Last update :
19/11/2024
References   References 2900  
Type : Journal
Web link : http://archive.eahp.eu/Media/Home-page/EJHP-BMJ/EJHP-Practice-archive/Issue-5-2009

Research teams :
Authors : Hines S, Pleasance S.
Title : Compatibility of an injectable high strength oxycodone formulation with typical diluents, syringes, tubings,infusion bags and drugs for potential co-administration.
Reference : EJHP ; 15, 5: 32-38. 2009

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionCyclizine lactate Antihistamine (H1)
Incompatible + injectionOxycodone hydrochloride + Sodium chloride 0,9%
Compatible 4.5 mg/ml + injectionOxycodone hydrochloride 45.5 mg/ml + Water for Injection
Incompatible 8.3 & 11.5 mg/ml + injectionOxycodone hydrochloride 38.5 & 41.7 mg/ml + Water for Injection
Compatible 4.4 & 8.8 mg/ml + injectionOxycodone hydrochloride 14.7 mg/ml + Water for Injection
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1.2 & 2 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 1.2 & 2 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
injectionGlycopyrronium bromide Antimuscarinic
Compatible 0.07 & 0.11 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 0.07 & 0.11 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
injectionHaloperidol lactate Neuroleptic
Compatible 0.4 & 1.2 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 0.4 & 1.2 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
injectionKetamine hydrochloride General anesthetic
Compatible 23.5 & 44.4 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 23.5 & 44.4 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
injectionLevomepromazine Neuroleptic
Compatible 5.9 & 11.11 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 5.9 & 11.11 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 2.9 & 3.3 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 2.9 & 3.3 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
injectionMidazolam hydrochloride Anxiolytic
Compatible 2.9 & 3.3 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 2.9 & 3.3 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
injectionOxycodone hydrochloride Analgesic
Incompatible + injectionCyclizine lactate + Sodium chloride 0,9%
Compatible 45.5 mg/ml + injectionCyclizine lactate 4.5 mg/ml + Water for Injection
Incompatible 38.5 & 41.7 mg/ml + injectionCyclizine lactate 8.3 & 11.5 mg/ml + Water for Injection
Compatible 14.7 mg/ml + injectionCyclizine lactate 4.4 & 8.8 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionDexamethasone sodium phosphate 1.2 & 2 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionDexamethasone sodium phosphate 1.2 & 2 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionGlycopyrronium bromide 0.07 & 0.11 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionGlycopyrronium bromide 0.07 & 0.11 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionHaloperidol lactate 0.4 & 1.2 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionHaloperidol lactate 0.4 & 1.2 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionKetamine hydrochloride 23.5 & 44.4 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionKetamine hydrochloride 23.5 & 44.4 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionLevomepromazine 5.9 & 11.11 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionLevomepromazine 5.9 & 11.11 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionMetoclopramide hydrochloride 2.9 & 3.3 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionMetoclopramide hydrochloride 2.9 & 3.3 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionMidazolam hydrochloride 2.9 & 3.3 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionMidazolam hydrochloride 2.9 & 3.3 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionScopolamine hydrobromide 0.07 & 0.15 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + injectionScopolamine hydrobromide 0.07 & 0.15 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionScopolamine N-butyl bromide 0.88 & 4.6 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + injectionScopolamine N-butyl bromide 0.88 & 4.6 mg/ml + Water for Injection
injectionScopolamine hydrobromide Antimuscarinic
Compatible 0.07 & 0.15 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 0.07 & 0.15 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
injectionScopolamine N-butyl bromide Antimuscarinic
Compatible 0.88 & 4.6 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 0.88 & 4.6 mg/ml + injectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection

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