Last update :
14/12/2024
References   References 295  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Yamashita SK, Walker SE, Choudhury T, Iazzetta J.
Title : Compatibility of selected critical care drugs during Y-site administration.
Reference : Am J Health-Syst Pharm ; 53: 1048-1051. 1996

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 4.8 mg/ml + injectionEsmolol hydrochloride 40 mg/ml + Glucose 5%
Compatible 4.8 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 4.8 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 4.8 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 4.8 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Incompatible 4 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 4 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 4 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Incompatible 3.2 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 3.2 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 3.2 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
injectionEsmolol hydrochloride Beta-blocker
Compatible 40 mg/ml + injectionAmiodarone hydrochloride 4.8 mg/ml + Glucose 5%
Compatible 40 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 40 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 40 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 40 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + injectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Incompatible 100 UI/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Incompatible 100 UI/ml + injectionNitroglycerin 1,6 >> 3,25 mg/ml + Glucose 5%
Compatible 100 UI/ml + injectionNitroprusside sodium 0.2 mg/ml + Glucose 5%
injectionInsulin Glucose-lowering
Compatible 1 UI/ml + injectionAmiodarone hydrochloride 4.8 mg/ml + Glucose 5%
Incompatible 1 UI/ml + injectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 1 UI/ml + injectionEsmolol hydrochloride 40 mg/ml + Glucose 5%
Incompatible 1 UI/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 UI/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 UI/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 UI/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%
Compatible 1 UI/ml + injectionNitroprusside sodium 0.2 mg/ml + Glucose 5%
Incompatible 1 UI/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
injectionLabetalol hydrochloride Beta-blocker
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 4.8 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionEsmolol hydrochloride 40 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Incompatible 5 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 5 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionNitroprusside sodium 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 4.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionEsmolol hydrochloride 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 1 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionNitroprusside sodium 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 4.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 1 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionNitroprusside sodium 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
injectionNitroglycerin Vasodilator
Incompatible 1,6 >> 3,25 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
injectionNitroprusside sodium Vasodilator
Compatible 0.2 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.064 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.064 mg/ml + injectionEsmolol hydrochloride 40 mg/ml + Glucose 5%
Incompatible 0.064 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 0.064 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 0.064 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.064 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%

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