Última actualización :
19/11/2024
Anestésico local   Bupivacaine hydrochloride  
Inyectables
Estabilidad en solucion Estabilidad en mezcla Factores que influyen sobre la estabilidad Compatibilidades método de inyección Bibliografía pdf
   Estructura química  

Nombre comercial   Nombre comercial     

Los nombres comerciales son orientativos y los excipientes de la formulación pueden ser distintos dependiendo del país y del laboratorio fabricante.

Bicain Finlandia
Bucain Alemania, Austria
Bucaine Arabia Saudita
Bupi Alleman Alemania
Bupinest Colombia, Ecuador
Bupirop Ecuador
Bupisen Italia
Bupivacain Alemania
Bupivacaina Chile, España
Bupivacaine Australia, Gran Bretaña, Irlanda, Marruecos, Túnez
Bupivan Alemania, Chile
Buvacaina México
Buvasin Turquía
Carbostesin Alemania, Austria
Dolanaest Alemania, Austria
Duracaine Argentina
Inibsacain España
Marcain Australia, Dinamarca, Egipto, Malasia, Nueva Zelanda
Marcaine Bélgica
Sensorcaine Canadá
Sinebupiv Ecuador
Bibliografía   Inyectables   Bibliografía : Bupivacaine hydrochloride  
Tipo Publicación
60 periódico Tu YH, Stiles ML, Allen LV Jr.
Stability of fentanyl citrate and bupivacaine hydrochloride in portable pump reservoirs.
Am J Hosp Pharm 1990 ; 47: 2037-2040.
217 periódico Allen LV, Stiles ML, Wang DP, Tu YH.
Stability of bupivacaine hydrochloride, epinephrine hydrochloride, and fentanyl citrate in portable infusion-pump reservoirs.
Am J Hosp Pharm 1993 ; 50: 714-715.
220 periódico Johnson CE, Christen C, Perez MM, Ma M.
Compatibility of bupivacaine hydrochloride and morphine sulfate.
Am J Health-Syst Pharm 1997 ; 54: 61-64.
221 periódico Neels JT.
Compatibility of bupivacaine hydrochloride with hydromorphone hydrochloride or morphine sulfate.
Am J Hosp Pharm 1992 ; 49: 2149.
293 periódico Jones JW, Davis AT.
Stability of bupivacaine hydrochloride in polypropylene syringes.
Am J Hosp Pharm 1993 ; 50: 2364-2365.
306 periódico Christen C, Johnson CE, Walters JR.
Stability of bupivacaine hydrochloride and hydromorphone hydrochloride during simulated epidural coadministration.
Am J Health-Syst Pharm 1996 ; 53: 170-173.
346 periódico Wulf H, Gleim M, Mignat C.
The stability of mixtures of morphine hydrochloride, bupivacaine hydrochloride, and clonidine hydrochloride in portable pump reservoirs for the management of chronic pain syndromes.
J Pain Symptom Manage 1994 ; 9: 308-311.
507 periódico Dawson PJ, Bjorksten AR, Duncan IP, Barnes RK, Beemer GH.
Stability of fentanyl, bupivacaine and adrenaline solutions for extradural infusion.
Br J Anaesth 1992 ; 68: 414-417.
510 periódico Roos PJ, Glerum JH, Schroeders MJH.
Effect of glucose 5% solution and bupivacaine hydrochloride on absorption of sufentanil citrate in a portable pump reservoir during storage and simulated infusion by an epidural catheter.
Pharm World Sci 1993 ; 15: 269-275.
512 periódico Barnes AR, Nash S.
Stability of bupivacaine hydrochloride with diamorphine hydrochloride in an epidural infusion.
Pharm World Sci 1995 ; 17: 87-92.
529 periódico Van Asten P, Glerum JH, Spaanderman ER, Van Niekerk J, Van Dijk A.
Compatibility of bupivacaine and iohexol in two mixtures for paediatric regional anaesthesia.
Pharm Weekbl [Sci] 1991 ; 13: 254-256.
1276 periódico Shiffman E, Walker SE, Yoon T, Yeung M.
Stability and compatibility of morphine with bupivacaine.
Can J Hosp Pharm 1998 ; 51: 110-116.
1292 periódico Grassby PF, Roberts DE.
Stability of epidural opiate solutions in 0.9 per cent sodium chloride infusion bags.
Int J Pharm Pract 1995 ; 3: 174-177.
1491 periódico Brouwers JRBJ, van Doorne H, Meevis RF, Boersma FP.
Stability of sufentanil citrate and sufentanil citrate/bupivacaine mixture in portable infusion pump reservoirs.
Eur Hosp Pharm 1995 ; 1: 12-14.
1707 periódico Trissel LA, Xu QA, Pham L.
Physical and chemical stability of low and high concentrations of morphine sulfate with bupivacaine hydrochloride packaged in plastic syringes.
Int J Pharm Compound 2002 ; 6: 70-73.
1723 periódico Sattler A, Jage J, Krämer I.
Physico-chemical stability of infusion solutions for epidural administration containing fentanyl and bupivacaine or lidocaine.
Pharmazie 1998 ; 53: 386-391.
1875 periódico Kjonniksen I, Brustugun J, Breivik H, Anderssen E, Klem W.
Stability of an epidural analgesic solution containing adrenaline, bupivacaine and fentanyl.
Acta Anaesthesiol Scand 2000 ; 44: 864-867.
1879 periódico Hildebrand KR, Elsberry DE, Deer TR.
Stability, compatibility, and safety of intrathecal bupivacaine administered via an implantable delivery system.
Clin J Pain 2001 : 17: 239-244.
1885 periódico Essink-Tjebbes CM, Burger DM, Beelen, Wuis EW, Heckster YA.
Long-term stability of morphine and bupivacaine mixture for spinal use.
Pharm World Sci 1999 ; 21: 144-146.
1909 periódico Farhang-Asnefi S, Barre J, Callaert S, Boutros A, Causse R, Thebault A.
Compatibilité et stabilité du mélange bupivacaïne-sufentanil en poche.
J Pharm Clin 2000 ; 19: 248-251.
1931 periódico Donnely RF.
Physical compatibility and chemical stability of bupivacaine and hydromorphone in polypropylene syringes.
Can J Hosp Pharm 2004 ; 4: 230-235.
1948 periódico Classen AM, Wimbish GH, Kupiec TC.
Stability of admixtures containing morphine sulfate, bupivacaine hydrochloride, and clonidine hydrochloride in an implantable infusion system.
J Pain Symptom Manage 2004 ; 28, 6: 603-611.
2083 periódico La Forgia SP, Sharley NA, Burgess NG, Doecke CJ.
Stability and compatibility of morphine, midazolam and bupivacaine combinaisons for iontravenous infusion.
J Pharm Pract and Res 2002 ; 32: 65-68.
2252 periódico Shields D, Montenegro R, Aclan J.
Chemical stability of admixture combining ziconotide and bupivacaine during simulated intrathecal administration.
Neuromodulation 2007 ; 10, 1: 1-5.
2305 periódico Bianchi F, Ginggen A, Tardy Y.
Stability and compatibility of drug mixtures in an implantable infusion system.
Anaesthesia 2008 63, 9: 972-978.
2306 periódico Priston M.J, Hughes J.M, Santillo M, Christie I.W.
Stability of an epidural analgesic admixture containing epinephrine, fentanyl and bupivacaine.
Anaesthesia 2004 ; 59, 10: 979-983.
2307 periódico Kreeger L, Cowin P, Noble-Gresty J, Naysmith A.
Epidural diamorphine and bupivacaine stability study.
Palliative Med 1995 ; 9, 4: 315-318.
2308 periódico Hudson S.J, Jones M.F, Nolan S, Ellis H, Duncombe R, Alexander-Williams J.M.
Stability of premixed syringes of diamorphine and hyperbaric bupivacaine.
Int J Obstet Anesth 2005 ; 14, 4: 284-287.
2319 periódico Janssen K, Wisselo R, Geerlings C, Schouten J.P.
Chemical stability of a solution of bupivacaine hydrochloride 0.125% and sufentanil citrate 0.5 µg/ml for filling syringes using a repeater pump.
EJHP Science 2009 ; 15, 1: 11-14.
3131 periódico Donnely RF, Wong K, Spencer J.
Physical compatibility of high-concentration bupivacaine with hydromorphone, morphine and fentanyl.
Can J Hosp Pharm 2010 ; 63, 2: 154-155.
3184 Laboratorio
Hyaluronidase (Hyalase®) - Summary of Product characteristics.
CP Pharmaceuticals 2005
3296 periódico Salmeron-Garcia A, Navas N, Martin A, Roman E, Cabeza J, Capitan-Vallvey L.F
Determination of Tramadol, Metamizole, Ropivacaine, and Bupivacaine in Analgesic Mixture Samples by HPLC with DAD Detection.
J Chromatographic Sci 2009 ; 47: 1-7.
3372 periódico Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S.
Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine.
Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3964 periódico Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G.
Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments.
Pharmactuel 2017 ; 50,1 : 27-33.
4200 periódico Macorigh C, Guibbert V, Casanova M, Haenni C.
Stability study of hydromorphone and bupivacaine mixture by HPLC-UV.
EJHP 2018
4319 periódico Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G.
Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs.
Hosp Pharm 2020 ; 55, 5: 332-337.
4603 periódico Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G.
Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration.
Hosp Pharm 2021 ; 56, 4: 228-234.
4746 póster Shead K, Derrick H, Lyons D, Law S, Ma N.H.
Stability and Compatibility of Bupivacaine and Hydromorphone in PVC and non-DEHP bags for 30 days at 4°C and 25°C.
2023

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