Last update :
29/10/2024
Anticancer drug   Daunorubicin/cytarabine liposomale  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Vyxeos France, Germany, Great Britain, United States of America
Compatibility   injection   Compatibility : Daunorubicin/cytarabine liposomale              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Aciclovir sodium
Sodium chloride 0,9% 4654
Unspecified incompatibility Incompatible
injection Daunorubicin/cytarabine liposomale
injection Amikacin sulfate
4354
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
Glucose 5% 4654
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Amikacin sulfate
Sodium chloride 0,9% 4654
Subvisual incompatibility Incompatible
injection Daunorubicin/cytarabine liposomale
injection Amiodarone hydrochloride
4354
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Amoxicillin sodium
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Amoxicillin sodium / clavulanic acid
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Calcium chloride
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Calcium gluconate
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Cefazolin sodium
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Ceftriaxone disodium
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Ciprofloxacin lactate
Sodium chloride 0,9% 4654
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Co-trimoxazole
Sodium chloride 0,9% 4654
Unspecified incompatibility Incompatible
injection Daunorubicin/cytarabine liposomale
injection Co-trimoxazole
4354
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Fluconazole
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Furosemide
Sodium chloride 0,9% 4654
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Gentamicin sulfate
Sodium chloride 0,9% 4654
Subvisual incompatibility Incompatible
injection Daunorubicin/cytarabine liposomale
injection Gentamicin sulfate
4354
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Heparin sodium
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Hydroxyzine dihydrochloride
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Levetiracetam
Sodium chloride 0,9% 4654
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Magnesium chloride
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Meropenem
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Metronidazole
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Midazolam hydrochloride
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Pantoprazole sodium
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Phloroglucinol
Sodium chloride 0,9% 4654
Subvisual incompatibility Incompatible
injection Daunorubicin/cytarabine liposomale
injection Piperacillin sodium / tazobactam
4354
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Piperacillin sodium / tazobactam
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Potassium chloride
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Sodium bicarbonate
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Tranexamic acid
Sodium chloride 0,9% 4654
Unspecified incompatibility Incompatible
injection Daunorubicin/cytarabine liposomale
injection Vancomycin hydrochloride
4354
Immediate turbidity Incompatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
injection Vancomycin hydrochloride
Sodium chloride 0,9% 4654
Compatible
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
Ringer’s lactate solution 4654

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