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19/11/2024
抗癌藥物   Paclitaxel  
注射液
溶液稳定性 混合物稳定性 影响稳定性的因素 兼容性 用药途径 引用文献 PDF
   化学式  

商品名   商品名     

商品名仅供参考, 药品所用的辅料可能依国家或厂商不同有所不同。

Aclipak 马来西亚
Acoexcel 墨西哥
Actaxel 瑞典
Acupaxil 秘鲁
Anzatax 土耳其, 沙特阿拉伯, 阿联酋
Aritaxel 德国
Cantaxel 印度
Clitaxel 阿根廷
Dalys 阿根廷
Difren 阿根廷
Ebetaxel 奥地利, 沙特阿拉伯
Genexol 匈牙利
Onxol 美国
Paclinova 阿根廷
Paclired 巴西
Paclitaxin 荷兰
Parexel 厄瓜多尔
Paxene 丹麦, 希腊, 芬兰, 西班牙
Poltaxel 波兰
Ribotax 德国
Taxol 丹麦, 克罗地亚, 匈牙利, 卢森堡, 哥伦比亚, 土耳其, 埃及, 奥地利, 委内瑞拉, 希腊, 德国, 意大利, 摩洛哥, 新西蘭, 日本, 比利时, 法国, 波兰, 澳大利亚, 爱尔兰, 瑞典, 瑞士, 秘鲁, 美国, 芬兰, 英国, 葡萄牙, 西班牙, 阿联酋, 马来西亚
Taxomedac 德国
Vitax 土耳其
引用文献   注射液   引用文献 : Paclitaxel  
种类 出版物
38 文献 Allwood MC, Martin HJ.
The extraction of diethylhexylphtalate (DEHP) from polyvinyl chloride components of intravenous infusion containers and administration sets by paclitaxel injection.
Int J Pharm 1996 ; 127: 65-71.
47 文献 Burm JP, Jhee SS, Chin A, Moon YSK.
Stability of paclitaxel with ondansetron or ranitidine hydrochloride during simulated Y site administration.
Am J Hosp Pharm 1994 ; 51: 1201-1204.
57 文献 Mayron D, Gennaro AR.
Stability and compatibility of granisetron hydrochloride in IV solutions and oral liquids and during simulated Y-site injection with selected drugs.
Am J Health-Syst Pharm 1996 ; 53: 294-304.
85 文献 Trissel LA, Bready BB.
Turbidimetric assessment of the compatibility of taxol with selected other drugs during simulated Y-site injection.
Am J Hosp Pharm 1992 ; 49: 1716-1719.
140 文献 Pearson SD, Trissel LA.
Leaching of diethylhexyl phthalate from polyvinyl chloride containers by selected drugs and formulation components.
Am J Hosp Pharm 1993 ; 50: 1405-1409.
151 文献 Burm JP, Choi JS, Jhee SS, Chin A, Ulrich RW, Gill MA.
Stability of paclitaxel and fluconazole during simulated Y-site administration.
Am J Hosp Pharm 1994 ; 51: 2704-2706.
157 文献 Xu QA, Trissel LA, Martinez JF.
Stability of paclitaxel in 5% dextrose injection or 0.9% sodium chloride injection at 4, 22, or 32°C.
Am J Hosp Pharm 1994 ; 51: 3058-3060.
158 文献 Trissel LA, Xu QA, Kwan J, Martinez JF.
Compatibility of paclitaxel injection vehicle with intravenous administration and extension sets.
Am J Hosp Pharm 1994 ; 51: 2804-2810.
173 文献 Williams DA, Naik A.
Precipitation of paclitaxel from continuous infusion fluids.
J Infus Chemother 1994 ; 4: 140-142.
182 文献 Trissel LA, Gilbert DL, Martinez JF.
Compatibility of granisetron hydrochloride with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 56-60.
248 文献 Trissel LA, Martinez JF.
Turbidimetric assessment of the compatibility of taxol with 42 other drugs during simulated Y-site injection.
Am J Hosp Pharm 1993 ; 50: 300-304.
249 文献 Trissel LA, Martinez JF.
Compatibility of thiotepa (lyophilized) with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1996 ; 53: 1041-1045.
250 文献 Mazzo DJ, Nguyen-Huu JJ, Pagniez S, Denis P.
Compatibility of docetaxel and paclitaxel in intravenous solutions with polyvinyl chloride infusion materials.
Am J Health-Syst Pharm 1997 ; 54: 566-569.
251 文献 Trissel LA, Gilbert DL, Martinez JF.
Compatibility of doxorubicin hydrochloride liposome injection with selected other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 2708-2713.
300 文献 Trissel LA, Gilbert DL, Martinez JF.
Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 1287-1292.
301 文献 Trissel LA, Gilbert DL, Martinez JF, Baker MB, Walter WV, Mirtallo JM.
Compatibility of parenteral nutrient solutions with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 1295-1300.
412 文献 Waugh WN, Trissel LA, Stella VJ.
Stability, compatibility, and plasticizer extraction of taxol (NSC-125973) injection diluted in infusion solutions and stored in various containers.
Am J Hosp Pharm 1991 ; 48: 1520-1524.
669 文献 Chin A, Ramakrishnan RR, Yoshimura NN, Jeong EWS, Nii LJ, DiMeglio LS.
Paclitaxel stability and compatibility in polyolefin containers.
Ann Pharmacotherapy 1994 ; 28: 35-36.
872 文献 Zhang YP, Xu QA, Trissel LA, Gilbert DL, Martinez F.
Compatibility and stability of paclitaxel combined with cisplatin and with carboplatin in infusion solutions.
Ann Pharmacotherapy 1997 ; 31: 1465-1470.
921 文献 Trissel LA, Gilbert DL, Martinez JF.
Incompatibility and compatibility of amphotericin B cholesteryl sulfate complex with selected other drugs during simulated Y-site administration.
Hosp Pharm 1998 ; 33: 284-292.
1026 文献 Mayron D, Gennaro AR.
Stability and compatibility of topotecan hydrochloride with selected drugs.
Am J Health-Syst Pharm 1999 ; 56: 875-881.
1286 文献 Trissel LA, Xu QA, Gilbert DL.
Compatibility and stability of paclitaxel combined with doxorubicin hydrochloride in infusion solutions.
Ann Pharmacotherapy 1998 ; 32: 1013-1016.
1410 文献 Trissel LA, Martinez JF, Simmons M.
Compatibility of etoposide phosphate with selected drugs during simulated Y-site injection.
J Am Pharm Assoc 1999 ; 39: 141-145.
1415 文献 Trissel L.A, Gilbert D.L, Martinez J.F, Baker M.B, Walter W.V, Mirtallo J.M.
Compatibility of medications with 3-in-1 parenteral nutrition admixtures.
JPEN 1999 ; 23: 67-74.
1423 文献 Trissel LA, Martinez JF, Gilbert DL.
Compatibility of gemcitabine hyrochloride with 107 selected drugs during simulated Y-site injection.
J Am Pharm Assoc 1999 ; 39: 514-518.
1496 文献 Trissel LA, Martinez JF, Gilbert DL.
Screening cladribine for Y-site physical compatibility with selected drugs.
Hosp Pharm 1996 ; 31: 1425-1428.
1520 实验室 Etude de stabilité des médicaments en Ecoflac®
B Braun 2001
1522 实验室 Macoflex N®
Maco Pharma 2001
1625 文献 Trissel LA, Saenz C, Williams YW, Ingram D.
Incompatibilities of lansoprazole injection with other drugs during simulated Y-site coadministration.
Int J Pharm Compound 2001 ; 5: 314-321.
1662 文献 Trissel LA, Saenz CA, Ingram DS, Ogundele AB.
Compatibility screening of oxaliplatin during simulated Y-site administration with other drugs.
J Oncol Pharm Practice 2002 ; 8: 33-37.
1741 文献 Pfeifer RW, Hale KN, Cronquist SE, Daniels M.
Precipitation of paclitaxel during infusion by pump.
Am J Hosp Pharm 1993 ; 50: 2518-2521.
1865 文献 Sautou-Miranda V, Brigas F, Vanheerswinghels S, Chopineau J.
Compatibility of paclitaxel in 5% glucose solution with ECOFLAC® low-density polyethylene containers - Stability under different storage conditions.
Int J Pharm 1999 ; 178: 77-82.
1925 文献 Trissel LA , Williams KY, Gilbert DL.
Compatibility screening of linezolid injection during simulated Y-site administration with other drugs and infusion solutions.
J Am Pharm Assoc 2000 ; 40: 515-519.
1940 文献 Xu QA, Trissel LA.
Stability of palonosetron hydrochloride with paclitaxel and docetaxel during simulated Y-site administration.
Am J Health-Syst Pharm 2004 ; 61: 1596-1598.
1953 文献 Trissel LA, Saenz CA, Ogundele AB, Ingram DS.
Physical compatibility of pemetrexed disodium with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2004 ; 61: 2289-2293.
1956 实验室 Paclitaxel - Summary of Product Characteristics
Hospira UK Limited 2015
1961 文献 Kim SC, Yoon HJ, Lee JW, Yu J, Park ES, Chi SC.
Investigation of the release behavior of DEHP from infusion sets by paclitaxel-loaded polymeric micelles.
Int J Pharm 2005 ; 293: 303-310.
1982 文献 Trissel LA, Ogundele AB.
Compatibility of anidulafungin with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2005 ; 62: 834-837.
2014 文献 Pourroy B, Botta C, Solas C, Lacarelle B, Braguer D.
Seventy-two-hour stability of Taxol® in 5% dextrose or 0.9% sodium chloride in Viaflo®, Freeflex®, Ecoflac® and Macoflex N® non PVC bags.
J Clin Pharm Ther 2005 ; 30: 455-458.
2172 文献 Donyai P, Sewell GJ.
Physical and chemical stability of paclitaxel infusions in different container types.
J Oncol Pharm Practice 2006 ; 12, 4: 211-222.
2174 文献 Kattige A.
Long-term physical and chemical stability of a generic paclitaxel infusion under simulated storage and clinical-use conditions.
EJHP Science 2006 ; 12, 6: 129-134.
2262 文献 Brammer MK, Chan P, Heatherly K, Trusley C, Kupiec TC, Trissel LA, Psathas PA, Gilmor T, Schaufelberger D.
Compatibility of doripenem with other drugs during simulated Y-site administratioN
Am J Health-Syst Pharm 2008 ; 65: 1261-1265.
2344 实验室 Stabilité physico-chimique de la gamme oncologie Ebewe Pharma France après dilution.
Ebewe Pharma 2009
3093 文献 Tian J, Stella VJ.
Degradation of paclitaxel and related compounds in aqueous solutions III: Degradation under acidic pH conditions and overall kinetics
J Pharm Sci 2010 ; 99, 3 : 1288-1298.
3277 文献 Yang Z, Cameron S, Paul H.
Stability of Carboplatin, Paclitaxel, and Docetaxel with Acetyl-L-carnitine During Simulated Y-site Administration.
Int J Pharm Compound 2012 ; 16, 1 : 82-85.
3578 实验室 Cisplatin - Summary of Product Characteristics
Accord Healthcare 2011

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