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Anxiolytic   Midazolam hydrochloride  
Injection
Capsule Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Benzosed Ecuador, India, Venezuela
Buccolam Belgium, Germany
Crismidor Colombia
Dalam Argentina
Dormicum Argentina, Austria, Belgium, Colombia, Croatia, Denmark, Egypt, Finland, Germany, Greece, Hungary, Ireland, Mexico, Netherlands, Poland, Portugal, Republic of South Africa, Romania, Russian, Saudi Arabia, Slovenia, Spain, Sweden, Switzerland, Turkey, United Arab Emirates
Dormipron Colombia
Dormire Brazil, Chile
Dormomid Brazil, Chile
Gobbizolam Argentina
Hipnazolam Brazil
Hypnovel Australia, France, Great Britain, Morocco, New Zealand
Induson Brazil, Colombia
Lamcord Mexico
Midanium Poland
Midasedan Colombia
Midaselect Germany
Midozor Mexico
Relacum Brazil, Colombia, Ecuador, Mexico
Sedoz Colombia
Somnocal Mexico
Sopodorm Poland
Zolamid Portugal, Turkey
Zolmid Chile
Stability of mixtures   Injection   Stability of mixtures : Midazolam hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 2,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Morphine sulfate 2,5 & 5 mg/ml
20°C-25°C
14 Day
Protect from light 1492
Glass NaCl 0,9% or Glucose 5% 0,05 & 5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Tirofiban 50 µg/ml
20°C-25°C
4 Hour
Light 1603
Level of evidence A+
Glass Glucose 5% 1 mg/ml
Injection   Midazolam hydrochloride   
Injection   Palonosetron hydrochloride 25 µg/ml
20°C-25°C
4 Hour
Not specified 1975
Level of evidence A+
Glass Glucose 5% 0,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Milrinone lactate 0,2 mg/ml
22°C-23°C
4 Hour
Light 813
Level of evidence A
Glass Glucose 5% 0,1 & 0,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Fentanyl citrate 20 & 40 µg/ml
23°C-25°C
3 Hour
Light 225
Level of evidence C
Glass Glucose 5% 0,1 & 0,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Morphine sulfate 0,25 & 1 mg/ml
23°C-25°C
3 Hour
Light 86
Level of evidence C
Glass Glucose 5% 0,1 & 0,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Atracurium besylate 1 & 5 mg/ml
25°C
3 Hour
Light 865
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 0,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Morphine tartrate 1 mg/ml
22°C
28 Day
Protect from light 2083
Level of evidence B
Polypropylene NaCl 0,9% or Glucose 5% 4 mg/ml
Injection   Midazolam hydrochloride   
Injection   Methadone hydrochloride 0.2 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene Sodium chloride 0,9% 1,66 mg/ml
Injection   Midazolam hydrochloride   
Injection   Ondansetron hydrochloride 1,33 mg/ml
23°C
24 Hour
Light 815
Level of evidence C+
Polypropylene Sodium chloride 0,9% 3,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Clonidine hydrochloride 0,015 mg/ml
Injection   Sufentanil citrate 0,03 mg/ml
25°C
7 Day
Light 3705
Level of evidence D
Polypropylene Sodium chloride 0,9% 3,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Clonidine hydrochloride 0,015 mg/ml
25°C
7 Day
Light 3705
Level of evidence D
Polypropylene Sodium chloride 0,9% 3,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Ketamine hydrochloride 25 mg/ml
25°C
7 Day
Light 3705
Level of evidence D
Polypropylene Sodium chloride 0,9% 3,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Sufentanil citrate 0,03 mg/ml
25°C
7 Day
Light 3705
Level of evidence D
Polypropylene Sodium chloride 0,9% 3,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Clonidine hydrochloride 0,015 mg/ml
Injection   Piritramide 1 mg/ml
Injection   Ketamine hydrochloride 25 mg/ml
Injection   Lormetazepam 0,12 mg/ml
Injection   Sufentanil citrate 0,03 mg/ml
25°C
8 Hour
Light 3705
Level of evidence D
Polypropylene Sodium chloride 0,9% 1,2 mg/ml
Injection   Midazolam hydrochloride   
Injection   Propofol 6,7 mg/ml
Injection   Sufentanil citrate 0,0033 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 0,9 mg/ml
Injection   Midazolam hydrochloride   
Injection   Propofol 5 mg/ml
Injection   Sufentanil citrate 0,0075 mg/ml
Injection   Lormetazepam 0,03 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,2 mg/ml
Injection   Midazolam hydrochloride   
Injection   Remifentanil hydrochloride 1,7 µg/ml
Injection   Propofol 6,7 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,66 mg/ml
Injection   Midazolam hydrochloride   
Injection   Ondansetron hydrochloride 1,33 mg/ml
4°C
24 Hour
Protect from light 815
Level of evidence C+
Polypropylene Glucose 5% 4 mg/ml
Injection   Midazolam hydrochloride   
Injection   Dobutamine hydrochloride 8 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylen Syringe Water for Injection 0,66 & 5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Diamorphine hydrochloride 0,66 & 33 mg/ml
22°C
14 Day
Protect from light 1288
Level of evidence B
Polypropylen Syringe Water for Injection 0,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Fentanyl citrate 40 µg/ml
Injection   Scopolamine N-butyl bromide 0,85 mg/ml
32°C
10 Day
Protect from light 1405
Level of evidence B
Polypropylen Syringe Water for Injection 0,6 mg/ml
Injection   Midazolam hydrochloride   
Injection   Metoclopramide hydrochloride 0,7 mg/ml
Injection   Fentanyl citrate 40 µg/ml
32°C
10 Day
Protect from light 1405
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 0,66 & 0,9 mg/ml
Injection   Midazolam hydrochloride   
Injection   Fentanyl citrate 13 & 38 µg/ml
22°C
7 Day
Not specified 929
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml
Injection   Midazolam hydrochloride   
Injection   Famotidine 0,4 mg/ml
Injection   Hydromorphone hydrochloride 10 mg/ml
25°C
96 Hour
Not specified 2166
Polypropylen Syringe Sodium chloride 0,9% 0,66 & 0,9 mg/ml
Injection   Midazolam hydrochloride   
Injection   Fentanyl citrate 13 & 38 µg/ml
38°C
4 Day
Not specified 929
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml
Injection   Midazolam hydrochloride   
Injection   Famotidine 0,4 mg/ml
Injection   Hydromorphone hydrochloride 10 mg/ml
4°C
96 Hour
Not specified 2166
Polypropylen Syringe Sodium chloride 0,9% 0,66 & 0,9 mg/ml
Injection   Midazolam hydrochloride   
Injection   Fentanyl citrate 13 & 38 µg/ml
5°C
7 Day
Protect from light 929
Level of evidence B
Not specified NaCl 0,9% or Glucose 5% 0.1 & 0.5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Hydromorphone hydrochloride 2 & 20 mg/ml
23°C
23 Day
Protect from light 345
Level of evidence A
Not specified NaCl 0,9% or Glucose 5% 0.1 & 0.5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Hydromorphone hydrochloride 2 & 20 mg/ml
4°C
23 Day
Protect from light 345
Level of evidence A
Not specified Sodium chloride 0,9% 0,5 mg/ml
Injection   Midazolam hydrochloride   
Injection   Morphine tartrate 1 mg/ml
Injection   Bupivacaine hydrochloride 4 mg/ml
22°C
28 Day
Protect from light 2083
Level of evidence B
  Mentions Légales