Last update :
19/11/2024
References   References 5  
Type : Journal

Research teams : Oklahoma City - University of Oklahoma Health Sciences Center, College of Pharmacy
Authors : Stiles ML, Allen LV Jr, Prince SJ.
Title : Stability of deferoxamine mesylate, floxuridine, fluorouracil, hydromorphone hydrochloride, lorazepam, and midazolam hydrochloride in polypropylene infusion-pump syringes.
Reference : Am J Health-Syst Pharm ; 53: 1583-1588. 1996

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
No visual inspection

List of drugs
injectionDeferoxamine mesylate Chelator
Stability in solutions Polypropylen Syringe Water for Injection 250 mg/ml 30°C Not specified
14 Day
injectionFloxuridine Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 30°C Not specified
21 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 50 mg/ml 30°C Not specified
21 Day
injectionFluorouracil Anticancer drug
Stability in solutions Polypropylen Syringe None 50 mg/ml 30°C Not specified
21 Day
injectionHydromorphone hydrochloride Analgesic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 30°C Not specified
30 Day
Stability in solutions Polypropylen Syringe None 10 mg/ml 30°C Not specified
30 Day
injectionMidazolam hydrochloride Anxiolytic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 30°C Not specified
10 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 5°C Not specified
10 Day

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