Last update :
29/10/2024
Anti-arrhythmic   Procainamide hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Biocoryl Spain
Procanbid United States of America
Pronestyl Canada, United States of America
Compatibility   injection   Compatibility : Procainamide hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Amiodarone hydrochloride 1.8 mg/ml
NaCl 0,9% or Glucose 5% 242
Compatible
injection Procainamide hydrochloride 3 mg/ml
injection Amiodarone hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 1036
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Argatroban 1 mg/ml
Glucose 5% 3764
Compatible
injection Procainamide hydrochloride 10 mg/ml
injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
injection Procainamide hydrochloride 1 mg/ml
injection Bretylium tosilate 1 mg/ml
NaCl 0,9% or Glucose 5% 1193
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Procainamide hydrochloride 10 mg/ml
injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
injection Procainamide hydrochloride 10 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
injection Procainamide hydrochloride 2 mg/ml
injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Immediate turbidity Incompatible
injection Procainamide hydrochloride 500 mg/ml
injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
injection Procainamide hydrochloride 50 mg/ml
injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Compatible
injection Procainamide hydrochloride 1 mg/ml
injection Dobutamine hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1058
Compatible
injection Procainamide hydrochloride 8 & 100 mg/ml
injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 1041
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Esmolol hydrochloride 6 mg/ml
Glucose 5% 174
Compatible
injection Procainamide hydrochloride 5 mg/ml
injection Famotidine 0.2 mg/ml
Glucose 5% 398
Compatible
injection Procainamide hydrochloride 10 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Flumazenil 0,02 mg/ml
Glucose 5% 187
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Heparin sodium 1 UI/ml
Ringer’s lactate solution 1228
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Heparin sodium 1 UI/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Procainamide hydrochloride 10 mg/ml
injection Hetastarch 60 mg/ml
specific solvent 1721
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Ringer’s lactate solution 1228
Immediate precipitation Incompatible
injection Procainamide hydrochloride 20 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Procainamide hydrochloride 1 mg/ml
injection Lidocaine hydrochloride 2 mg/ml
Ringer’s lactate solution 619
Compatible
injection Procainamide hydrochloride 1 mg/ml
injection Lidocaine hydrochloride 2 mg/ml
NaCl 0,9% or Glucose 5% 619
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Procainamide hydrochloride 8 mg/ml
injection Metoprolol tartrate 1 mg/ml
Sodium chloride 0,9% 2346
Chemical instability Incompatible
injection Procainamide hydrochloride 1 >> 4 mg/ml
injection Milrinone lactate 0.175 & 0.200 mg/ml
Glucose 5% 191
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Netilmicin sulfate 3 mg/ml
NaCl 0,9% or Glucose 5% 1200
Compatible
injection Procainamide hydrochloride
injection Pantoprazole sodium
2090
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Ranitidine hydrochloride 0,5 mg/ml
Glucose 5% 396
Incompatible
injection Procainamide hydrochloride
Glucose 5% 1115
Chemical instability Incompatible
injection Procainamide hydrochloride
Glucose 5% 1461
Incompatible
injection Procainamide hydrochloride
Glucose 5% 705
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Compatible
injection Procainamide hydrochloride 100 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Procainamide hydrochloride 4 mg/ml
injection Vasopressin 2 & 4 UI/ml
Sodium chloride 0,9% 1801
Compatible
injection Procainamide hydrochloride 2 mg/ml
injection Verapamil hydrochloride 0,08 mg/ml
Sodium chloride 0,9% 706

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