Last update :
08/11/2024
References   References 317  
Type : Journal

Research teams : Royal Oak - William Beaumont Hospital, Department of Pharmacy
Authors : Kershaw BP, Monnier HL, Mason JH.
Title : Visual compatibility of premixed theophylline or heparin with selected drugs for IV administration.
Reference : Am J Hosp Pharm ; 50: 1360-1362. 1993

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 20 mg/ml + injectionTheophylline 4 mg/ml + None
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 30 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 30 mg/ml + injectionTheophylline 4 mg/ml + None
injectionAztreonam Antibiotic
Compatible 20 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 20 mg/ml + injectionTheophylline 4 mg/ml + None
injectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 20 mg/ml + injectionTheophylline 4 mg/ml + None
injectionCeftazidime Antibiotic
Compatible 20 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 20 mg/ml + injectionTheophylline 4 mg/ml + None
injectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 20 mg/ml + injectionTheophylline 4 mg/ml + None
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 6 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 6 mg/ml + injectionTheophylline 4 mg/ml + None
injectionClindamycin phosphate Antibiotic
Compatible 12 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 12 mg/ml + injectionTheophylline 4 mg/ml + None
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.08 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 0.08 mg/ml + injectionTheophylline 4 mg/ml + None
injectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 1 mg/ml + injectionTheophylline 4 mg/ml + None
injectionDopamine hydrochloride Cardiotonic
Compatible 1.6 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 1.6 mg/ml + injectionTheophylline 4 mg/ml + None
injectionDoxycycline hyclate Antibiotic
Incompatible 1 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 1 mg/ml + injectionTheophylline 4 mg/ml + None
injectionErythromycin lactobionate Antibiotic
Compatible 3.3 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 3.3 mg/ml + injectionTheophylline 4 mg/ml + None
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 2 mg/ml + injectionTheophylline 4 mg/ml + None
injectionGentamicin sulfate Antibiotic
Incompatible 2 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 2 mg/ml + injectionTheophylline 4 mg/ml + None
injectionHeparin sodium Anticoagulant
Compatible 50 UI/ml + injectionAmpicillin sodium 20 mg/ml + None
Compatible 50 UI/ml + injectionAmpicillin sodium - sulbactam sodium 30 mg/ml + None
Compatible 50 UI/ml + injectionAztreonam 20 mg/ml + None
Compatible 50 UI/ml + injectionCefazolin sodium 20 mg/ml + None
Compatible 50 UI/ml + injectionCeftazidime 20 mg/ml + None
Compatible 50 UI/ml + injectionCeftriaxone disodium 20 mg/ml + None
Compatible 50 UI/ml + injectionCimetidine hydrochloride 6 mg/ml + None
Compatible 50 UI/ml + injectionClindamycin phosphate 12 mg/ml + None
Compatible 50 UI/ml + injectionDexamethasone sodium phosphate 0.08 mg/ml + None
Compatible 50 UI/ml + injectionDobutamine hydrochloride 1 mg/ml + None
Compatible 50 UI/ml + injectionDopamine hydrochloride 1.6 mg/ml + None
Incompatible 50 UI/ml + injectionDoxycycline hyclate 1 mg/ml + None
Compatible 50 UI/ml + injectionErythromycin lactobionate 3.3 mg/ml + None
Compatible 50 UI/ml + injectionFluconazole 2 mg/ml + None
Incompatible 50 UI/ml + injectionGentamicin sulfate 2 mg/ml + None
Compatible 50 UI/ml + injectionHydrocortisone sodium succinate 2 mg/ml + None
Compatible 50 UI/ml + injectionLidocaine hydrochloride 4 mg/ml + None
Compatible 50 UI/ml + injectionMethylprednisolone sodium succinate 2.5 mg/ml + None
Compatible 50 UI/ml + injectionMetronidazole 5 mg/ml + None
Compatible 50 UI/ml + injectionNafcillin sodium 20 mg/ml + None
Incompatible 50 UI/ml + injectionNitroglycerin 0.2 mg/ml + None
Compatible 50 UI/ml + injectionNitroprusside sodium 0.2 mg/ml + None
Compatible 50 UI/ml + injectionPenicillin G potassium 0.04 MUI/ml + None
Incompatible 50 UI/ml + injectionPhenytoin sodium 2 mg/ml + None
Compatible 50 UI/ml + injectionPiperacillin sodium 60 mg/ml + None
Compatible 50 UI/ml + injectionPotassium chloride 200 mEq/l + None
Compatible 50 UI/ml + injectionRanitidine hydrochloride 1 mg/ml + None
Compatible 50 UI/ml + injectionTheophylline 4 mg/ml + None
Compatible 50 UI/ml + injectionTicarcillin / clavulanic acid 31 mg/ml + None
Incompatible 50 UI/ml + injectionTobramycin sulfate 0.8 mg/ml + None
Incompatible 50 UI/ml + injectionVancomycin hydrochloride 6.6 mg/ml + None
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 2 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 2 mg/ml + injectionTheophylline 4 mg/ml + None
injectionLidocaine hydrochloride Local anesthetic
Compatible 4 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 4 mg/ml + injectionTheophylline 4 mg/ml + None
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 2.5 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 2.5 mg/ml + injectionTheophylline 4 mg/ml + None
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 5 mg/ml + injectionTheophylline 4 mg/ml + None
injectionNafcillin sodium Antibiotic
Compatible 20 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 20 mg/ml + injectionTheophylline 4 mg/ml + None
injectionNitroglycerin Vasodilator
Incompatible 0.2 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 0.2 mg/ml + injectionTheophylline 4 mg/ml + None
injectionNitroprusside sodium Vasodilator
Compatible 0.2 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 0.2 mg/ml + injectionTheophylline 4 mg/ml + None
injectionPenicillin G potassium Antibiotic
Compatible 0.04 MUI/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 0.04 MUI/ml + injectionTheophylline 4 mg/ml + None
injectionPhenytoin sodium Antiepileptic
Incompatible 2 mg/ml + injectionHeparin sodium 50 UI/ml + None
Incompatible 2 mg/ml + injectionTheophylline 4 mg/ml + None
injectionPiperacillin sodium Antibiotic
Compatible 60 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 60 mg/ml + injectionTheophylline 4 mg/ml + None
injectionPotassium chloride Electrolyte
Compatible 200 mEq/l + injectionHeparin sodium 50 UI/ml + None
Compatible 200 mEq/l + injectionTheophylline 4 mg/ml + None
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 1 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 1 mg/ml + injectionTheophylline 4 mg/ml + None
injectionTheophylline Various
Compatible 4 mg/ml + injectionAmpicillin sodium 20 mg/ml + None
Compatible 4 mg/ml + injectionAmpicillin sodium - sulbactam sodium 30 mg/ml + None
Compatible 4 mg/ml + injectionAztreonam 20 mg/ml + None
Compatible 4 mg/ml + injectionCefazolin sodium 20 mg/ml + None
Compatible 4 mg/ml + injectionCeftazidime 20 mg/ml + None
Compatible 4 mg/ml + injectionCeftriaxone disodium 20 mg/ml + None
Compatible 4 mg/ml + injectionCimetidine hydrochloride 6 mg/ml + None
Compatible 4 mg/ml + injectionClindamycin phosphate 12 mg/ml + None
Compatible 4 mg/ml + injectionDexamethasone sodium phosphate 0.08 mg/ml + None
Compatible 4 mg/ml + injectionDobutamine hydrochloride 1 mg/ml + None
Compatible 4 mg/ml + injectionDopamine hydrochloride 1.6 mg/ml + None
Compatible 4 mg/ml + injectionDoxycycline hyclate 1 mg/ml + None
Compatible 4 mg/ml + injectionErythromycin lactobionate 3.3 mg/ml + None
Compatible 4 mg/ml + injectionFluconazole 2 mg/ml + None
Compatible 4 mg/ml + injectionGentamicin sulfate 2 mg/ml + None
Compatible 4 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 4 mg/ml + injectionHydrocortisone sodium succinate 2 mg/ml + None
Compatible 4 mg/ml + injectionLidocaine hydrochloride 4 mg/ml + None
Compatible 4 mg/ml + injectionMethylprednisolone sodium succinate 2.5 mg/ml + None
Compatible 4 mg/ml + injectionMetronidazole 5 mg/ml + None
Compatible 4 mg/ml + injectionNafcillin sodium 20 mg/ml + None
Compatible 4 mg/ml + injectionNitroglycerin 0.2 mg/ml + None
Compatible 4 mg/ml + injectionNitroprusside sodium 0.2 mg/ml + None
Compatible 4 mg/ml + injectionPenicillin G potassium 0.04 MUI/ml + None
Incompatible 4 mg/ml + injectionPhenytoin sodium 2 mg/ml + None
Compatible 4 mg/ml + injectionPiperacillin sodium 60 mg/ml + None
Compatible 4 mg/ml + injectionPotassium chloride 200 mEq/l + None
Compatible 4 mg/ml + injectionRanitidine hydrochloride 1 mg/ml + None
Compatible 4 mg/ml + injectionTicarcillin / clavulanic acid 31 mg/ml + None
Compatible 4 mg/ml + injectionTobramycin sulfate 0.8 mg/ml + None
Compatible 4 mg/ml + injectionVancomycin hydrochloride 6.6 mg/ml + None
injectionTicarcillin / clavulanic acid Antibiotic
Compatible 31 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 31 mg/ml + injectionTheophylline 4 mg/ml + None
injectionTobramycin sulfate Antibiotic
Incompatible 0.8 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 0.8 mg/ml + injectionTheophylline 4 mg/ml + None
injectionVancomycin hydrochloride Antibiotic
Incompatible 6.6 mg/ml + injectionHeparin sodium 50 UI/ml + None
Compatible 6.6 mg/ml + injectionTheophylline 4 mg/ml + None

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