Last update :
19/11/2024
Antimuscarinic   Scopolamine hydrobromide  
injection
nasal drops
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Dispamine Iran
Escopolamina Chile
Hyoscine Great Britain, Ireland, Malaysia
Lorcopan Iran
Scopolamine Belgium, France
Scopolamine hydrobromide United States of America
Compatibility   injection   Compatibility : Scopolamine hydrobromide              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Scopolamine hydrobromide 0,86 mg/ml
injection Cimetidine hydrochloride 150 mg/ml
1438
Compatible
injection Scopolamine hydrobromide 0.001 >> 0.003 mg/ml
injection Diamorphine hydrochloride 49.6 >> 372.5 mg/ml
None 1230
Compatible
injection Scopolamine hydrobromide 0.05 mg/ml
injection Fentanyl citrate 25 µg/ml
Glucose 5% 1974
Compatible
injection Scopolamine hydrobromide 0.86 mg/ml
injection Heparin sodium 1 UI/ml
Ringer’s lactate solution 1228
Compatible
injection Scopolamine hydrobromide 0.86 mg/ml
injection Heparin sodium 1 UI/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Scopolamine hydrobromide 0.86 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Ringer’s lactate solution 1228
Compatible
injection Scopolamine hydrobromide 0.86 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Scopolamine hydrobromide 0.05 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 1974
Compatible
injection Scopolamine hydrobromide 0.05 mg/ml
injection Methadone hydrochloride 1 mg/ml
Glucose 5% 1974
Compatible
injection Scopolamine hydrobromide 0.287 mg/ml
injection Midazolam hydrochloride 3.33 mg/ml
None 404
Compatible
injection Scopolamine hydrobromide 0.05 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Compatible
injection Scopolamine hydrobromide 0.05 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Compatible
injection Scopolamine hydrobromide 0,46 & 0,83 mg/ml
injection Nalbuphine hydrochloride 5 & 10 mg/ml
616
Compatible
injection Scopolamine hydrobromide 0.07 & 0.15 mg/ml
injection Oxycodone hydrochloride 14.7 & 38.5 mg/ml
Sodium chloride 0,9% 2900
Compatible
injection Scopolamine hydrobromide 0.03 & 0.09 mg/ml
injection Oxycodone hydrochloride 0.9 & 7.7 mg/ml
Water for Injection 2125
Compatible
injection Scopolamine hydrobromide 0.07 & 0.15 mg/ml
injection Oxycodone hydrochloride 14.7 & 38.5 mg/ml
Water for Injection 2900
Compatible
injection Scopolamine hydrobromide 0.03 & 0.09 mg/ml
injection Oxycodone hydrochloride 0.9 & 7.7 mg/ml
Sodium chloride 0,9% 2125
Compatible
injection Scopolamine hydrobromide 0.86 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Scopolamine hydrobromide 0.86 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Instability of the emulsion after 6 hours Incompatible
injection Scopolamine hydrobromide 0.4 mg/ml
injection Propofol
660
Compatible
injection Scopolamine hydrobromide 0.4 mg/ml
injection Propofol 10 mg/ml
None 300
Compatible
injection Scopolamine hydrobromide 0,4 mg/ml
injection Ranitidine hydrochloride 25 mg/ml
None 58

  Mentions Légales