Last update :
28/04/2024
References   References 1888  
Type : Journal

Research teams : Alkmaar - Medisch Centrum Alkmaar, Department of clinical pharmacy
Authors : Janknegt R, Van den Berg TJ, De Jong M, Oldenhof HGJ, Steenhoek A.
Title : Compatibility study of midazolam.
Reference : Ziekenhuisfarmacie ; 2: 45-48. 1986

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAminophylline Various
Incompatible 0.72 mg/ml + InjectionMidazolam hydrochloride 0.25 & 0.4 mg/ml + Sodium chloride 0,9%
Compatible 0.72 mg/ml + InjectionMidazolam hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
InjectionAmoxicillin sodium Antibiotic
Incompatible 10 mg/ml + InjectionMidazolam hydrochloride 0.05 & 0.4 mg/ml + Sodium chloride 0,9%
InjectionCefuroxime sodium Antibiotic
Compatible 7.5 mg/ml + InjectionMidazolam hydrochloride 0.05 >> 0.4 mg/ml + Sodium chloride 0,9%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 0.8 mg/ml + InjectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Compatible 0.08 mg/ml + InjectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
InjectionGentamicin sulfate Antibiotic
Compatible 0.8 mg/ml + InjectionMidazolam hydrochloride 0.05 >> 0.4 mg/ml + Sodium chloride 0,9%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 0.05 mg/ml + InjectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionMidazolam hydrochloride 0.05 >> 0.4 mg/ml + None
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 0.25 & 0.4 mg/ml + InjectionAminophylline 0.72 mg/ml + Sodium chloride 0,9%
Compatible 0.05 mg/ml + InjectionAminophylline 0.72 mg/ml + Sodium chloride 0,9%
Incompatible 0.05 & 0.4 mg/ml + InjectionAmoxicillin sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 0.05 >> 0.4 mg/ml + InjectionCefuroxime sodium 7.5 mg/ml + Sodium chloride 0,9%
Compatible 0.05 & 0.25 mg/ml + InjectionCimetidine hydrochloride 0.8 mg/ml + Sodium chloride 0,9%
Compatible 0.05 & 0.25 mg/ml + InjectionFurosemide 0.08 mg/ml + Sodium chloride 0,9%
Compatible 0.05 >> 0.4 mg/ml + InjectionGentamicin sulfate 0.8 mg/ml + Sodium chloride 0,9%
Compatible 0.05 & 0.25 mg/ml + InjectionHydrocortisone sodium succinate 0.05 mg/ml + Sodium chloride 0,9%
Compatible 0.05 >> 0.4 mg/ml + InjectionMetronidazole 5 mg/ml + None
Compatible 0.05 & 0.25 mg/ml + InjectionRanitidine hydrochloride 0.4 mg/ml + Sodium chloride 0,9%
Incompatible 0.1 & 0.5 mg/ml + InjectionSodium bicarbonate 50 mg/ml + None
Incompatible 0.1 & 0.5 mg/ml + InjectionSodium bicarbonate 50 mg/ml + NaHCO3
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0.4 mg/ml + InjectionMidazolam hydrochloride 0.05 & 0.25 mg/ml + Sodium chloride 0,9%
InjectionSodium bicarbonate Electrolyte
Incompatible 50 mg/ml + InjectionMidazolam hydrochloride 0.1 & 0.5 mg/ml + None
Incompatible 50 mg/ml + InjectionMidazolam hydrochloride 0.1 & 0.5 mg/ml + NaHCO3

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