Last update :
19/11/2024
Analgesic   Diamorphine hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Diamorphine hydrochloride for injection Great Britain
Diaphin Switzerland
Compatibility   injection   Compatibility : Diamorphine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Diamorphine hydrochloride 0,1 mg/ml
injection Bupivacaine hydrochloride 4 mg/ml
Glucose 8% 2308
Compatible
injection Diamorphine hydrochloride 0.02 mg/ml
injection Bupivacaine hydrochloride 1.5 mg/ml
Sodium chloride 0,9% 512
Compatible
injection Diamorphine hydrochloride 20 mg/ml
injection Cyclizine lactate 10 mg/ml
Water for Injection 1886
Compatible
injection Diamorphine hydrochloride 7.5 mg/ml
injection Cyclizine lactate 7.5 mg/ml
None 1230
Precipitation after 24 hours Incompatible
injection Diamorphine hydrochloride 25 >> 112.5 mg/ml
injection Cyclizine lactate 3.125 >> 25 mg/ml
None 1230
Incompatible
injection Diamorphine hydrochloride
Sodium chloride 0,9% 1385
Compatible
injection Diamorphine hydrochloride 20 >> 100 mg/ml
injection Cyclizine lactate 6.7 mg/ml
Water for Injection 1886
Immediate precipitation Incompatible
injection Diamorphine hydrochloride 10 mg/ml
injection Cyclizine lactate 25 mg/ml
788
Immediate precipitation Incompatible
injection Diamorphine hydrochloride > 25 mg/ml
injection Cyclizine lactate 10 mg/ml
Water for Injection 1886
Compatible
injection Diamorphine hydrochloride 0,5 mg/ml
injection Furosemide 1 mg/ml
Water for Injection 1232
Compatible
injection Diamorphine hydrochloride 6.25 & 12.5 mg/ml
injection Haloperidol lactate 0.31 mg/ml
None 779
Compatible
injection Diamorphine hydrochloride 18.18 mg/ml
injection Haloperidol lactate 0.18 mg/ml
None 1230
Immediate precipitation Incompatible
injection Diamorphine hydrochloride 45.45 >> 145.16 mg/ml
injection Haloperidol lactate 0.16 >> 0.45 mg/ml
None 1230
Compatible
injection Diamorphine hydrochloride 20 >> 100 mg/ml
injection Haloperidol lactate 0.75 mg/ml
Water for Injection 1886
Compatible
injection Diamorphine hydrochloride
injection Hyaluronidase
3184
Compatible
injection Diamorphine hydrochloride 45.45 >> 145.16 mg/ml
injection Metoclopramide hydrochloride 0.16 >> 0.45 mg/ml
None 1230
Compatible
injection Diamorphine hydrochloride 0,66 & 33 mg/ml
injection Midazolam hydrochloride 0,66 & 5 mg/ml
Water for Injection 1288
Compatible
injection Diamorphine hydrochloride 6,25 mg/ml
injection Octreotide acetate 0,075 mg/ml
Water for Injection 2404
Compatible
injection Diamorphine hydrochloride 6,25 mg/ml
injection Octreotide acetate 0,1125 mg/ml
Water for Injection 2404
Compatible
injection Diamorphine hydrochloride 6,25 mg/ml
injection Octreotide acetate 0,0375 mg/ml
Water for Injection 2404
Compatible
injection Diamorphine hydrochloride 12,5 mg/ml
injection Octreotide acetate 0,1125 mg/ml
Water for Injection 2404
Compatible
injection Diamorphine hydrochloride 25 mg/ml
injection Octreotide acetate 0,075 mg/ml
Water for Injection 2404
Compatible
injection Diamorphine hydrochloride 12,5 mg/ml
injection Octreotide acetate 0,0375 mg/ml
Water for Injection 2404
Compatible
injection Diamorphine hydrochloride 12,5 mg/ml
injection Octreotide acetate 0,075 mg/ml
Water for Injection 2404
Unspecified incompatibility Incompatible
injection Diamorphine hydrochloride
injection Parecoxib sodium
3504
Compatible
injection Diamorphine hydrochloride 49.6 >> 372.5 mg/ml
injection Scopolamine hydrobromide 0.001 >> 0.003 mg/ml
None 1230
Compatible
injection Diamorphine hydrochloride 41.67 >> 132.35 mg/ml
injection Scopolamine N-butyl bromide 2.35 >> 8 mg/ml
None 1230

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