Last update :
19/11/2024
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Analgesic   Nefopam  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Acupan France, Great Britain, Ireland, Italy, Luxembourg, Morocco, North Ireland, Poland, Romania, Tunisia
Nefam Italy
Nefomed Tunisia
Nefopam Egypt, Poland
Nephentil Mexico
Nopain Egypt
Oxadol Italy
Painstop Saudi Arabia
Stability of mixtures   injection   Stability of mixtures : Nefopam     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,21 mg/ml
injection   Nefopam   
injection   Ketoprofene 0,93 mg/ml
20-24°C
24 Hour
Light 3075
Glass None 0,2 mg/ml
injection   Nefopam   
injection   Paracetamol 10 mg/ml
20-24°C
24 Hour
Light 3075
Glass None 0,20 mg/ml
injection   Nefopam   
injection   Paracetamol 9,86 mg/ml
injection   Ketoprofene 0,96 mg/ml
20-24°C
24 Hour
Light 3075
Polypropylen Syringe Sodium chloride 0,9% 2,5 mg/ml
injection   Nefopam   
injection   Droperidol 0,052 mg/ml
20-25°C
48 Hour
Light 4267
Level of evidence B+
Polyisoprene elastomer Sodium chloride 0,9% 0,8 mg/ml
injection   Nefopam   
injection   Fentanyl citrate 16 µg/ml
injection   Hydromorphone hydrochloride 0,08 mg/ml
injection   Ramosetron 12 µg/ml
24°C
4 Day
Protect from light 4666
Level of evidence D
Polyisoprene elastomer Sodium chloride 0,9% 0,8 mg/ml
injection   Nefopam   
injection   Fentanyl citrate 16 µg/ml
injection   Oxycodone hydrochloride 0,4 mg/ml
injection   Ondansetron hydrochloride 0,32 mg/ml
24°C
4 Day
Protect from light 4666
Level of evidence D
Polyisoprene elastomer Sodium chloride 0,9% 0,8 mg/ml
injection   Nefopam   
injection   Fentanyl citrate 16 µg/ml
injection   Oxycodone hydrochloride 0,4 mg/ml
injection   Ramosetron 12 µg/ml
24°C
4 Day
Protect from light 4666
Level of evidence D
Polyisoprene elastomer Sodium chloride 0,9% 0,8 mg/ml
injection   Nefopam   
injection   Fentanyl citrate 16 µg/ml
injection   Hydromorphone hydrochloride 0,08 mg/ml
injection   Ondansetron hydrochloride 0,32 mg/ml
24°C
4 Day
Protect from light 4666
Level of evidence D
  Mentions Légales