Last update :
19/11/2024
References   References 2707  
Type : Journal
Web link : https://doi.org/10.1046/j.1365-2710.1998.00136.x

Research teams : Singapore - Department of Pharmacy, Faculty of Science, National University of Singapore
Authors : How TH, Loo WY, Yow KL, Lim LY, Chan EW, Ho PC, Chan SY.
Title : Stability of cefazolin sodium eye drops
Reference : J Clin Pharm Ther ; 23, 1: 41-47. 1998

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 

List of drugs
Eye-dropsCefazolin sodium Antibiotic
Factors which affect stability Temperature 25°C Induces Degradation
Stability in solutions Glass Medicine bottle for injection 500 mg
® = Cefazolin panpharma
NaCl 0.45% >> 10 mL
4°C Protect from light
30 Day
Stability in solutions Glass Medicine bottle for injection 500 mg
® = Cefazolin panpharma
Thiomersal 0,5 mg
Glycerin 100 mg
Water for injection >> 10 ml
4°C Protect from light
30 Day

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