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References   References 4786  
Type : Poster
Icone.pdf
384Ko
Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Avrillon K, Le Guyader G, Doillet H, Jaskowiec C, Paul M, Poullain S.
Title : Etude de stabilité de solutions de pembrolizumab à 1 et 4 mg/mL à 5 et 25°C dans des poches de NaCl 0,9% en polyoléfine .
Reference : SFPO Congress 2023
Level of Evidence : 
Level of evidence A+
Physical stability : 
Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Protein: intrared spectrometry and second derivative
Protein: ultraviolet spectrometry
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
List of drugs
injectionPembrolizumab Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 1 mg/ml 4°C Not specified
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 4 mg/ml 25°C Not specified
7 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 4 mg/ml 4°C Not specified
30 Day
  Mentions Légales