Monographie - Bupivacaine hydrochloride

Last update :
19/11/2024

Bupivacaine hydrochloride

Chemical structure

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Bicain	Finland
Bucain	Austria, Germany
Bucaine	Saudi Arabia
Bupi Alleman	Germany
Bupinest	Colombia, Ecuador
Bupirop	Ecuador
Bupisen	Italy
Bupivacain	Germany
Bupivacaina	Chile, Spain
Bupivacaine	Australia, Great Britain, Ireland, Morocco, Tunisia
Bupivan	Chile, Germany
Buvacaina	Mexico
Buvasin	Turkey
Carbostesin	Austria, Germany
Dolanaest	Austria, Germany
Duracaine	Argentina
Inibsacain	Spain
Marcain	Australia, Denmark, Egypt, Malaysia, New Zealand
Marcaine	Belgium
Sensorcaine	Canada
Sinebupiv	Ecuador

References : Bupivacaine hydrochloride

	Type	Publication
60	Journal	Tu YH, Stiles ML, Allen LV Jr. Stability of fentanyl citrate and bupivacaine hydrochloride in portable pump reservoirs. Am J Hosp Pharm 1990 ; 47: 2037-2040.
217	Journal	Allen LV, Stiles ML, Wang DP, Tu YH. Stability of bupivacaine hydrochloride, epinephrine hydrochloride, and fentanyl citrate in portable infusion-pump reservoirs. Am J Hosp Pharm 1993 ; 50: 714-715.
220	Journal	Johnson CE, Christen C, Perez MM, Ma M. Compatibility of bupivacaine hydrochloride and morphine sulfate. Am J Health-Syst Pharm 1997 ; 54: 61-64.
221	Journal	Neels JT. Compatibility of bupivacaine hydrochloride with hydromorphone hydrochloride or morphine sulfate. Am J Hosp Pharm 1992 ; 49: 2149.
293	Journal	Jones JW, Davis AT. Stability of bupivacaine hydrochloride in polypropylene syringes. Am J Hosp Pharm 1993 ; 50: 2364-2365.
306	Journal	Christen C, Johnson CE, Walters JR. Stability of bupivacaine hydrochloride and hydromorphone hydrochloride during simulated epidural coadministration. Am J Health-Syst Pharm 1996 ; 53: 170-173.
346	Journal	Wulf H, Gleim M, Mignat C. The stability of mixtures of morphine hydrochloride, bupivacaine hydrochloride, and clonidine hydrochloride in portable pump reservoirs for the management of chronic pain syndromes. J Pain Symptom Manage 1994 ; 9: 308-311.
507	Journal	Dawson PJ, Bjorksten AR, Duncan IP, Barnes RK, Beemer GH. Stability of fentanyl, bupivacaine and adrenaline solutions for extradural infusion. Br J Anaesth 1992 ; 68: 414-417.
510	Journal	Roos PJ, Glerum JH, Schroeders MJH. Effect of glucose 5% solution and bupivacaine hydrochloride on absorption of sufentanil citrate in a portable pump reservoir during storage and simulated infusion by an epidural catheter. Pharm World Sci 1993 ; 15: 269-275.
512	Journal	Barnes AR, Nash S. Stability of bupivacaine hydrochloride with diamorphine hydrochloride in an epidural infusion. Pharm World Sci 1995 ; 17: 87-92.
529	Journal	Van Asten P, Glerum JH, Spaanderman ER, Van Niekerk J, Van Dijk A. Compatibility of bupivacaine and iohexol in two mixtures for paediatric regional anaesthesia. Pharm Weekbl [Sci] 1991 ; 13: 254-256.
1276	Journal	Shiffman E, Walker SE, Yoon T, Yeung M. Stability and compatibility of morphine with bupivacaine. Can J Hosp Pharm 1998 ; 51: 110-116.
1292	Journal	Grassby PF, Roberts DE. Stability of epidural opiate solutions in 0.9 per cent sodium chloride infusion bags. Int J Pharm Pract 1995 ; 3: 174-177.
1491	Journal	Brouwers JRBJ, van Doorne H, Meevis RF, Boersma FP. Stability of sufentanil citrate and sufentanil citrate/bupivacaine mixture in portable infusion pump reservoirs. Eur Hosp Pharm 1995 ; 1: 12-14.
1707	Journal	Trissel LA, Xu QA, Pham L. Physical and chemical stability of low and high concentrations of morphine sulfate with bupivacaine hydrochloride packaged in plastic syringes. Int J Pharm Compound 2002 ; 6: 70-73.
1723	Journal	Sattler A, Jage J, Krämer I. Physico-chemical stability of infusion solutions for epidural administration containing fentanyl and bupivacaine or lidocaine. Pharmazie 1998 ; 53: 386-391.
1875	Journal	Kjonniksen I, Brustugun J, Breivik H, Anderssen E, Klem W. Stability of an epidural analgesic solution containing adrenaline, bupivacaine and fentanyl. Acta Anaesthesiol Scand 2000 ; 44: 864-867.
1879	Journal	Hildebrand KR, Elsberry DE, Deer TR. Stability, compatibility, and safety of intrathecal bupivacaine administered via an implantable delivery system. Clin J Pain 2001 : 17: 239-244.
1885	Journal	Essink-Tjebbes CM, Burger DM, Beelen, Wuis EW, Heckster YA. Long-term stability of morphine and bupivacaine mixture for spinal use. Pharm World Sci 1999 ; 21: 144-146.
1909	Journal	Farhang-Asnefi S, Barre J, Callaert S, Boutros A, Causse R, Thebault A. Compatibilité et stabilité du mélange bupivacaïne-sufentanil en poche. J Pharm Clin 2000 ; 19: 248-251.
1931	Journal	Donnely RF. Physical compatibility and chemical stability of bupivacaine and hydromorphone in polypropylene syringes. Can J Hosp Pharm 2004 ; 4: 230-235.
1948	Journal	Classen AM, Wimbish GH, Kupiec TC. Stability of admixtures containing morphine sulfate, bupivacaine hydrochloride, and clonidine hydrochloride in an implantable infusion system. J Pain Symptom Manage 2004 ; 28, 6: 603-611.
2083	Journal	La Forgia SP, Sharley NA, Burgess NG, Doecke CJ. Stability and compatibility of morphine, midazolam and bupivacaine combinaisons for iontravenous infusion. J Pharm Pract and Res 2002 ; 32: 65-68.
2252	Journal	Shields D, Montenegro R, Aclan J. Chemical stability of admixture combining ziconotide and bupivacaine during simulated intrathecal administration. Neuromodulation 2007 ; 10, 1: 1-5.
2305	Journal	Bianchi F, Ginggen A, Tardy Y. Stability and compatibility of drug mixtures in an implantable infusion system. Anaesthesia 2008 63, 9: 972-978.
2306	Journal	Priston M.J, Hughes J.M, Santillo M, Christie I.W. Stability of an epidural analgesic admixture containing epinephrine, fentanyl and bupivacaine. Anaesthesia 2004 ; 59, 10: 979-983.
2307	Journal	Kreeger L, Cowin P, Noble-Gresty J, Naysmith A. Epidural diamorphine and bupivacaine stability study. Palliative Med 1995 ; 9, 4: 315-318.
2308	Journal	Hudson S.J, Jones M.F, Nolan S, Ellis H, Duncombe R, Alexander-Williams J.M. Stability of premixed syringes of diamorphine and hyperbaric bupivacaine. Int J Obstet Anesth 2005 ; 14, 4: 284-287.
2319	Journal	Janssen K, Wisselo R, Geerlings C, Schouten J.P. Chemical stability of a solution of bupivacaine hydrochloride 0.125% and sufentanil citrate 0.5 µg/ml for filling syringes using a repeater pump. EJHP Science 2009 ; 15, 1: 11-14.
3131	Journal	Donnely RF, Wong K, Spencer J. Physical compatibility of high-concentration bupivacaine with hydromorphone, morphine and fentanyl. Can J Hosp Pharm 2010 ; 63, 2: 154-155.
3184	Manufacturer	Hyaluronidase (Hyalase®) - Summary of Product characteristics. CP Pharmaceuticals 2005
3296	Journal	Salmeron-Garcia A, Navas N, Martin A, Roman E, Cabeza J, Capitan-Vallvey L.F Determination of Tramadol, Metamizole, Ropivacaine, and Bupivacaine in Analgesic Mixture Samples by HPLC with DAD Detection. J Chromatographic Sci 2009 ; 47: 1-7.
3372	Journal	Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S. Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine. Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3964	Journal	Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G. Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments. Pharmactuel 2017 ; 50,1 : 27-33.
4200	Journal	Macorigh C, Guibbert V, Casanova M, Haenni C. Stability study of hydromorphone and bupivacaine mixture by HPLC-UV. EJHP 2018
4319	Journal	Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G. Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs. Hosp Pharm 2020 ; 55, 5: 332-337.
4603	Journal	Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G. Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration. Hosp Pharm 2021 ; 56, 4: 228-234.
4746	Poster	Shead K, Derrick H, Lyons D, Law S, Ma N.H. Stability and Compatibility of Bupivacaine and Hydromorphone in PVC and non-DEHP bags for 30 days at 4°C and 25°C. 2023

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