Last update :
18/04/2024
References   References 108  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/53/19/2309

Research teams : Raritan - Johnson & Johnson Pharmaceutical Research & Development
Authors : Williams NA, Bornstein M, Johnson K.
Title : Stability of levofloxacin in intravenous solutions in polyvinyl chloride bags.
Reference : Am J Health-Syst Pharm ; 53: 2309-2313. 1996

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionLevofloxacine Antibiotic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 5 mg/ml -20°C Protect from light
182 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 5 mg/ml 25°C Protect from light
3 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 5 mg/ml 5°C Protect from light
14 Day

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