Last update :
14/12/2024
Antihypertensive   Hydralazine hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
Liposome   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Apresoline Canada
Hydralazine Great Britain, Spain, United States of America
Hydrapres Spain
Compatibility   injection   Compatibility : Hydralazine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Caffeine 10 mg/ml
None 3964
Chemical instability Incompatible
injection Hydralazine hydrochloride
Glucose 5% 2367
Compatible
injection Hydralazine hydrochloride 20 mg/ml
Ringer’s lactate solution 4603
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Caspofungin acetate 0.5 mg/ml
Sodium chloride 0,9% 2233
Color change after 4 hours Incompatible
injection Hydralazine hydrochloride 20 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Dexmedetomidine 100 µg/ml
4389
Compatible
injection Hydralazine hydrochloride 0,2 mg/ml
injection Dobutamine hydrochloride 0,2 mg/ml
Sodium chloride 0,9% 1221
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Heparin sodium 1 UI/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Heparin sodium 1 UI/ml
Ringer’s lactate solution 1228
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Ringer’s lactate solution 1228
Color change Incompatible
injection Hydralazine hydrochloride 20 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Hydralazine hydrochloride
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Hydralazine hydrochloride 1 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Color change Incompatible
injection Hydralazine hydrochloride 1 mg/ml
injection Nitroglycerin 0.4 mg/ml
NaCl 0,9% or Glucose 5% 1049
Precipitation after 4 hours Incompatible
injection Hydralazine hydrochloride
injection Pantoprazole sodium
2090
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Hydralazine hydrochloride 20 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Instability of the emulsion after 1 hour Incompatible
injection Hydralazine hydrochloride 20 mg/ml
injection Propofol
660
Color change Incompatible
injection Hydralazine hydrochloride 0.04 mg/ml
injection Verapamil hydrochloride 0.08 mg/ml
Glucose 5% 1057

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