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Immunosuppressant   Tacrolimus  
Oral solution
Eye-drops injection
Stability of pharmaceutical preparations Stability of mixtures Factors which affect stability Compatibility References pdf
   Chemical structure  

Oral solution
References   Oral solution   References : Tacrolimus  
Type Publication
2436 Journal Jacobson PA, Johnson CE, West NJ, Foster JA.
Stability of tacrolimus in an extemporaneously compounded oral liquid
Am J Health-Syst Pharm 1997 ; 54: 178-180.
2789 Journal Elefante A, Muindi J, West K, Dunford L, Abel S, Paplham P, Brown K, Hahn T, Padmanabhan S, Battiwalla M, McCarthy PL.
Long-term stability of a patient-convenient 1mg/ml suspension of tacrolimus for accurate maintenance of stable therapeutic levels.
Bone Marrow Transplantation 2006 ; 37, 8: 781-784.
3846 Journal Polonini HC, Silva SL, Cunha CN, Brand?o MAF, Ferreira AO.
Compatibility of cholecalciferol, haloperidol, imipramine hydrochloride, levodopa/carbidopa, lorazepam, minocycline hydrochloride, tacrolimus monohydrate, terbinafine, tramadol hydrochloride and valsartan in SyrSpend® SF PH4 oral suspensions.
Pharmazie 2016 71: 185?191.
3946 Journal Friciu M, Zaraa S, Leclair G.
Stability of Extemporaneously Compounded Tacrolimus in Glass Bottles and Plastic Syringes
Can J Hosp Pharm 2017 ; 70,1 :51-53.
4177 Journal Polonini H, Loures da Silva S, Fernandes Brandao M.A, Bauters T, De Moerloose B, De Oliveira Ferreira A.
Compatibility of Baclofen, Carvedilol, Hydrochlorothiazide, Mercaptopurine, Methadone Hydrochloride, Oseltamivir Phosphate, Phenobarbital, Propranolol Hydrochloride, Pyrazinamide, Sotalol Hydrochloride, Spironolactone, Tacrolimus Monohydrate, Ursodeoxycholic Acid, and Vancomycin Hydrochloride Oral Suspensions Compounded with SyrSpend SF PH4.
Int J Pharm Compound 2018 ;22,6:516-526
4673 Journal Barrieu M, Chennell P, Yessaad M, Bouattour Y, Wasiak M, Jouannet M, Le Basle Y, Sautou V.
Physicochemical Stability of a Novel Tacrolimus Ophtalmic Formulation for the Treatment of Ophtalmic Inflammatory Diseases.
Pharmaceutics 2022 ;14,1:118
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