Last update :
19/11/2024
Anticoagulant   Argatroban  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Arganova France, Spain
Argatra Germany, Slovenia, Switzerland
Argatroban Canada, Germany, Great Britain, United States of America
Exembol Great Britain
Novastan Denmark, Finland, Japan, Norway, Sweden
Compatibility   injection   Compatibility : Argatroban              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Immediate precipitation Incompatible
injection Argatroban 1 mg/ml
injection Amiodarone hydrochloride 1.8 mg/ml
1963
Compatible
injection Argatroban 1 mg/ml
injection Atropine sulfate 0,4 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Diltiazem hydrochloride 1 mg/ml
Glucose 5% 3764
Compatible
injection Argatroban 1 mg/ml
injection Diphenhydramine hydrochloride 50 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Dobutamine hydrochloride 12,5 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Dopamine hydrochloride 80 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Eptifibatide 2 mg/ml
NaCl 0,9% or Glucose 5% 2004
Compatible
injection Argatroban 1 mg/ml
injection Esmolol hydrochloride 10 mg/ml
Glucose 5% 3764
Compatible
injection Argatroban 1 mg/ml
injection Fenoldopam mesylate 100 µg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Fentanyl citrate 500 µg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Furosemide 10 mg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Hydrocortisone sodium succinate 50 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Lidocaine hydrochloride 8 mg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Metoprolol tartrate 1 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Midazolam hydrochloride 2 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Milrinone lactate 0.4 mg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Morphine sulfate 10 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Nesiritide 0.006 mg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Nitroglycerin 0.2 mg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Nitroprusside sodium 0.2 mg/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Norepinephrine bitartrate 1 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Phenylephrine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Argatroban 1 mg/ml
injection Procainamide hydrochloride 4 mg/ml
Glucose 5% 3764
Compatible
injection Argatroban 1 mg/ml
injection Tirofiban 50 µg/ml
NaCl 0,9% or Glucose 5% 2004
Compatible
injection Argatroban 1 mg/ml
injection Vasopressin 0.4 UI/ml
Glucose 5% 1963
Compatible
injection Argatroban 1 mg/ml
injection Verapamil hydrochloride 2,5 mg/ml
Sodium chloride 0,9% 1964
Turbidity in 8 hours Incompatible
injection Argatroban 1 mg/ml
Parenteral nutrition (binary mixture) 1963

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