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Analgesic   Methadone hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Eptadone Italy
Ketalgin Switzerland
Mephenon Belgium
Metasedin Spain
Methadone
Physeptone Great Britain
Stability of mixtures   injection   Stability of mixtures : Methadone hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Polypropylene NaCl 0,9% or Glucose 5% 0.2 mg/ml
injection   Methadone hydrochloride   
injection   Dopamine hydrochloride 8 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene NaCl 0,9% or Glucose 5% 0.2 mg/ml
injection   Methadone hydrochloride   
injection   Dobutamine hydrochloride 8 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene NaCl 0,9% or Glucose 5% 0.2 mg/ml
injection   Methadone hydrochloride   
injection   Pantoprazole sodium 0.32 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene NaCl 0,9% or Glucose 5% 0.2 mg/ml
injection   Methadone hydrochloride   
injection   Midazolam hydrochloride 4 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
Polypropylene Sodium chloride 0,9% 0.2 mg/ml
injection   Methadone hydrochloride   
injection   Esomeprazole sodium 0.32 mg/ml
22-25°C
24 Hour
Protect from light 1506
Level of evidence B+
  Mentions Légales