Last update :
14/12/2024
Anticancer drug   Vincristine sulfate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Cellecristin Germany
Citomid Chile, Colombia, Mexico, Peru
Crisovin Colombia, Ecuador, Mexico
Cytocristin Malaysia
DBL vincristine sulfate Malaysia, New Zealand
Farmistin Germany
Marqibo United States of America
Nefixol Mexico
Oncocristin Colombia
Oncovin Austria, Colombia, Denmark, Finland, France, Great Britain, Luxembourg, Mexico, Morocco, Saudi Arabia, Sweden, Switzerland, United Arab Emirates
Onkocristin Germany
Sindovin Iran
Sulfato de vincristine Venezuela
Unicristin Peru
Vinblax Mexico
Vincasar Mexico, United States of America
Vincrisin Belgium
Vincristin Austria, Germany, Hungary, Switzerland
Vincristina Argentina, Chile, Colombia, Ecuador, Iceland, Iran, Italy, Peru, Spain, Venezuela
Vincristine France, Greece, Luxembourg, Malaysia, Morocco, Norway, Sweden, Switzerland, Tunisia, Turkey
Vincristine sulfat Turkey
Vincristine sulfate Canada, United States of America
Vincristine sulphate Egypt, Great Britain, Ireland, Malaysia, New Zealand, Poland, United Arab Emirates
Vincristinesulfaat Netherlands
Vincristinum Luxembourg
Vincrisul Spain
Vinlon Lyo Peru
Vinracine Egypt, Malaysia
Vintec Mexico
Compatibility   injection   Compatibility : Vincristine sulfate              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 99
Unspecified incompatibility Incompatible
injection Vincristine sulfate
injection Calcium gluconate
3644
Compatible
injection Vincristine sulfate 0,05 mg/ml
injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Chemical instability Incompatible
injection Vincristine sulfate
injection Cisplatin
3578
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Vincristine sulfate 0.004 mg/ml
injection Cytarabine 0.016 mg/ml
Glucose 5% 431
Compatible
injection Vincristine sulfate 0,036 mg/ml
injection Doxorubicin hydrochloride 1,67 mg/ml
Sodium chloride 0,9% 32
Compatible
injection Vincristine sulfate 0,033 mg/ml
injection Doxorubicin hydrochloride 1,4 mg/ml
Sodium chloride 0,9% 408
Compatible
injection Vincristine sulfate 0,033 mg/ml
injection Doxorubicin hydrochloride 1,4 mg/ml
NaCl 0,45% Glucose 2,5% 408
Compatible
injection Vincristine sulfate 1 mg/ml
injection Doxorubicin hydrochloride 2 mg/ml
763
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
injection Vincristine sulfate 1 mg/ml
injection Droperidol 2,5 mg/ml
763
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
injection Vincristine sulfate 1 mg/ml
injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
injection Vincristine sulfate 1 mg/ml
injection Fluorouracil 50 mg/ml
763
Compatible
injection Vincristine sulfate 0.004 mg/ml
injection Fluorouracil 0.010 mg/ml
Glucose 5% 431
Compatible
injection Vincristine sulfate 1 mg/ml
injection Folinate calcium 10 mg/ml
763
Immediate precipitation Incompatible
injection Vincristine sulfate 1 mg/ml
injection Furosemide 10 mg/ml
763
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Vincristine sulfate 0.01 & 0.34 mg/ml
injection Granisetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 57
Compatible
injection Vincristine sulfate 1 mg/ml
injection Heparin sodium 1000 UI/ml
763
Color change Incompatible
injection Vincristine sulfate 1 mg/ml
injection Idarubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Immediate precipitation Incompatible
injection Vincristine sulfate 0.05 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
injection Vincristine sulfate 0.1 mg/ml
injection Methotrexate sodium 30 mg/ml
Sodium chloride 0,9% 150
Compatible
injection Vincristine sulfate 0.004 mg/ml
injection Methotrexate sodium 0.008 mg/ml
Glucose 5% 431
Compatible
injection Vincristine sulfate 1 mg/ml
injection Methotrexate sodium 25 mg/ml
763
Compatible
injection Vincristine sulfate 1 mg/ml
injection Metoclopramide hydrochloride 5 mg/ml
763
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
injection Vincristine sulfate 0,05 mg/ml
injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Paclitaxel 1.2 mg/ml
Glucose 5% 248
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Precipitation after 30 minutes Incompatible
injection Vincristine sulfate 0.1 mg/ml
injection Sodium bicarbonate 14 mg/ml
None 150
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
injection Vincristine sulfate 1 mg/ml
injection Topotecan 0.056 mg/ml
NaCl 0,9% or Glucose 5% 1026
Compatible
injection Vincristine sulfate 1 mg/ml
injection Vinblastine sulfate 1 mg/ml
763
Compatible
injection Vincristine sulfate 0.05 mg/ml
injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Precipitation after 30 minutes Incompatible
injection Vincristine sulfate 0.1 mg/ml
NaHCO3 150

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