezya, Suudi Arabistan
Tradolan Avusturya, Danimarka, İsveç, İzlanda
Tradonal Belçika, Lüksemburg
Tramabene Avusturya
Tramadolor Almanya, Avusturya, Hırvatistan
Tramagetic Almanya, Hollanda
Tramal Almanya, Arjantin, Birleşik Arap Emirlikleri, Brezilya, Ekvador, Finlandiya, Hollanda, İran, İsviçre, Kolombiya, Lüksemburg, Mısır, Peru, Polonya, Portekiz, Slovenya, Suudi Arabistan, Tunus, Venezuela, yeni Zelanda
Tramastad Avusturya
Zamadol Büyük Britanya, Hindistan
Zydol Büyük Britanya
Kaynaklar   Enjeksiyon    Kaynaklar : Tramadol hydrochloride  
tip yayın
365 Dergi Junfeng Gu, Wengang Qin, Fuchao Chen, Zhongyuan Xia.
Long-Term Stability of Tramadol and Ketamine Solutions for Patient-Controlled Analgesia Delivery.
Med Sci Monit 2015 ; 21:2528-2534.
1690 Dergi Müller H-J, Berg J.
Stabilitätsstudie zu tramadolhydrochlorid im PVC-infusionbeutel.
Krankenhauspharmazie 1997 ; 18: 75-79.
1892 Dergi Lebrun J, Hecq JD, Vanbeckbergen D, Jalart J, Galanti LM.
Effect of freezing, long-term storage and microwave thawing on the stability of tramadol in 5% dextrose infusion in polyvinyl chloride bags.
Int J Pharm Compound 2004 ; 8, 2: 156-159.
1971 Dergi Azuara ML, Sanchez Y, Reyes R, Barcia E.
Physical compatibility and in vivo evaluation of drug mixtures forsubcutaneous infusion to cancer patients in palliative care.
Support Care Cancer 2001
2002 Dergi Abanmy NO, Zaghloul IY, Radwan MA.
Compatibility of tramadol hydrochloride injection with selected drugs and solutions.
Am J Health-Syst Pharm 2005 ; 62: 1299-1302.
2024 Dergi Negro S, Martin A, Azuara ML, Sanchez Y, Barcia E.
Stability of tramadol and haloperidol for continuous infusion at home.
J Pain Symptom Manage 2005 ; 30: 192-199.
2139 Dergi Serrurier C, Chenot ED, Vigneron J, May I, Demor? B.
Assessment of injectable drug’s administration in two intensive care units and determination of potential physico-chemical incompatibilities.
EJHP Science 2006 ; 12,5: 96-99.
2176 Dergi Barcia E, Martin A, Azuara ML, Sanchez Y, Negro S.
Tramadol and hyoscine N-butyl bromide combined in infusion solutions: compatibility and stability.
Support Care Cancer 2007 ; 15: 57-62.
2211 Dergi Negro S, Salama A, S?nchez Y, AzuaraM.L, Barcia B.
Compatibility and stability of tramadol and dexamethasone in solution and its use in terminally ill patients.
J Clin Pharm Ther 2007 ; 32: 441-444.
2231 Dergi de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S.
Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.
J Antimicrob Chemother 2008 ; 61, 2: 382-388.
2814 Dergi Lebitasy M, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L.
Long-term stability of tramadol hydrochloride and droperidol mixture in 5% dextrose infusion polyolefin bags at 5 +/- 3°C.
Ann Pharm Fr 2009 ; 67: 272-277.
3075 Dergi Balayssac D, Badaroux L, Rodier C, Sautou-Miranda V, Bazin JE, Chopineau J.
Compatibility and stability of parenteral analgesic admixtures for multimodal analgesia
EJHP Science 2009 ; 15, 4: 78-82.
3082 Dergi Athanasopoulos A, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L.
Long-term stability of tramadol chlorhydrate and metoclopramide hydrochloride in dextrose 5% polyolefin bag at 4°C.
J Oncol Pharm Practice 2009 ; 15: 195-200.
3115 Dergi Athanasopoulos A, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L.
Long term stability of the hydrochloride of tramadol and alizapride in dextrose 5% polyolefin bags at 5 +/- 3°C.
Ann Pharm Fr 2010 ; 68: 157-162.
3132 Dergi Negro S, Martin A, Azuara L, Sanchez Y, Barcia E.
Compatibility and stability of ternary admixtures of tramadol, haloperidol, and hyoscine.
J Palliat Med 2010 ; 13, 3: 273-277.
3159 Dergi Lin, T.-F., Lin, F.-S., Chou, W.-H., Yeh, Y.-C., Lin, C.-P., Fan, S.-Z., Sun, W.-Z.
Compatibility and stability of binary mixtures of ketorolac tromethamine and tramadol hydrochloride injection concentrate and diluted infusion solution.
Acta Anaesthesiol Taiwan 2010 ; 48, 3 : 117-121.
3296 Dergi Salmeron-Garcia A, Navas N, Martin A, Roman E, Cabeza J, Capitan-Vallvey L.F
Determination of Tramadol, Metamizole, Ropivacaine, and Bupivacaine in Analgesic Mixture Samples by HPLC with DAD Detection.
J Chromatographic Sci 2009 ; 47: 1-7.
3297 Dergi Salmeron-Garcia A, Lopez-Lopez E, Roma E, Cabeza J, Navas N, Capitan-Vallvey L.F.
Development of an LC–DAD Method for Analysis of Dexketoprofen, Tramadol, and Haloperidol. Study of the Stability of Mixtures Used for Patient-Controlled Analgesia.
Chromatographia 2008 ; 68, 9-10: 767-772.
3372 Dergi Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S.
Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine.
Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3521 Laboratuar Tramadol® - Summary of Product Characteristics.
Beacon Pharmaceuticals 2012
4034 Dergi Chen F-C, Fang B-X, Li P, Zheng F, Shi X-Y.
Compatibility and stability of lornoxicam with morphine, tramadol or fentanyl in infusion solutions.
Afr J Pharm Pharmacol 2012 ;27,6:2055-2060
4116 Dergi Chen F, Zhu J, Li B, Yuan F, Wang K.
Stability of tramadol with three 5-HT3 receptor antagonists in polyolefin bags for patient-controlled delivery systems.
Drug Design Dev Ther 2016 ;10:1869-1875
4521 Dergi Polo C, D’Huart E, Lesperlette G, Vigneron J, Meyer F, Demoré B.
Compatibility of injectable posaconazole with drugs commonly used in a hematology care unit.
Pharmaceutical Technology in Hospital Pharmacy 2020
4698 Dergi Ayari G, D'Huart E, Vigneron J, Demoré B.
Y-site compatibility of intravenous medications commonly used in intensive care units : laboratory tests on 75 mixtures involving nine main drugs.
Pharmaceutical Technology in Hospital Pharmacy 2022 ; 7(1): 20220002
4842 Dergi Souha H Y, Alka G, Yunmei S, Nicole E W, Sanjay G.
Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors
Drug Design Dev Ther 2024 ;18: 899–908.
4855 Dergi Dettlaff K, Kowalska A, Gostyńska A.
Physical compatibility of colistin with analgesics during simulated Y-site administration.
Am J Hosp Pharm 2024 ;81,13:365-371

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