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References   References 288  
Type : Journal
Research teams : DallasDallas - Methodist Medical Center, Pharmacy Department
Authors : Cervenka P, Dejong DJ, Butler BL, Monzingo MD.
Title : Visual compatibility of injectable ciprofloxacin lactate with selected injectable drugs during simulated Y-site administration.
Reference : Hosp Pharm ; 27: 957-958,961-962. 1992
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
injectionAminophylline Various
Incompatible 2 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionCiprofloxacin lactate Antibiotic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 2 mg/ml + injectionAminophylline 2 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 mg/ml + injectionDexamethasone sodium phosphate 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionDigoxin 250 µg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionDiphenhydramine hydrochloride 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionDobutamine hydrochloride 0.25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionDopamine hydrochloride 1.6 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 mg/ml + injectionFurosemide 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionGentamicin sulfate 1.6 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 mg/ml + injectionHeparin sodium 100 UI/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 mg/ml + injectionHydrocortisone sodium succinate 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionHydroxyzine dihydrochloride 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionLidocaine hydrochloride 20 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionLidocaine hydrochloride 40 mg/ml + Glucose 5%
Incompatible 2 mg/ml + NaHCO3
Incompatible 2 mg/ml + injectionMagnesium sulfate 240 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionMagnesium sulfate 240 mg/ml + Glucose 5%
Incompatible 2 mg/ml + injectionMethylprednisolone sodium succinate 62.5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 mg/ml + injectionPhenytoin sodium 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionPotassium chloride 40 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionPromethazine hydrochloride 25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 mg/ml + injectionRanitidine hydrochloride 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 2 mg/ml + injectionVerapamil hydrochloride 2.5 mg/ml + NaCl 0,9% or Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 4 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 0.25 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 1.6 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 1.6 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 50 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionHydroxyzine dihydrochloride Anxiolytic
Compatible 50 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionLidocaine hydrochloride Local anesthetic
Compatible 20 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 40 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
injectionMagnesium sulfate Electrolyte
Incompatible 240 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Incompatible 240 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 62.5 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 40 mEq/l + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 25 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0.5 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
injectionVerapamil hydrochloride Anti-arrhythmic
Compatible 2.5 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + NaCl 0,9% or Glucose 5%
  Mentions Légales