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Antibiotic   Ceftolozane / tazobactam  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Zepilen Spain
Zerbaxa Argentina, Chile, Ecuador, France, Germany, Great Britain, Mexico, Peru, Romania, Spain, Switzerland, United States of America
Stability in solutions   injection   Stability in solutions : Ceftolozane / tazobactam     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 87.7 / 43.8 mg/ml 2-8°C Not specified
4 Day
3803
Manufacturer's stability data
Glass Sodium chloride 0,9% 87.7 / 43.8 mg/ml 2-8°C Not specified
4 Day
3803
Manufacturer's stability data
Polyvinyl chloride Extraneal® (Baxter) 0.02/0.01 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Extraneal® (Baxter) 0.02/0.01 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Physionéal® 1.36 (Baxter) 0.055/0.027 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Physionéal® 1.36 (Baxter) 0.055/0.027 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Physionéal® 2.27 (Baxter) 0.055/0.027 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Physionéal® 2.27 (Baxter) 0.055/0.027 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Physionéal® 3.86 (Baxter) 0.055/0.027 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Physionéal® 3.86 (Baxter) 0.055/0.027 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Dianéal® 1.5% glucose (Baxter) 0.02/0.01 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Dianéal® 1.5% glucose (Baxter) 0.02/0.01 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Dianéal® 2.5% glucose (Baxter) 0.02/0.01 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Dianéal® 2.5% glucose (Baxter) 0.02/0.01 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Dianéal® 4.25% glucose (Baxter) 0.02/0.01 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Dianéal® 4.25% glucose (Baxter) 0.02/0.01 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Balance® 1.3% Frésénius 0.04/0.02 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Balance® 1.3% Frésénius 0.04/0.02 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polyvinyl chloride Balance® 2.5% Frésénius 0.04/0.02 mg/ml 37°C Not specified
12 Hour
4378
Level of evidence A+
Polyvinyl chloride Balance® 2.5% Frésénius 0.04/0.02 mg/ml 4°C Not specified
168 Hour
4378
Level of evidence A+
Polypropylen Syringe NaCl 0,9% or Glucose 5% 62,5/31,25 mg/ml 20-25°C Light
48 Hour
4634
Level of evidence C+
Polyisoprene elastomer Sodium chloride 0,9% 13.33/6.66 mg/ml 32°C Protect from light
18 Hour
4645
Level of evidence C+
Polyisoprene elastomer Sodium chloride 0,9% 13.33/6.66 mg/ml 8°C Protect from light
8 Day
4645
Level of evidence C+
Polyisoprene elastomer Sodium chloride 0,9% 25/12,5 mg/ml 37°C Protect from light
12 Hour
4634
Level of evidence C+
Polyisoprene elastomer Sodium chloride 0,9% 3.33/1.66 mg/ml 32°C Protect from light
18 Hour
4645
Level of evidence C+
Polyisoprene elastomer Sodium chloride 0,9% 3.33/1.66 mg/ml 8°C Protect from light
8 Day
4645
Level of evidence C+
Polyisoprene elastomer Glucose 5% 25/12,5 mg/ml 37°C Protect from light
8 Hour
4634
Level of evidence C+
Silicone elastomer Sodium chloride 0,9% 13.33/6.66 mg/ml 32°C Protect from light
18 Hour
4645
Level of evidence C+
Silicone elastomer Sodium chloride 0,9% 13.33/6.66 mg/ml 8°C Protect from light
8 Day
4645
Level of evidence C+
Silicone elastomer Sodium chloride 0,9% 3.33/1.66 mg/ml 32°C Protect from light
18 Hour
4645
Level of evidence C+
Silicone elastomer Sodium chloride 0,9% 3.33/1.66 mg/ml 8°C Protect from light
8 Day
4645
Level of evidence C+
Not specified NaCl 0,9% or Glucose 5% 10 / 5 mg/ml 2-8°C Not specified
7 Day
3803
Manufacturer's stability data
Not specified NaCl 0,9% or Glucose 5% 10 / 5 mg/ml 25°C Not specified
24 Hour
3803
Manufacturer's stability data
  Mentions Légales