Last update :
14/12/2024
References   References 213  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/47/7/1580

Research teams : Athens - University of Georgia, College of Pharmacy
Authors : Galante LJ, Stewart JT, Warren FW, Johnson SM, Duncan R.
Title : Stability of ranitidine hydrochloride at dilute concentration in intravenous infusion fluids at room temperature.
Reference : Am J Hosp Pharm ; 47: 1580-1584. 1990

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionRanitidine hydrochloride Antihistamine (H2)
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,05 mg/ml 20°C-25°C Light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 >> 2 mg/ml 20°C-25°C Light
28 Day
Stability in solutions Polyvinyl chloride Glucose 10% 0,05 mg/ml 20°C-25°C Light
2 Day

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