Last update :
19/11/2024
References   References 1888  
Type : Journal

Research teams : Alkmaar - Medisch Centrum Alkmaar, Department of clinical pharmacy
Authors : Janknegt R, Van den Berg TJ, De Jong M, Oldenhof HGJ, Steenhoek A.
Title : Compatibility study of midazolam.
Reference : Ziekenhuisfarmacie ; 2: 45-48. 1986

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAminophylline Various
Incompatible 0.72 mg/ml + injectionMidazolam hydrochloride 0.25 & 0.4 mg/ml + Sodium chloride 0,9%
Compatible 0.72 mg/ml + injectionMidazolam hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
injectionAmoxicillin sodium Antibiotic
Incompatible 10 mg/ml + injectionMidazolam hydrochloride 0.05 & 0.4 mg/ml + Sodium chloride 0,9%
injectionCefuroxime sodium Antibiotic
Compatible 7.5 mg/ml + injectionMidazolam hydrochloride 0.05 >> 0.4 mg/ml + Sodium chloride 0,9%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 0.8 mg/ml + injectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Compatible 0.08 mg/ml + injectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
injectionGentamicin sulfate Antibiotic
Compatible 0.8 mg/ml + injectionMidazolam hydrochloride 0.05 >> 0.4 mg/ml + Sodium chloride 0,9%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 0.05 mg/ml + injectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionMidazolam hydrochloride 0.05 >> 0.4 mg/ml + None
injectionMidazolam hydrochloride Anxiolytic
Incompatible 0.25 & 0.4 mg/ml + injectionAminophylline 0.72 mg/ml + Sodium chloride 0,9%
Compatible 0.05 mg/ml + injectionAminophylline 0.72 mg/ml + Sodium chloride 0,9%
Incompatible 0.05 & 0.4 mg/ml + injectionAmoxicillin sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 0.05 >> 0.4 mg/ml + injectionCefuroxime sodium 7.5 mg/ml + Sodium chloride 0,9%
Compatible 0.05 & 0.25 mg/ml + injectionCimetidine hydrochloride 0.8 mg/ml + Sodium chloride 0,9%
Compatible 0.05 & 0.25 mg/ml + injectionFurosemide 0.08 mg/ml + Sodium chloride 0,9%
Compatible 0.05 >> 0.4 mg/ml + injectionGentamicin sulfate 0.8 mg/ml + Sodium chloride 0,9%
Compatible 0.05 & 0.25 mg/ml + injectionHydrocortisone sodium succinate 0.05 mg/ml + Sodium chloride 0,9%
Compatible 0.05 >> 0.4 mg/ml + injectionMetronidazole 5 mg/ml + None
Compatible 0.05 & 0.25 mg/ml + injectionRanitidine hydrochloride 0.4 mg/ml + Sodium chloride 0,9%
Incompatible 0.1 & 0.5 mg/ml + injectionSodium bicarbonate 50 mg/ml + None
Incompatible 0.1 & 0.5 mg/ml + injectionSodium bicarbonate 50 mg/ml + NaHCO3
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0.4 mg/ml + injectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
injectionSodium bicarbonate Electrolyte
Incompatible 50 mg/ml + injectionMidazolam hydrochloride 0.1 & 0.5 mg/ml + None
Incompatible 50 mg/ml + injectionMidazolam hydrochloride 0.1 & 0.5 mg/ml + NaHCO3

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