Last update :
19/11/2024
Anticancer drug   Cladribine  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Biodribin Poland
Cladribine Canada, New Zealand, United States of America
Dricaleu Argentina
Intocel Argentina
Leustat Argentina, Great Britain
Leustatin Austria, Belgium, Brazil, Colombia, Denmark, Finland, Germany, Iran, Mexico, Norway, Portugal, Spain, Sweden, Switzerland, United States of America, Venezuela
Leustatine France
Litak Australia, Austria, Chile, Denmark, Finland, France, Germany, Great Britain, Switzerland
Ocladra Turkey
Compatibility   injection   Compatibility : Cladribine              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Cladribine 0.015 mg/ml
injection Aminophylline 2.5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Aminophylline 2.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Bumetanide 0.04 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Buprenorphine hydrochloride 0.04 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Butorphanol tartrate 0.04 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Calcium gluconate 40 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Carboplatin 5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Cimetidine hydrochloride 12 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Cisplatin 1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Cyclophosphamide 10 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Cytarabine 50 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Dexamethasone sodium phosphate 1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Diphenhydramine hydrochloride 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Dobutamine hydrochloride 4 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Doxorubicin hydrochloride 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Droperidol 0.4 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Enalaprilate 0.1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Etoposide 0.4 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Famotidine 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Folinate calcium 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Furosemide 3 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Gallium nitrate 0.4 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Haloperidol lactate 0.2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Heparin sodium 100 UI/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Hydroxyzine dihydrochloride 4 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Idarubicin hydrochloride 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Lorazepam 0.1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Mannitol 150 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Mesna 10 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Metoclopramide hydrochloride 5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Mitoxantrone dihydrochloride 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Morphine sulfate 1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Nalbuphine hydrochloride 10 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Paclitaxel 0.6 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Pethidine hydrochloride 4 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Potassium chloride 100 mEq/l
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Prochlorperazine edysilate 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Promethazine hydrochloride 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Ranitidine hydrochloride 2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Sodium bicarbonate 84 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Teniposide 0.1 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Vincristine sulfate 0.05 mg/ml
NaCl 0,9% + antibacterial 1496
Chemical instability Incompatible
injection Cladribine
Glucose 5% 3579
Compatible
injection Cladribine 0.015 mg/ml
injection Bumetanide 0.04 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Buprenorphine hydrochloride 0.04 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Butorphanol tartrate 0.04 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Calcium gluconate 40 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Carboplatin 5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Cimetidine hydrochloride 12 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Cisplatin 1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Cyclophosphamide 10 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Cytarabine 50 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Dexamethasone sodium phosphate 1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Diphenhydramine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Dobutamine hydrochloride 4 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Dopamine hydrochloride 3.2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.5 mg/ml
injection Dopamine hydrochloride 3.2 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Doxorubicin hydrochloride 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Droperidol 0.4 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Enalaprilate 0.1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Etoposide 0.4 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Famotidine 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Folinate calcium 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Furosemide 3 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Gallium nitrate 0.4 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Haloperidol lactate 0.2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Heparin sodium 100 UI/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Hydroxyzine dihydrochloride 4 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Idarubicin hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Lorazepam 0.1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Mannitol 150 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Mesna 10 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Metoclopramide hydrochloride 5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Mitoxantrone dihydrochloride 0.5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Morphine sulfate 1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Nalbuphine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Paclitaxel 0.6 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Pethidine hydrochloride 4 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Potassium chloride 100 mEq/l
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Prochlorperazine edysilate 0.5 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Promethazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Ranitidine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Sodium bicarbonate 84 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Teniposide 0.1 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Cladribine 0.015 mg/ml
injection Vincristine sulfate 0.05 mg/ml
Sodium chloride 0,9% 1496

  Mentions Légales