Bibliographie - 5102 - Stabilis 4.0

Seneste opdatering :
03/03/2026

Bibliografi 5102

Type :

Journal

Internet-link :

https://pubmed.ncbi.nlm.nih.gov/38290833/

forskerhold :

Lille - Faculté des Sciences Pharmaceutiques et Biologiques

Forfattere :

Roche M, Rousseleau D, Danel C, Henry H, Lebuffe G, Odou P, Lannoy D, Simon N.

Titel :

Combination of a propofol emulsion with alpha-2 adrenergic receptor agonists used for multimodal analgesia or sedation in intensive care units: a physicochemical stability study

Nummer :

EJHP 2025;32:461–467. 2025

bevisniveau :

fysisk stabilitet :

kemisk stabilitet :

High Performance Liquid Chromatography - diodearraydetektor (HPLC-DAD)

Stabilitet defineres som 90% af den oprindelige koncentration

andre metoder :

Kommentarer :

Lister

Clonidine hydrochloride

Propofol

Dexmedetomidine

Propofol

		+ Clonidine hydrochloride		+
		+ Dexmedetomidine		+

25°C

Clonidine hydrochloride	0,010 mg/ml
Propofol	10,59 mg/ml

25°C

Propofol	16,36 mg/ml
Clonidine hydrochloride	0,004 mg/ml

25°C

Clonidine hydrochloride	0,016 mg/ml
Propofol	5,45 mg/ml

25°C

Clonidine hydrochloride	0,009 mg/ml
Propofol	12 mg/ml

25°C

Clonidine hydrochloride	0,015 mg/ml
Propofol	15,79 mg/ml

25°C

Propofol	18,75 mg/ml
Clonidine hydrochloride	0,004 mg/ml

25°C

Clonidine hydrochloride	0,033 mg/ml
Propofol	11,11 mg/ml

25°C

Clonidine hydrochloride	0,012 mg/ml
Propofol	16,67 mg/ml

25°C

Propofol	10,59 mg/ml
Dexmedetomidine	4,24 µg/ml

25°C

Propofol	16,36 mg/ml
Dexmedetomidine	1,64 µg/ml

25°C

Propofol	4,86 mg/ml
Dexmedetomidine	6,81 µg/ml

25°C

Propofol	11,25 mg/ml
Dexmedetomidine	3,94 µg/ml

25°C

Propofol	15,79 mg/ml
Dexmedetomidine	6,32 µg/ml

25°C

Propofol	18,75 mg/ml
Dexmedetomidine	1,88 µg/ml

25°C

Propofol	10,34 mg/ml
Dexmedetomidine	14,48 µg/ml

25°C

Propofol	16,22 mg/ml
Dexmedetomidine	5,68 µg/ml

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