Last update :
03/05/2024
References   References 2900  
Type : Journal
Web link : http://archive.eahp.eu/Media/Home-page/EJHP-BMJ/EJHP-Practice-archive/Issue-5-2009

Research teams :
Authors : Hines S, Pleasance S.
Title : Compatibility of an injectable high strength oxycodone formulation with typical diluents, syringes, tubings,infusion bags and drugs for potential co-administration.
Reference : EJHP ; 15, 5: 32-38. 2009

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionCyclizine lactate Antihistamine (H1)
Incompatible + InjectionOxycodone hydrochloride + Sodium chloride 0,9%
Compatible 4.5 mg/ml + InjectionOxycodone hydrochloride 45.5 mg/ml + Water for Injection
Incompatible 8.3 & 11.5 mg/ml + InjectionOxycodone hydrochloride 38.5 & 41.7 mg/ml + Water for Injection
Compatible 4.4 & 8.8 mg/ml + InjectionOxycodone hydrochloride 14.7 mg/ml + Water for Injection
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1.2 & 2 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 1.2 & 2 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
InjectionGlycopyrronium bromide Antimuscarinic
Compatible 0.07 & 0.11 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 0.07 & 0.11 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
InjectionHaloperidol lactate Neuroleptic
Compatible 0.4 & 1.2 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 0.4 & 1.2 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
InjectionKetamine hydrochloride General anesthetic
Compatible 23.5 & 44.4 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 23.5 & 44.4 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
InjectionLevomepromazine Neuroleptic
Compatible 5.9 & 11.11 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 5.9 & 11.11 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 2.9 & 3.3 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 2.9 & 3.3 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
InjectionMidazolam hydrochloride Anxiolytic
Compatible 2.9 & 3.3 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 2.9 & 3.3 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
InjectionOxycodone hydrochloride Analgesic
Incompatible + InjectionCyclizine lactate + Sodium chloride 0,9%
Compatible 45.5 mg/ml + InjectionCyclizine lactate 4.5 mg/ml + Water for Injection
Incompatible 38.5 & 41.7 mg/ml + InjectionCyclizine lactate 8.3 & 11.5 mg/ml + Water for Injection
Compatible 14.7 mg/ml + InjectionCyclizine lactate 4.4 & 8.8 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionDexamethasone sodium phosphate 1.2 & 2 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionDexamethasone sodium phosphate 1.2 & 2 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionGlycopyrronium bromide 0.07 & 0.11 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionGlycopyrronium bromide 0.07 & 0.11 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionHaloperidol lactate 0.4 & 1.2 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionHaloperidol lactate 0.4 & 1.2 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionKetamine hydrochloride 23.5 & 44.4 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionKetamine hydrochloride 23.5 & 44.4 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionLevomepromazine 5.9 & 11.11 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionLevomepromazine 5.9 & 11.11 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionMetoclopramide hydrochloride 2.9 & 3.3 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionMetoclopramide hydrochloride 2.9 & 3.3 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionMidazolam hydrochloride 2.9 & 3.3 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionMidazolam hydrochloride 2.9 & 3.3 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionScopolamine hydrobromide 0.07 & 0.15 mg/ml + Water for Injection
Compatible 14.7 & 38.5 mg/ml + InjectionScopolamine hydrobromide 0.07 & 0.15 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionScopolamine N-butyl bromide 0.88 & 4.6 mg/ml + Sodium chloride 0,9%
Compatible 14.7 & 38.5 mg/ml + InjectionScopolamine N-butyl bromide 0.88 & 4.6 mg/ml + Water for Injection
InjectionScopolamine hydrobromide Antimuscarinic
Compatible 0.07 & 0.15 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection
Compatible 0.07 & 0.15 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
InjectionScopolamine N-butyl bromide Antimuscarinic
Compatible 0.88 & 4.6 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Sodium chloride 0,9%
Compatible 0.88 & 4.6 mg/ml + InjectionOxycodone hydrochloride 14.7 & 38.5 mg/ml + Water for Injection

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