| Type : |
Journal |
| Web link : |
http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2910 |
|
| Research teams : |
Queensland - Grif!th University, School of Pharmacy |
| Authors : |
Haywood A, Burrell A, van Breda K, Testa C, Norris R. |
| Title : |
Stability of Melatonin in an Extemporaneously Compounded Sublingual Solution and Hard Gelatin Capsule. |
| Reference : |
Int J Pharm Compound ; 13, 2: 170-174. 2009 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
|
List of drugs
 Melatonine
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
1000 mg
|
| Stevia powder |
250 mg |
| Ethanol |
15 ml |
| Fruit aroma |
2 ml |
| Glycerin |
>> 100 ml |
|
24-26°C |
 |
| 90 |
 |
|
|
|
|
|
1000 mg
|
| Stevia powder |
250 mg |
| Ethanol |
15 ml |
| Fruit aroma |
2 ml |
| Glycerin |
>> 100 ml |
|
3-5°C |
|
| 90 |
|
|
|
|
 Melatonine
|
|
|
|
|
|
|
|
|
|
3 mg
|
| Food coloring |
100 mg |
| Methocel E4M® |
100 mg |
| Lactose |
220 mg |
|
24-26°C |
|
| 90 |
|
|
|
|
|
|
3 mg
|
| Food coloring |
100 mg |
| Methocel E4M® |
100 mg |
| Lactose |
220 mg |
|
39-41°C |
|
| 90 |
|
|
|
|
|
