Last update :
19/11/2024
Beta-blocker   Propranolol hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Avlocardyl France, Morocco, Republic of South Africa, Tunisia
Dociton Germany
Inderal Ecuador, Great Britain, Greece, Ireland, Italy, Luxembourg, Portugal, Saudi Arabia, Sweden, Switzerland, United Arab Emirates
Mayestrotense Egypt
Oposim Argentina
Pranol Iran
Properol Malaysia
Propranolol Poland, United States of America
Propranolol clorhidrato Chile
Propranolol HCl United States of America
Propranolol hydrochloride Canada
Compatibility   injection   Compatibility : Propranolol hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Propranolol hydrochloride 0.5 mg/ml
injection Alteplase 0.5 mg/ml
Water for Injection 240
Immediate precipitation Incompatible
injection Propranolol hydrochloride 1 mg/ml
injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 1041
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Heparin sodium 1 UI/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Heparin sodium 1 UI/ml
Ringer’s lactate solution 1228
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Ringer’s lactate solution 1228
Immediate precipitation Incompatible
injection Propranolol hydrochloride 1 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Propranolol hydrochloride 0.3 & 0.5 mg/ml
injection Milrinone lactate 0.100 & 0.350 mg/ml
Glucose 5% 191
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 62
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Immediate precipitation Incompatible
injection Propranolol hydrochloride
injection Pantoprazole sodium
2090
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 62
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Instability of the emulsion after 6 hours Incompatible
injection Propranolol hydrochloride 1 mg/ml
injection Propofol
660
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Propofol 10 mg/ml
None 300
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
injection Propranolol hydrochloride
injection Tirofiban
1512
Compatible
injection Propranolol hydrochloride 1 mg/ml
injection Tirofiban 50 µg/ml
NaCl 0,9% or Glucose 5% 1603
Compatible
injection Propranolol hydrochloride 0.004 mg/ml
injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057

  Mentions Légales